Thiophenes
Medchemexpress LLC Lesopitron dihydrochloride | 132449-89-9 | 98.0% | 393.74 g/mol | C15H23Cl3N6 | 5 MG
Lesopitron dihydrochloride is a selective, full agonist of the 5-HT1A receptor used in research to investigate serotonergic signaling and pharmacology. Supplier-reported data indicate activity in rodent tissues (IC50 ≈125 nM) and effects on adenylate cyclase activity and neuronal firing, supporting use in both in vitro and in vivo studies.
- Selective full 5-HT1A receptor agonist.
- Reported IC50 ≈125 nM in rat hippocampal membranes.
- Modulates forskolin-stimulated adenylate cyclase activity.
- Demonstrated activity in vitro and in vivo assays.
- Supplied in small, research-oriented pack sizes for pharmacology studies.
Medchemexpress LLC Way-100135 dihydrochloride | 149055-79-8 | 98.1% | 468.46 g/mol | C24H35Cl2N3O2 | 5 MG
WAY-100135 dihydrochloride is a research-grade small molecule used as a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. Supplied as the dihydrochloride salt with reported in vitro potency (IC50 ≈ 34 nM) and high purity, it is intended for pharmacology and neuroscience studies.
- Selective antagonist of 5-HT1A receptors.
- High purity suitable for analytical and preclinical research.
- Commonly used for receptor pharmacology and signaling studies.
- Available in small pack sizes for laboratory experiments.
- Molecular weight provided for dosing and calculation purposes.
Medchemexpress LLC Thiophene-2-amidoxim 500mg | 108443-93-2 | 142.18 g/mol | C5H6N2OS | 500 MG
Thiophene-2-amidoxime is a small-molecule synthetic intermediate used in pharmaceutical and medicinal chemistry as a precursor for constructing heterocyclic compounds and for method development in drug synthesis. It is supplied as a solid at research-grade purity for laboratory use.
- High purity suitable for research and synthesis applications.
- Solid form, easy to weigh and handle in standard laboratory procedures.
- Commonly used as a building block in heterocyclic and medicinal chemistry.
- Available in small lab-scale quantities for method development.
- Compatible with common organic solvents and standard synthetic reactions.
eMolecules 36052-27-4 | Methyl 3-aminopicolinate | ChemScene | MFCD08695602 | 152.153 | C7H8N2O2 | 97.000 | COC(=O)c1ncccc1N | 10g | 536904939
Methyl 3-aminopicolinate | ChemScene | 36052-27-4 | MFCD08695602 | 152.153 | C7H8N2O2 | 97.000 | COC(=O)c1ncccc1N | 10g | 536904939
eMolecules 6165-68-0 | Thiophene-2-boronic acid | Combi-Blocks | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 5g | 117520997
Thiophene-2-boronic acid | Combi-Blocks | 6165-68-0 | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 5g | 117520997
Medchemexpress LLC Lomerizine dihydrochloride | 101477-54-7 | 100.0% | 541.46 | C27H32Cl2F2N2O3 | 10 MG
Lomerizine dihydrochloride is a research chemical that acts as an antagonist of L-type and T-type voltage-gated calcium channels. It is used in preclinical and in vitro studies investigating calcium signaling, migraine mechanisms, and vascular effects.
- Antagonist of L- and T-type voltage-gated calcium channels.
- High reported purity (99.95%).
- Molecular weight 541.46 g/mol.
- CAS number 101477-54-7 for unambiguous identification.
- Supplied as a solid in 10 mg quantities for small-scale research use.
- Intended for research purposes; follow safety and handling guidance.
eMolecules 16694-17-0 | 4-Bromo-thiophene-3-carboxylic acid | J & W PharmLab LLC | MFCD01233020 | 207.040 | C5H3BrO2S | 96.000 | OC(=O)c1cscc1Br | 1g | 525338107
4-Bromo-thiophene-3-carboxylic acid | J & W PharmLab LLC | 16694-17-0 | MFCD01233020 | 207.040 | C5H3BrO2S | 96.000 | OC(=O)c1cscc1Br | 1g | 525338107
Apexbio Technology LLC Vatalanib (PTK787) 2HCl 212141-51-0 50mg
Vatalanib (PTK787) 2HCl (CAS 212141-51-0) is a small molecule inhibitor targeting vascular endothelial growth factor (VEGF) receptor tyrosine kinases including VEGFR/KDR (IC50 0 037 M) VEGFR/Flt-1 (IC50 0 077 M) and VEGFR/Flk (IC50 0 27 M) It also inhibits other receptor tyrosine kinases such as PDGFR- (IC50 0 58 M) c-Kit (IC50 0 73 M) and c-Fms (IC50 1 4 M) Through blockade of these pathways Vatalanib suppresses VEGF-mediated signaling and angiogenesis It is utilized in research investigating mechanisms of angiogenesis and has potential applications in studies of solid tumors and other angiogenesis-dependent diseases
Medchemexpress LLC Gyki 52466 dihydrochloride | 2319722-40-0 | MFCD00153803 | 99.8% | 366.24 g/mol | C17H17Cl2N3O2 | 10 MG
GYKI 52466 dihydrochloride is a selective, noncompetitive antagonist of AMPA and kainate ionotropic glutamate receptors used in pharmacological research into anticonvulsant effects, neuroprotection, and excitatory neurotransmission studies.
- Selective noncompetitive AMPA/kainate receptor antagonist.
- Orally active with documented anticonvulsant activity.
- High purity for research use (≈99.8%).
- Supplied in small-molecule research quantities (e.g., 10 MG).
- Molecular weight 366.24 g/mol; CAS 2319722-40-0.
- Store sealed, away from moisture and light; recommended storage at 4°C (in solvent: -80°C/-20°C for long-term/short-term).
Medchemexpress LLC RWJ-56110 (dihydrochloride) | 2387505-58-8 | 99.87% | 863.65 | 10 MG
RWJ-56110 (dihydrochloride) | 2387505-58-8 | 99.87% | 863.65 | 10 MG
Aobchem 1-(Dibenzo[b d]thiophen-2-yl)propan-1-one | 95% | CAS 147792-24-3 | C15H12OS | 250mg
1-(Dibenzo[b d]thiophen-2-yl)propan-1-one | 95% | CAS 147792-24-3 | C15H12OS | 250mg
Aobchem (5-Bromo-2-fluoro-3-(methylthio)phenyl)(cyclopropyl)methanone | 97% | C11H10BrFOS | 500mg
(5-Bromo-2-fluoro-3-(methylthio)phenyl)(cyclopropyl)methanone | 97% | C11H10BrFOS | 500mg
Aobchem 3-Chloro-4-fluoro-5-(methylthio)benzaldehyde | 97% | CAS 2755721-62-9 | C8H6ClFOS | 1g
3-Chloro-4-fluoro-5-(methylthio)benzaldehyde | 97% | CAS 2755721-62-9 | C8H6ClFOS | 1g
Aobchem 3-Bromo-5-(methylthio)thiophene-2-carboxylic acid | 95% | CAS 3002510-94-0 | C6H5BrO2S2 | 500mg
3-Bromo-5-(methylthio)thiophene-2-carboxylic acid | 95% | CAS 3002510-94-0 | C6H5BrO2S2 | 500mg