Thiophenes

Accela Chembio Inc 2-aminothiophene-3-carboxamide | 1g | 14080-51-4 | MFCD00706455 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4

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2-aminothiophene-3-carboxamide | 1g | 14080-51-4 | MFCD00706455 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4

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eMolecules​ METHYL 3-BROMOPROPIOLATE 10G

5000158734 METHYL 3-BROMOPROPIOLATE 10G

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Apexbio Technology LLC Quinacrine 2HCl 69-05-6 10mM (in 1mL H2O)

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Quinacrine 2HCl (69-05-6) is an orally active small-molecule inhibitor targeting the NF- B signaling pathway It is designed to inhibit the NF- B cascade thereby downregulating pro-survival gene expression and promoting apoptotic pathways in tumor cells Quinacrine 2HCl exerts its biological activity primarily through inhibition of NF- B and activation of the p53-dependent apoptotic pathway In in vitro studies Quinacrine 2HCl demonstrates growth inhibition of multiple cancer cell lines with reported IC50 values generally in the low micromolar range depending on the specific cell model and experimental context Based on these pharmacological properties Quinacrine 2HCl holds research potential in investigating apoptosis regulatory mechanisms NF- B pathway involvement in cancer biology and preclinical evaluation of potential anticancer therapies

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Apexbio Technology LLC 4-Methylhistamine dihydrochloride 36376-47-3 1mg

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4-Methylhistamine dihydrochloride (CAS 36376-47-3) is a selective agonist for the histamine H4 receptor (H4R) displaying a pEC50 of 7 4 0 1 at human H4R It exhibits over 100-fold selectivity for H4R relative to H3R and H2R and over 100 000-fold compared to H1R While affinity for human H4R is moderate it binds rat and mouse H4R with higher affinity (Ki values of 73 nM and 55 nM respectively) In in vivo models 4-Methylhistamine dihydrochloride modulates inflammatory signaling elevating TNF- and NF- B expression via JAK/STAT pathways in response to LPS-induced joint inflammation It serves as a valuable tool in studies of H4R-mediated immune regulation and inflammatory mechanisms

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eMolecules​ 4-BROMOTHIOPHENE-3-CARBOXYL 5G

5000164867 4-BROMOTHIOPHENE-3-CARBOXYL 5G

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Selleck Chemical LLC GSK-LSD1 2HCl

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GSK-LSD1 2HCl is an irreversible and selective LSD1 inhibitor with IC50 of 16 nM 1000 fold selective over other closely related FAD utilizing enzymes (i e LSD2 MAO-A MAO-B)

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eMolecules​ ChemScene / 2-Methoxyethane-1-sulfonyl fluoride / 25mg / 714145218 / CS-0253340 / 0.000 / 1087410-86-3 / MFCD18917239 / 142.140 / C3H7FO3S

ChemScene / 2-Methoxyethane-1-sulfonyl fluoride / 25mg / 714145218 / CS-0253340 / 0.000 / 1087410-86-3 / MFCD18917239 / 142.140 / C3H7FO3S

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Medchemexpress LLC PF-670462 dihydrochloride | 950912-80-8 | C19H22Cl2FN5 | 5 MG

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PF-670462 dihydrochloride is a potent and selective inhibitor of casein kinase (CK1ε and CK1δ) and a potent inhibitor of Wnt/β-catenin signaling. In vivo, it produces robust phase delays in circadian rhythms, affecting gene transcription in the liver, pancreas, and suprachiasmatic nucleus.

• Potent and selective inhibitor of CKIε and CKIδ
• Potent inhibitor of Wnt/β-catenin signaling
• Lower selectivity for EGFR and SAPK2A/p38
• Causes GFP signal redistribution to the cytoplasm
• Produces robust phase delays in circadian rhythms in rats
• Delays rhythmic transcription of Bmal1, Per1, Per2, and Nr1d1 in liver and pancreas
• Delays Nr1d1 and Dbp mRNA expression in the suprachiasmatic nucleus

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eMolecules​ 3-AMINO-PYRIDINE-2-CARBOXYL 5G

5000216305 3-AMINO-PYRIDINE-2-CARBOXYL 5G

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Medchemexpress LLC MEDCHEMEXPRESS LLC

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5000596905 CAD204520 DIHYDROCH 25MG

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eMolecules​ COPPERI THIOPHENE-2-CARB 25G

5000163222 COPPERI THIOPHENE-2-CARB 25G

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eMolecules​ 28748-67-6 | Methyl 2-Hydroxy-2-(Thiophen-2-Yl)-2-(Thiophen-3-Yl)Acetate | 250mg

Pharmablock | methyl 4-aminopyridine-2-carboxylate | 25mg | 586136647 | PB00482 | 71469-93-7 | MFCD00956000 | 152.153 | C7H8N2O2

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Medchemexpress LLC Ro 10-5824 dihydrochloride | 189744-94-3 | 99.9% | 353.29 | C17H22Cl2N4 | 1 ML

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Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist supplied for research use. It is offered as a ready-to-use 10 mM solution in DMSO (1 mL) or as a solid, and is characterized for potency, purity, and identity for receptor pharmacology and in vitro studies.

• Selective dopamine D4 receptor partial agonist with reported Ki = 5.2 nM.
• Provided as a 10 mM solution in DMSO (1 mL) or as solid quantities for custom dosing.
• High purity (reported 99.86%), suitable for analytical and biological assays.
• Molecular weight 353.29, chemical formula C17H22Cl2N4, CAS 189744-94-3.
• Characterized with supporting documentation including datasheet, COA, LCMS, and SDS.
• Intended for receptor pharmacology, signaling studies, and in vitro assay applications.

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Medchemexpress LLC Hoipin-1 | 99.6% | 304.28 | 100 MG

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Hoipin-1 | 99.6% | 304.28 | 100 MG

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eMolecules​ ETHYL 5-CHLORO-3-METHYLTHI 1G

5000164842 ETHYL 5-CHLORO-3-METHYLTHI 1G

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