Carboximidamides
Sigma Aldrich Fine Chemicals Biosciences Metformin Impurity A | 461-58-5 | MFCD00008066 | 25mg
Metformin Impurity A | Mol Wt: 84.08 | 461-58-5 | MFCD00008066 | 25mg
Medchemexpress LLC 6-methyl-2-((3-phenoxypropylamino)methyl)quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 | C20H22N2O2 | 50MG
UCSF924 is a potent and selective dopamine D4 receptor (DRD4) partial agonist used as a chemical probe in receptor pharmacology and neuropsychiatric research. It exhibits low-nanomolar activity (EC50 4.2 nM) and is supplied as a high-purity solid with recommended low-temperature storage for long-term stability.
- Potent DRD4 partial agonist (EC50 4.2 nM).
- High selectivity against other G protein-coupled receptors.
- Reported purity 99.53%.
- Molecular formula C20H22N2O2; molecular weight 322.40.
- Available in multiple pack sizes including 50 mg.
- Appearance: white to off-white solid; powder storage recommended at -20°C for long-term stability.
Medchemexpress LLC Guanidine hydrochloride | 50-01-1 | 98.0% | 100 G
Guanidine hydrochloride | 50-01-1 | 98.0% | 100 G
Medchemexpress LLC Guanidine hydrochloride | 50-01-1 | MFCD00013026 | 98.0% | 1 ML
Guanidine hydrochloride | 50-01-1 | MFCD00013026 | 98.0% | 1 ML
Medchemexpress LLC H3B-6545 | 2052130-80-8 | 99.4% | 567.58 | 10 MG
H3B-6545 is an oral, selective estrogen receptor covalent antagonist (SERCA) for the research of metastatic ER-positive, HER2-negative breast cancer. It is a first-in-class selective ER covalent antagonist (SERCA) that inactivates both wild-type and mutant ERα by targeting C530 and enforcing a unique antagonist conformation.
- Inactivates wild-type and mutant ERα by targeting C530.
- Enforces a unique antagonist conformation.
- Used for research of metastatic ER-positive, HER2-negative breast cancer.
- Shows potent activity in MCF-7 xenograft model.
- Well tolerated in rats and monkeys across a broad dose range.
TARGETMOL CHEMICALS INC CP 461 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CP 461 (UNII-68OJX9I7DT) a specific PDE2A inhibitor is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor cell lines in vitro and selectively induces apoptosis in cancer cell lines but not in normal cells. purity: 99%
Medchemexpress LLC RIPK3-IN-1 | 2361139-70-8 | 99.3% | 100 MG
RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. It inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 μM, respectively. It also acts as a c-Met kinase inhibitor with an IC50 of 1.1 μM. In vitro, RIPK3-IN-1 also inhibits ABL, BRAF/V599E, MAP4K3, and SRC with IC50s of 0.37, 0.15, 0.012, and 0.075 μM, respectively.
- Inhibits RIPK3 with high potency
- Targets RIPK1 and RIPK2
- Acts as a c-Met kinase inhibitor
- Exhibits additional inhibitory activity against ABL, BRAF/V599E, MAP4K3, and SRC
- Useful for studying necroptosis, a programmed form of cell death
- Relevant for research into various diseases including ischemia reperfusion injury, neurodegenerative disorders, pancreatic cancer, and autoimmune diseases like inflammatory bowel disease (IBD)
Medchemexpress LLC Creatine Kinase (CPK/CK), Bovine Heart (CK, CPK, Creatine Phosphokinase) | 9001-15-4 | 10 KU
Creatine Kinase (CPK/CK), Bovine Heart, also identified as CK, CPK, or Creatine Phosphokinase, is a biological material or organic compound specifically designed for life science research. This product is intended solely for research applications and is not available for patient use.
- Suitable for life science research applications.
- Provided as a biological material or organic compound.
Sigma Aldrich Fine Chemicals Biosciences Clonidine hydrochloride so1G
Clonidine hydrochloride has antihypertensive analgesic and antidiarrheal properties. It lowers short-circuit current blocks anion secretion improves mucosal absorption of fluids and electrolytes in vitro. Clonidine is used to treat attention deficit and hyperactivity disorders (ADHD) menopausal flushing drug withdrawal and Tourette syndrome.
Chem-Impex International, Inc. Chloro-dipyrrolidinocarbenium hexafluorophosphate | MFCD00191333 | 100G
Chloro-dipyrrolidinocarbenium hexafluorophosphate, MFCD00191333, 100G
eMolecules Medchem Express / AN0128 / 5mg / 705860157 / HY-10979 / / 872044-70-7 / MFCD18251581 / 400.060 / C20H16BCl2NO3
Medchem Express / AN0128 / 5mg / 705860157 / HY-10979 / / 872044-70-7 / MFCD18251581 / 400.060 / C20H16BCl2NO3
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 1 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 30 mL Glass (28-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 50.1 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
![eMolecules Ambeed / 55-(14-Phenylene)dipicolinaldehyde / 100mg / 603089926 / A1226399 / / 1399191-70-8 / [null] / 288.306 / C18H12N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502461975.JPG-250.jpg)
eMolecules Ambeed / 55-(14-Phenylene)dipicolinaldehyde / 100mg / 603089926 / A1226399 / / 1399191-70-8 / [null] / 288.306 / C18H12N2O2
Ambeed / 55-(14-Phenylene)dipicolinaldehyde / 100mg / 603089926 / A1226399 / / 1399191-70-8 / [null] / 288.306 / C18H12N2O2
Medchemexpress LLC 1-tert-butyl N-(5R)-substituted triazole-4-carboxamide (BIIB091) | 2247614-80-6 | 99.9% | 542.64 g/mol | C28H34N10O2 | 5 MG
BIIB091 is a potent, selective, orally active, reversible Bruton tyrosine kinase (BTK) inhibitor supplied for laboratory research. It shows sub-nanomolar enzymatic potency and is provided as solid material or as a DMSO solution for in vitro and preclinical studies; refer to the manufacturer datasheet for safety, handling, and the certificate of analysis.
- Sub-nanomolar BTK potency (IC50 <0.5 nM).
- Reversible and highly selective BTK inhibition.
- Chemical formula C28H34N10O2; molecular weight 542.64 g/mol.
- Available as solid quantities and as a 10 mM solution in DMSO.
- High purity (>99.8% by HPLC) suitable for research applications.