Enamines
![MEDCHEMEXPRESS LLC Benzamide, n-hydroxy-3-[1-[(phenylthio)methyl]-1h-1,2,3-triazol-4-yl]- | 1316652-41-1 | MFCD21363002 | 99.3% | 326.37 g/mol | C16H14N4O2S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000227030.png-250.jpg)
MEDCHEMEXPRESS LLC Benzamide, n-hydroxy-3-[1-[(phenylthio)methyl]-1h-1,2,3-triazol-4-yl]- | 1316652-41-1 | MFCD21363002 | 99.3% | 326.37 g/mol | C16H14N4O2S | 10 MG
NCC-149 is a selective histone deacetylase 8 (HDAC8) inhibitor used in neural differentiation research. It is a small-molecule benzamide derivative (C16H14N4O2S; MW 326.37 g/mol; CAS 1316652-41-1) supplied as a solid with documented purity and batch COA.
- Selective HDAC8 inhibitor useful for neural differentiation studies.
- Batch-specific purity reported at 99.3% (COA).
- Available as a small 10 MG solid suitable for research-scale experiments.
- Solid stable at -20°C for up to 3 years; solvent solutions require colder storage.
- Comes with COA, SDS, and product datasheet for quality and safety information.
MEDCHEMEXPRESS LLC CDK2-IN-4 | 1316652-41-1 | 99.3% | 326.37 g/mol | C16H14N4O2S | 5 MG
NCC-149 is a selective histone deacetylase 8 (HDAC8) inhibitor used in cell biology research, including studies of neural differentiation. The product is provided with supporting documentation for purity, handling, and storage, and is available both as a solid and as a DMSO solution.
- Selective HDAC8 inhibitor for neural differentiation studies.
- Documented purity approximately 99.3% based on certificate of analysis.
- Available as a solid and as a 10 mM solution in DMSO.
- Datasheet, certificate of analysis, and safety data sheet provided for quality and safety information.
- Storage recommendations included for powdered material and solutions.
MEDCHEMEXPRESS LLC PF-562271 besylate | 939791-38-5 | MFCD16038299 | 99.2% | 665.66 g·mol⁻¹ | C27H26F3N7O6S2 | 5 MG
PF-562271 besylate is a small-molecule, ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 used in research to study FAK pathway modulation. It is supplied as the besylate salt for laboratory use and has been evaluated in preclinical and clinical studies.
- Potent ATP-competitive inhibitor of FAK and Pyk2 (IC50 1.5 nM and 13 nM).
- Reversible mechanism suitable for biochemical and cellular assays.
- Supplied as besylate salt for improved stability and handling.
- High chemical purity (99.17%) for reproducible results.
- Molecular weight 665.66 g·mol⁻¹, molecular formula C27H26F3N7O6S2.
- Intended for research use only; not for human or veterinary use.
MEDCHEMEXPRESS LLC PF-562271 besylate | 939791-38-5 | MFCD14105612 | 99.2% | 665.66 | C27H26F3N7O6S2 | 10 MG
PF-562271 besylate is the besylate salt of PF-562271, a potent ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 used in cancer research to probe signaling pathways, tumor growth, and cell adhesion. The compound is supplied as a high-purity solid for in vitro and in vivo studies.
- Potent inhibition of FAK and Pyk2 (FAK IC50 ~1.5 nM; Pyk2 IC50 ~13 nM).
- High reported purity (99.17%).
- Provided as a solid, off-white to light-yellow material suitable for handling and formulation.
- Demonstrated antiproliferative activity in multiple human cell lines.
- Used for in vitro and in vivo studies of tumor growth, signaling, and angiogenesis.
- Available in a 10 mg package for research use.
MEDCHEMEXPRESS LLC (R)-Nimodipine | 77940-92-2 | 99.9% | 1 MG
(R)-Nimodipine | 77940-92-2 | 99.9% | 1 MG
MEDCHEMEXPRESS LLC (R)-Nimodipine | 77940-92-2 | 99.87% | 100 MG
(R)-Nimodipine is an orally active, blood-brain barrier-permeable L-type calcium channel blocker with an IC50 of 5 nM. It inhibits corticosterone release by blocking calcium channels on the hypothalamic-pituitary-adrenal axis, which can reverse immobilization stress-induced memory impairment and behavioral abnormalities. It is for research use only.
- Inhibits corticosterone release
- Reverses immobilization stress-induced memory impairment
- Used in studies related to aneurysmal subarachnoid hemorrhage
- Used in studies related to cerebral ischemia
- Used in studies related to epilepsy
- Used in studies related to age-related degenerative neurological diseases
- Used in studies related to alcohol intoxication
MEDCHEMEXPRESS LLC (R)-Nimodipine | 77940-92-2 | 99.9% | 50 MG
(R)-Nimodipine is an orally active, blood-brain barrier-permeable L-type calcium channel blocker with an IC50 of 5 nM. It inhibits corticosterone release by blocking calcium channels on the hypothalamic-pituitary-adrenal axis, which can reverse immobilization stress-induced memory impairment and behavioral abnormalities.
- Used in studies related to aneurysmal subarachnoid hemorrhage
- Used in studies related to cerebral ischemia
- Used in studies related to epilepsy
- Used in studies related to age-related degenerative neurological diseases
- Used in studies related to alcohol intoxication
MEDCHEMEXPRESS LLC Amlodipine maleate | 88150-47-4 | 99.9% | 5 G
Amlodipine maleate is a dihydropyridine calcium channel blocker that acts as an orally active antianginal agent. It blocks voltage-dependent L-type calcium channels, inhibiting the initial influx of calcium. This compound is used in research for high blood pressure and cancer studies.
- Blocks voltage-dependent L-type calcium channels
- Inhibits initial influx of calcium
- Attenuates uridine 5′-triphosphate (UTP)-induced increases of intracellular calcium
- Inhibits store-operated calcium influx
MEDCHEMEXPRESS LLC Amlodipine Besylate, USP | 111470-99-6 | MFCD00887594 | >=98% | 1 G
Amlodipine besylate is an antianginal agent and an orally active dihydropyridine calcium channel blocker. It functions by blocking voltage-dependent L-type calcium channels, which inhibits the initial influx of calcium. This compound is suitable for research related to high blood pressure and cancer.
- Antianginal agent: Used in research for angina.
- Orally active: Convenient for oral administration in research settings.
- Dihydropyridine calcium channel blocker: A specific type of calcium channel blocker with a well-defined mechanism of action.
- Mechanism of action: Blocks voltage-dependent L-type calcium channels, inhibiting calcium influx.
- Versatile research applications: Applicable for research concerning high blood pressure and cancer.
MEDCHEMEXPRESS LLC Amlodipine benzenesulfonate | 111470-99-6 | 99.7% | 500 MG
Amlodipine besylate (Amlodipine benzenesulfonate) is an orally active dihydropyridine calcium channel blocker and antianginal agent. It functions by blocking voltage-dependent L-type calcium channels, inhibiting initial calcium influx. This compound can be used for research into high blood pressure and cancer.
- Blocks voltage-dependent L-type calcium channels
- Inhibits initial influx of calcium
- Useful for high blood pressure research
- Useful for cancer research
MEDCHEMEXPRESS LLC Nimodipine | 66085-59-4 | 99.9% | 1 ML
Nimodipine is an orally active, well-tolerated, and light-sensitive dihydropyridine calcium antagonist. It is primarily used for the research of cerebrovascular disorders and is intended for research use only.
- Orally active and well-tolerated
- Light-sensitive dihydropyridine calcium antagonist
- Used in research for cerebrovascular disorders
- Available as a light yellow to yellow solid
- For research use only
MEDCHEMEXPRESS LLC Amlodipine besylate | 111470-99-6 | 99.7% | 1 ML
Amlodipine besylate is an antianginal agent and an orally active dihydropyridine calcium channel blocker. It functions by blocking voltage-dependent L-type calcium channels, which inhibits the initial influx of calcium. This product is for research use only and not sold to patients.
- Used for high blood pressure and cancer research
- Inhibits initial influx of calcium by blocking L-type channels
- Available as 10 mM in 1 mL solution in DMSO
MEDCHEMEXPRESS LLC Nimodipine (BAY-e 9736) | 66085-59-4 | 99.9% | 1 G
Nimodipine (BAY-e 9736) is an orally active, well-tolerated, and light-sensitive dihydropyridine calcium antagonist. It can be used for the research of cerebrovascular disorders.
- Orally active
- Well-tolerated
- Light-sensitive
- Dihydropyridine calcium antagonist
- Used for the research of cerebrovascular disorders
MEDCHEMEXPRESS LLC (R)-Nimodipine ((R)-BAY-e 9736) | 77940-92-2 | 99.9% | 5 MG
(R)-Nimodipine ((R)-BAY-e 9736) | 77940-92-2 | 99.9% | 5 MG