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Filtered Search Results
Medchemexpress LLC Imidapril (hydrochloride) | 89396-94-1 | MFCD00870777 | 99.9% | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Imidapril hydrochloride (TA-6366) is an orally active inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. It works by suppressing the conversion of angiotensin I to angiotensin II, which in turn reduces total peripheral resistance and systemic blood pressure. It is used in research for hypertension, type 1 diabetic nephropathy, and chronic heart failure.
- Orally active ACE and MMP-9 inhibitor
- Suppresses conversion of angiotensin I to angiotensin II
- Reduces total peripheral resistance and systemic blood pressure
- Used in research for hypertension
- Used in research for type 1 diabetic nephropathy
- Used in research for chronic heart failure
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Lecozotan hydrochloride | 433282-68-9 | 98.7% | 520.02 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Lecozotan hydrochloride (SRA-333) hydrochloride is an orally active and selective antagonist of 5-HT1A with a Ki of 4.5 nM for cloned human 5-HT1A receptor. It enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. This product has the potential for mild-to-moderate Alzheimer's disease (AD) research.
- Orally active and selective 5-HT1A antagonist.
- Enhances the release of glutamate and acetylcholine in the hippocampus.
- Possesses cognitive-enhancing properties.
- Potential for mild-to-moderate Alzheimer's disease research.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Elacridar hydrochloride | 143851-98-3 | 99.8% | C34H34ClN3O5 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Elacridar hydrochloride (GF120918A) is an orally active dual-inhibitor of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP). This compound is used for research to examine the influence of efflux transporters on agent distribution to the brain and for cancer research.
- Orally active P-glycoprotein (P-gp) inhibitor
- Orally active breast cancer resistance protein (BCRP) inhibitor
- Used to examine the influence of efflux transporters on agent distribution to the brain
- Applicable for cancer research
- Inhibits cell viability of 786-O cells in vitro
- Affects P-glycoprotein and ABCG2 protein expression levels in MCF-7 and 786-O cell lines
- Increases ⁹⁹mTc-MIBI intracellular accumulation in MCF-7 and 786-O cell lines
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Arg1-in-1 (hydrochloride) | 00-00-0 | 90.0% | 292.57 g·mol⁻1 | C11H22BClN2O4 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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ARG1-IN-1 hydrochloride is a small-molecule inhibitor of human arginase 1 with a reported IC50 of 29 nM. It is intended for research use in biochemical and cellular studies to probe arginase-related pathways. The hydrochloride form improves handling and aqueous compatibility for assay preparation.
- Potent arginase 1 inhibition (IC50 29 nM).
- Suitable for biochemical and cellular assays.
- Provided as a 5 mg quantity for small-scale research use.
- Molecular weight 292.57 g·mol⁻1; formula C11H22BClN2O4.
- Purity typically 90.0% as reported on the certificate of analysis.
- Store at -20°C under nitrogen and protect from moisture; in solvent store at -80°C for long-term.
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Medchemexpress LLC Pirlimycin hydrochloride | 78822-40-9 | MFCD27952783 | 99.1% | 447.42 g·mol⁻¹ | C17H32Cl2N2O5S | 1 MG
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Pirlimycin hydrochloride is a lincosamide-class antibiotic supplied as the hydrochloride salt for research use. It inhibits bacterial protein synthesis by binding the 50S ribosomal subunit and is primarily active against Gram-positive organisms. The material is provided as a solid at high purity for analytical and laboratory applications.
- Lincosamide antibiotic.
- Inhibits bacterial protein synthesis via 50S ribosomal binding.
- Primarily active against Gram-positive bacteria.
- High purity (99.1%).
- Supplied as a solid suitable for analytical use.
- Available in small-scale quantities for research.
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Medchemexpress LLC Pargyline hydrochloride | 306-07-0 | MFCD00012492 | 99.91% | C11H14ClN | 100 MG
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Pargyline hydrochloride is an irreversible monoamine oxidase (MAO) inhibitor with antihypertensive and anticancer activities. It functions as a click chemistry reagent, containing an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Irreversible monoamine oxidase (MAO) inhibitor
- Exhibits antihypertensive activities
- Demonstrates anticancer activities
- Functions as a click chemistry reagent
- Contains an alkyne group for CuAAc reactions
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Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 50 MG
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SB-408124 Hydrochloride is a selective non-peptide orexin receptor 1 (OX1) antagonist, which has demonstrated potent activity with Ki values of 57 nM and 27 nM in whole cell and membrane assays, respectively. It exhibits a high degree of specificity, showing 50-fold selectivity over the OX2 receptor. This compound is intended for research purposes only and is not sold to patients.
- Selective non-peptide orexin receptor 1 (OX1) antagonist.
- Ki values of 57 nM (whole cell) and 27 nM (membrane).
- Exhibits 50-fold selectivity over OX2 receptor.
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Medchemexpress LLC VTP-27999 (Hydrochloride) | 1264191-73-2 | 98.2% | C26H42Cl2N4O5 | 50 MG
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VTP-27999 Hydrochloride is an alkyl amine Renin inhibitor. It is useful for Hypertension and End-Organ Diseases. This product is for research use only and not sold to patients.
- Alkyl amine Renin inhibitor
- Useful for hypertension and end-organ diseases
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Tipiracil hydrochloride | 183204-72-0 | 99.9% | C9H12Cl2N4O2 | 100 MG
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Tipiracil hydrochloride is a thymidine phosphorylase inhibitor (TPI) used for cancer research. It exhibits antiangiogenic effects and inhibits the proliferation of endothelial cells. This compound is also a potent inhibitor of thymidine phosphorylase, an enzyme that degrades FTD. It is for research use only.
- Thymidine phosphorylase inhibitor (TPI)
- Exhibits antiangiogenic effects
- Inhibits the proliferation of endothelial cells
- Potent inhibitor of thymidine phosphorylase
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Medchemexpress LLC 1-Piperazinebutanol, α-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-, hydrochloride (1:1) | 105565-55-7 | 98.0% | 384.85 | 50 MG
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BMY-14802 hydrochloride is a potent agonist of 5-HT1A and adrenergic α1 receptors, known for its antipsychotic effects.
- Appearance: white to off-white solid.
- Storage: -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month.
- ¹H NMR spectrum consistent with structure.
- MS consistent with structure.
- Product tested and complies with given specifications.
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Medchemexpress LLC Caroverine hydrochloride | 55750-05-5 | 98.9% | 401.93 g/mol | C22H28ClN3O2 | 500 MG
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Caroverine hydrochloride is the hydrochloride salt of caroverine, a nonselective NMDA and AMPA glutamate receptor antagonist supplied for laboratory research use. It is provided as a dry powder for preparation of solution stocks and for in vitro or in vivo pharmacology studies.
- CAS number 55750-05-5.
- Molecular weight 401.93 g/mol.
- Chemical formula C22H28ClN3O2.
- Form white to off-white powder.
- Purity 98.9% (HPLC).
- Soluble in DMSO and water for stock preparation.
- Storage store sealed at 4°C, protect from moisture.
- Research use for NMDA/AMPA receptor pharmacology.
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Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | C22H31ClN2 | 50 MG
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Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. It primarily blocks sodium channels (INa) and significantly inhibits delayed potassium currents, helping to prolong the atrial effective refractory period (AERP) and prevent atrial fibrillation. It also regulates intracellular calcium ion concentration by inhibiting the Na+/Ca2+ exchange current (INCX), further stabilizing cardiac electrical activity. It is used in the study of atrial fibrillation (AF) and ventricular arrhythmias.
- Functions as an Ib-class anti-arrhythmic agent.
- Blocks sodium channels (INa) and inhibits delayed potassium currents.
- Regulates intracellular calcium ion concentration by inhibiting Na+/Ca2+ exchange current (INCX).
- Used for studying atrial fibrillation (AF) and ventricular arrhythmias.
- Inhibits proliferation of bone marrow cells and human lymphocytes.
- Demonstrates anti-arrhythmic effects in vivo.
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Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG
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Ansofaxine hydrochloride is a triple reuptake inhibitor designed to inhibit serotonin, dopamine, and norepinephrine reuptake. It demonstrates IC50 values of 723 nM, 491 nM, and 763 nM for these reuptake processes, respectively. This compound is intended for research use only.
- Triple reuptake inhibitor
- Inhibits serotonin, dopamine, and norepinephrine reuptake
- Intended for research use only
- Appears as a solid
- Color ranges from white to off-white
- Recommended storage for solid is 4°C, sealed and away from moisture
- For solutions, store at -80°C for up to 6 months, or -20°C for 1 month
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Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 5 MG
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Embramine hydrochloride is a monoethanolamine compound that functions as an antihistamine and anticholinergic. It is intended for research use only.
- Functions as an antihistamine
- Functions as an anticholinergic
- Monoethanolamine compound
- For research use only
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Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.9% | 338.85 | 10 MG
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AkaLumine hydrochloride is an analogue of D-luciferin that emits near-infrared (NIR) light (λmax=677 nm) when reacting with native firefly luciferase (Fluc) protein. It offers high tissue-penetration and increased detection sensitivity from deep-tissue targets.
- Near-infrared (NIR) emission allows for high tissue-penetration.
- Enhances detection sensitivity from deep-tissue targets.
- Functions similarly to D-luciferin with a specified Km for recombinant firefly luciferase.
- Can be used to detect Akaluc expression in vitro and for subcutaneous/orthotopic tumor mouse imaging in vivo.
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