Alcohols and polyols
- (1)
- (55)
- (354)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (31)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (400)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (14)
- (148)
- (116)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (1)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (13)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (4)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (2)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
- (1)
- (1)
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- (1)
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- (2)
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- (1)
- (1)
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- (1)
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- (9)
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- (1)
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- (2)
- (2)
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- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
- (2)
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- (3)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
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- (1)
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- (1)
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- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
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- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (82)
- (3)
- (379)
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- (40)
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- (1)
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- (1)
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- (16)
- (1)
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- (21)
- (2)
- (2)
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- (1)
- (67)
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- (2)
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- (4)
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- (1)
- (5)
- (72)
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- (2)
- (2)
- (21)
- (281)
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- (1)
- (6)
- (282)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (733)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
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- (1)
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- (2)
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- (1)
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- (1)
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- (2)
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- (2)
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- (3)
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- (2)
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- (2)
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- (2)
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- (3)
- (2)
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- (2)
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- (1)
- (7)
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- (2)
- (3)
- (2)
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- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
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- (6)
- (2)
- (1)
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- (3)
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- (1)
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- (2)
- (2)
- (2)
- (1)
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- (2)
- (3)
- (6)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (1)
- (12)
- (2)
- (10)
- (2)
- (1)
- (12)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
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- (1)
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Medchemexpress LLC Gyki 53655 Hydrochlo 10Mg | HY-103228-10MG
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Gyki 53655 Hydrochlo 10Mg
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Medchemexpress LLC Oxyfedrine hydrochloride | 16777-42-7 | MFCD01695148 | 99.9% | 349.85 g/mol | C19H24ClNO3 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Oxyfedrine hydrochloride is a β-adrenoreceptor agonist supplied as a ready-to-use 10 mM solution in DMSO (1 mL) for research applications. The accurately prepared solution simplifies assay setup and reduces measurement variability. Storage and handling recommendations are provided to maintain product stability.
- Prepared 10 mM solution in DMSO, 1 mL.
- High purity (99.9% by HPLC).
- Suitable for in vitro assays and compound screening.
- Includes storage and stability guidance for solvent and solid forms.
- Molecular formula C19H24ClNO3; molecular weight 349.85 g/mol.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Nordoxepin hydrochloride | 2887-91-4 | MFCD00135797 | 99.9% | 301.81 g·mol⁻¹ | C18H20ClNO | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Nordoxepin hydrochloride is the hydrochloride salt of nordoxepin (desmethyldoxepin), the primary metabolite of the tricyclic antidepressant doxepin. It is intended for research and analytical applications and is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and in multiple solid mass formats for analytical and synthetic workflows.
- High purity suitable for research applications (99.94%).
- Supplied as a ready-to-use 10 mM solution in DMSO for convenient dosing.
- Available in multiple solid mass sizes for synthetic and analytical work.
- Molecular weight 301.81 g·mol⁻¹ and formula C18H20ClNO for easy reference.
- Storage guidance: solid at 4°C; solution at -80°C (up to 6 months) or -20°C (up to 1 month).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Pargyline hydrochloride | 306-07-0 | 99.9% | C11H14ClN | 1 ML
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Pargyline hydrochloride is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM for MAO-A and 0.5 μM for MAO-B. It exhibits antihypertensive and anticancer activities. Pargyline (hydrochloride) is also a click chemistry reagent, containing an Alkyne group, which can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that have Azide groups.
- Irreversible monoamine oxidase (MAO) inhibitor
- Inhibits MAO-A with a Ki of 13 μM
- Inhibits MAO-B with a Ki of 0.5 μM
- Demonstrates antihypertensive activities
- Exhibits anticancer activities
- Functions as a click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
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Medchemexpress LLC Tipiracil hydrochloride | 183204-72-0 | 99.9% | C9H12Cl2N4O2 | 100 MG
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Tipiracil hydrochloride is a thymidine phosphorylase inhibitor (TPI) used for cancer research. It exhibits antiangiogenic effects and inhibits the proliferation of endothelial cells. This compound is also a potent inhibitor of thymidine phosphorylase, an enzyme that degrades FTD. It is for research use only.
- Thymidine phosphorylase inhibitor (TPI)
- Exhibits antiangiogenic effects
- Inhibits the proliferation of endothelial cells
- Potent inhibitor of thymidine phosphorylase
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Medchemexpress LLC Bleomycin (hydrochloride) | 67763-87-5 | 99.5% | 25 MG
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Bleomycin (hydrochloride) | 67763-87-5 | 99.5% | 25 MG
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Medchemexpress LLC CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 100 MG
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CP-640186 hydrochloride is an orally active and cell-permeable inhibitor of Acetyl-CoA carboxylase (ACC). It exhibits IC50 values of 53 nM for rat liver ACC1 and 61 nM for rat skeletal muscle ACC2. ACC is a crucial enzyme involved in fatty acid metabolism, responsible for synthesizing malonyl-CoA. This compound also promotes muscle fatty acid oxidation.
- Orally active and cell-permeable.
- Inhibits Acetyl-CoA carboxylase (ACC).
- IC50s: 53 nM for rat liver ACC1, 61 nM for rat skeletal muscle ACC2.
- Stimulates muscle fatty acid oxidation.
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![Medchemexpress LLC Benzoic acid, 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro [5.5]undec-9-yl]methyl]phenoxy]-, hydrochloride (1:1) | 461023-63-2 | 99.9% | 614.17 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386677-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzoic acid, 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro [5.5]undec-9-yl]methyl]phenoxy]-, hydrochloride (1:1) | 461023-63-2 | 99.9% | 614.17 | 1 ML
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Aplaviroc hydrochloride, an SDP derivative, is a potent CCR5 antagonist. It exhibits strong activity against various HIV-1 strains, including wild-type and multidrug-resistant variants, by binding to CCR5 with high affinity and inhibiting gp120/CD4 binding. This compound has been shown to suppress R5 HIV-1 viremia in in vivo models.
- Potent activity against three wild-type R5 HIV-1 strains (HIV-1Ba-L, HIV-1JRFL, and HIV-1MOKW).
- Substantially more potent than previously published CCR5 inhibitors.
- Suppresses infectivity and replication of two HIV-1MDR variants.
- Binds to CCR5 with high affinity.
- Potently blocks rgp120/sCD4 binding to CCR5.
- Exerts potent anti-R5 human immunodeficiency virus type 1 effects in a novel AIDS mouse model.
- Suppresses R5 HIV-1 viremia in hu-PBMC-NOG mice.
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Medchemexpress LLC Articaine (hydrochloride) | 23964-57-0 | 99.38% | 25 MG
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Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels (e.g., rNav1.4, hNav1.7, and rNav1.8). It exhibits local anesthetic activity by inhibiting Na+ influx to block nerve impulse conduction. Additionally, it can inhibit NF-κB activation and NLRP3 inflammasome pathways, demonstrating anti-inflammatory properties. This compound is suitable for studying dental local anesthesia and inflammatory-related diseases such as acute kidney injury.
- Selective inhibitor of voltage-gated sodium channels
- Exhibits local anesthetic activity by inhibiting Na+ influx
- Can inhibit NF-κB activation and NLRP3 inflammasome pathways
- Displays anti-inflammatory function
- Used in research for dental local anesthesia and inflammatory-related diseases
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Medchemexpress LLC Mefuparib hydrochloride | 1449746-00-2 | 98.6% | 334.77 | 5 MG
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Mefuparib hydrochloride is an orally active, substrate-competitive, and selective inhibitor of PARP1/2, with IC50 values of 3.2 nM and 1.9 nM respectively. It is known to induce apoptosis and exhibits significant anticancer activity both in vitro and in vivo.
- Orally active.
- Substrate-competitive and selective PARP1/2 inhibitor.
- Induces apoptosis.
- Possesses prominent anticancer activity in vitro and in vivo.
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Medchemexpress LLC PRT062607 Hydrochloride | 1370261-97-4 | 98.07% | 429.91 | 50 MG
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PRT062607 Hydrochloride is an orally available Syk inhibitor that effectively inhibits inflammation and induces apoptosis. It demonstrates potent antitumor activity in tumor xenograft mouse models. This compound inhibits phosphorylation of ERK, AKT, and SYK in Ramos cells, and BLNK Tyr84 phosphorylation in a concentration-dependent manner.
- Inhibits B cell antigen receptor-mediated B cell signaling and activation
- Inhibits Fc receptor 1-mediated induced basophil degranulation
- Produces dose-dependent anti-inflammatory activity in rodent models of rheumatoid arthritis
- Prevents BCR-induced splenomegaly in mice
- Prevents Ramos tumor formation in mouse xenograft models
- Significantly inhibits NHL tumor growth in xenograft models
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Medchemexpress LLC Asenapine hydrochloride (Org 5222 hydrochloride) | 1412458-61-7 | 99.95% | 322.23 | 50 MG
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Asenapine hydrochloride (Org 5222) is an atypical antipsychotic primarily investigated for its role in schizophrenia and bipolar disorder research. It acts as a potent antagonist across a diverse range of receptors, including serotonin, adrenoceptors, dopamine, and histamine.
- Exhibits higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B, and D3 receptors relative to its D2 receptor affinity.
- Potent antagonist (pKB) at 5-HT1A (7.4), 5-HT1B (8.1), 5-HT2A (9.0), 5-HT2B (9.3), 5-HT2C (9.0), 5-HT6 (8.0), 5-HT7 (8.5), D2 (9.1), D3 (9.1), α2A (7.3), α2B (8.3), α2C (6.8), and H1 (8.4) receptors.
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Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | MFCD00899568 | 99.5% | 458.08 g/mol | C27H40ClN3O | 1 ML
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Nevanimibe hydrochloride is the hydrochloride salt of nevanimibe, a selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor supplied as a 10 mM solution in DMSO (1 mL) for in vitro research use.
- Selective ACAT1 inhibitor with low-nanomolar activity
- Supplied as a ready-to-use 10 mM solution in DMSO
- High purity (~99.5%) suitable for biochemical and cell-based assays
- Molecular weight 458.08 g/mol aids solution preparation calculations
- Available in solid and solution formats for flexibility in workflows
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Medchemexpress LLC AMXI-5001 hydrochloride | 00-00-0 | 98.1% | C25H21ClFN5O3 | 10MG
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AMXI-5001 hydrochloride is a research-grade small molecule described as a dual inhibitor of PARP1/2 and microtubule polymerization. It shows potent cellular activity against PARP and tubulin targets, with reported favorable metabolic stability and oral bioavailability, and is intended for preclinical anticancer research.
- Dual mechanism: inhibits PARP1/2 and tubulin polymerization.
- Potent PARP inhibition with low nanomolar IC50s and tubulin inhibition in the micromolar range.
- Orally bioavailable with favorable pharmacokinetic properties.
- Suitable for in vitro and in vivo anticancer studies.
- High purity for research applications.
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Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 98.96% | C22H31ClN2 | 1 ML
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Aprindine hydrochloride | 33237-74-0 | 98.96% | C22H31ClN2 | 1 ML
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