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Filtered Search Results
Medchemexpress LLC SB-269970 hydrochloride | 261901-57-9 | C18H29ClN2O3S | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SB-269970 hydrochloride is a potent, selective, and brain-penetrant 5-HT7 receptor antagonist. It exhibits >50-fold selectivity against other 5-HT receptors, making it suitable for research into serotonin pathways and neurological conditions.
- Potent and selective 5-HT7 receptor antagonist
- Brain-penetrant
- High selectivity against other 5-HT receptors
- High purity
- White to off-white solid
- Molecular weight 388.95
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Golotimod (hydrochloride) | 1029401-59-9 | 99.79% | 369.80 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial activity. It significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. It also inhibits STAT3 signaling and modulates the duration and severity of oral mucositis, showing potential as a therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2).
- Immunomodulating peptide with antimicrobial activity
- Enhances antituberculosis therapy efficacy
- Stimulates thymic and splenic cell proliferation
- Improves macrophage function
- Inhibits STAT3 signaling
- Modulates duration and severity of oral mucositis
- Potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Epz020411 (hydrochloride) | 2070015-25-5 | 98.15% | 479.06 | 10 MG
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EPZ020411 hydrochloride is a selective inhibitor of PRMT6 with an IC50 of 10 nM. It demonstrates more than 10-fold selectivity for PRMT6 over PRMT1 and PRMT8. This compound can be utilized for cancer research.
- Selective inhibitor of PRMT6
- IC50 of 10 nM for PRMT6
- Exhibits greater than 10-fold selectivity for PRMT6 over PRMT1 and PRMT8
- Suitable for cancer research
- Off-white to light yellow solid appearance
- Soluble in DMSO, 0.1 M HCl, and water
- Stock solutions stable for 1 year at -80°C or 6 months at -20°C (under nitrogen)
- Shows synergistic anti-proliferative effects on HCT116 and SW620 cells
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SB-269970 hydrochloride | 261901-57-9 | MFCD03788020 | C18H29ClN2O3S | 10 MM * 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
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SB-269970 hydrochloride is a potent, selective, and brain-penetrant antagonist of the 5-HT7 receptor. It demonstrates over 50-fold selectivity against other 5-HT receptors with a pKi of 8.3.
- Potent and selective 5-HT7 receptor antagonist
- Brain-penetrant
- Exhibits over 50-fold selectivity against other 5-HT receptors
- Significantly blocks amphetamine and ketamine-induced hyperactivity in animal models
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Medchemexpress LLC Alpelisib hydrochloride | 1584128-91-5 | C19H23ClF3N5O2S | 500 MG
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Alpelisib hydrochloride (BYL-719) is a potent, selective, and orally active PI3Kα inhibitor with efficacy in targeting PIK3CA-mutated cancer. It exhibits antineoplastic activity.
- Potent, orally active, and selective PI3Kα inhibitor
- Inhibits PIK3CA somatic mutations (H1047R, E545K)
- Inhibits Akt phosphorylation in PI3Kα transformed cells
- Induces G0/G1 phase cell cycle arrest in osteosarcoma cell lines
- Significantly reduces tumor volumes in animal models
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Medchemexpress LLC W-7 (isomer hydrochloride) | 69762-85-2 | MFCD00151342 | 99.7% | 377.33 g/mol | C16H22Cl2N2O2S | 10 MG
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W-7 (isomer hydrochloride) is the hydrochloride salt of an isomer of W-7, a selective calmodulin antagonist used as a biochemical research reagent to study calmodulin-dependent signaling and related cellular processes. The compound has a molecular weight of 377.33 g/mol and a CAS number of 69762-85-2, and is supplied in high-purity form for laboratory applications.
- High purity (99.65%) suitable for research applications.
- Used as a calmodulin antagonist to probe calmodulin-dependent pathways.
- Available as solid and pre-formulated DMSO solutions for convenience.
- Supplied in small-scale quantities appropriate for research experiments.
- Comes with a safety data sheet and supporting documentation.
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Medchemexpress LLC Naluzotan hydrochlo | 5MG
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Naluzotan hydrochlo | 5MG
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Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | 259.73 | 10 MG
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Fadrozole hydrochloride | 102676-31-3 | 99.9% | 259.73 | 10 MG
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Medchemexpress LLC VU6036720 hydrochloride | 99.7% | 473.39 | 5 MG
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VU6036720 hydrochloride is a potent and specific in vitro inhibitor of Kir4.1/5.1. It can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM and can be used for the research of brain and kidney.
- Potent and specific in vitro inhibitor of Kir4.1/5.1.
- Inhibits Kir4.1/5.1 channels with an IC50 value of 0.24 μM.
- Useful for research pertaining to the brain.
- Useful for research pertaining to the kidney.
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Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 50 MG
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Embramine hydrochloride is a monoethanolamine used as an antihistamine and anticholinergic.
- Antihistamine
- Anticholinergic
- For research use only
- Related to Histamine receptor research
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Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 1 ML
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Defactinib hydrochloride is a small-molecule focal adhesion kinase (FAK) inhibitor that suppresses FAK Tyr397 phosphorylation in a time- and dose-dependent manner. It is supplied as the hydrochloride salt and is available as a 10 mM solution in DMSO (1 mL) or as solid samples for biochemical and cellular research.
- Inhibits FAK phosphorylation at Tyr397
- Supplied as hydrochloride salt for improved solubility
- Available as 10 mM solution in DMSO (1 mL) and as solid samples
- High purity suitable for research assays
- Useful for studies of cell migration, invasion, and signaling
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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 500 MG
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Trazodone hydrochloride is a triazolopyridine derivative classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity. The compound exerts antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.
- Serotonin receptor antagonist and reuptake inhibitor (SARI)
- Exhibits anti-depressant and anti-insomnious activities
- Antagonizes α1- and α2-adrenergic receptors and histamine H1 receptors
- Minimal anticholinergic effects
- Binds to 5-HT1A receptor
- Reduces expression of neuroinflammatory markers
- Increases mRNA expression of BDNF and CREB
- Demonstrates neuroprotective effects
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Medchemexpress LLC 4-thiazolecarboxamide, N-(2-aminoethyl)-5-(3-fluorophenyl)-, hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 | C12H13ClFN3OS | 10 MG
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Ro 41-1049 hydrochloride is the hydrochloride salt of a reversible, selective monoamine oxidase A (MAO-A) inhibitor supplied as a white to off-white solid for research use. The compound is intended for biochemical and pharmacological studies, including receptor binding and enzyme activity assays, and is provided with supporting analytical documentation.
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Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 100 MG
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Dopexamine hydrochloride is a β2 adrenergic receptor agonist, intended for research use only. This dopamine analogue exhibits agonist activity at β2 and dopaminergic receptors, making it suitable for studies on inflammatory response and organ protection.
- Attenuates systemic inflammatory response
- Reduces tissue leukocyte infiltration
- Protects against organ injury
- Reduces systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress
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Medchemexpress LLC Eglumegad hydrochloride | 176199-48-7 | 99.63% | 221.64 | 5 MG
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Eglumegad hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist. It protects neurons from NMDA toxicity and has anxiolytic- and antipsychotic-like effects.
- Highly potent and selective group II (mGlu2/3) receptor agonist.
- Protects neurons from NMDA toxicity.
- Has anxiolytic-like effects.
- Has antipsychotic-like effects.
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