Caspofungin diacetate, also known as MK-0991 diacetate or L-743872 diacetate, is a potent antifungal agent. Its mechanism of action involves inhibiting the synthesis of β-(l,3)-D-glucan, a crucial component of the fungal cell wall. This product is strictly for research use.
- Potent antifungal activity.
- Inhibits fungal cell wall synthesis by targeting β-(l,3)-D-glucan.
- Demonstrates central nervous system penetration in mice, leading to a reduction in Candida burden in the brain at dosages of 1-8 mg/kg (intraperitoneal, daily for 7 days).
- Exhibits a favorable safety profile at vitreal concentrations of 0.41 to 4.1 μM in mice, with nonsignificant alterations in ERG waveforms.
- Widely cited in numerous publications, affirming its utility in research applications.