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Isothiocyanates

Organosulfur compounds that contain a sulfur atom bonded to a carbon atom that is bonded to a nitrogen atom via two double bonds in the following structure: S=C=N.

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1

Medchemexpress LLC 1-Isothiocyanato-PEG4-alcohol | 1835759-69-7 | MFCD29052173 | C9H17NO4S | 50 MG
SDP

1-Isothiocyanato-PEG4-alcohol is a PEG-based PROTAC linker. It is intended for research use only, and not for sale to patients. PROTACs consist of two distinct ligands connected by a linker, where one ligand binds to an E3 ubiquitin ligase and the other to the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

  • PEG-based PROTAC linker
  • Utilized in the synthesis of PROTACs
  • Exploits the intracellular ubiquitin-proteasome system
  • Selectively degrades target proteins
  • For research use only

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2

TARGETMOL CHEMICALS INC OT-551 HCL 5MG
SDP

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. OT-551 HCl is an NF-(kappa)b inhibitor a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular degeneration and geographic atrophy (GA). purity: 99%

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3

TARGETMOL CHEMICALS INC MITO-TEMPO 25MG
SDP

Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties. purity: 98%

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4

Medchemexpress LLC 4-methoxyphenyl isothiocyanate | 2284-20-0 | MFCD00011676 | 165.21 g/mol | C8H7NOS | 1 G
SDP

4-Methoxyphenyl isothiocyanate is an organic isothiocyanate reagent used in biochemical research to evaluate antioxidant properties and cholinesterase interactions. It exhibits measurable radical-scavenging activity and partial inhibition of cholinesterase enzymes, and is supplied in small laboratory pack sizes for research applications.

  • CAS number 2284-20-0.
  • Molecular formula C8H7NOS; molecular weight 165.21 g/mol.
  • Reported antioxidant activity: DPPH IC50 = 1.25 mM; ORAC = 11.7 mM Trolox equivalents.
  • Partial cholinesterase inhibition: acetylcholinesterase ≈30.4%; butyrylcholinesterase ≈17.9%.
  • Available pack sizes: 1 g, 5 g, 10 g, 50 g.
  • Appearance: colorless to light yellow; solid-liquid mixture.

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