Organic disulfides
eMolecules Ambeed / N-Cyclohexyltaurine / 5g / 525245564 / A950389 / / 103-47-9 / MFCD00003835 / 207.290 / C8H17NO3S
Ambeed / N-Cyclohexyltaurine / 5g / 525245564 / A950389 / / 103-47-9 / MFCD00003835 / 207.290 / C8H17NO3S
Medchemexpress LLC 2,6-Dichlorodiphenylamine | 15307-93-4 | 99.78% | 238.11 | 100 MG
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and exhibits anti-Candida albicans activity. Diclofenac Sodium is described as a potent and nonselective anti-inflammatory agent that acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.
- Analogue of Diclofenac Sodium.
- Exhibits anti-Candida albicans activity.
- Potent and nonselective anti-inflammatory agent.
- Acts as a COX inhibitor.
Medchemexpress LLC (R)-Zelebrudomide | 3024312-52-2 | C39H45N9O5 | 100 MG
(R)-Zelebrudomide ((R)-NX-2127) is an isomer of the BTK PROTAC degrader Zelebrudomide. It is composed of a BTK ligand, (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline, and Thalidomide 5-fluoride. This product is intended for research use only.
- Isomer of the BTK PROTAC degrader Zelebrudomide
- Composed of a BTK ligand, (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline, and Thalidomide 5-fluoride
- For research use only
- High purity (98.93%)
Medchemexpress LLC (R)-Zelebrudomide | 3024312-52-2 | C39H45N9O5 | 25 MG
(R)-Zelebrudomide, also known as (R)-NX-2127, is an isomer of the BTK PROTAC degrader Zelebrudomide. It is used in cancer research and is supplied as a light yellow to yellow solid with a purity of 98.93%. This product is for research use only and has not been fully validated for medical applications.
- Isomer of BTK PROTAC degrader Zelebrudomide
- Used in cancer research
- Supplied as a light yellow to yellow solid
- Purity of 98.93%
Medchemexpress LLC NX-2127 | 2416131-46-7 | C39H45N9O5 | 500 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (Btk). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib. In vivo, it demonstrates potent degradation of BTK in cynomolgus monkeys and leads to superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice.
- Inhibits proliferation of BTKC481S mutant TMD8 cells
- Catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3)
- Stimulates T cell activation and increases IL-2 production
- Demonstrates potent degradation of BTK in cynomolgus monkeys
- Leads to superior tumor growth inhibition in xenograft models in mice
Medchemexpress LLC (R)-Zelebrudomide | 3024312-52-2 | C39H45N9O5 | 5 MG
(R)-Zelebrudomide is an isomer of the BTK PROTAC degrader Zelebrudomide. It is also known as (R)-NX-2127 and (R)-Compound 28. This compound includes a BTK ligand 10, (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline, and Thalidomide 5-fluoride.
- Purity: 98.93%
- Molecular weight: 719.83
- Appearance: Light yellow to yellow solid
- Storage: 4°C, protected from light; in solvent: -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC NX-2127 | 2416131-46-7 | C39H45N9O5 | 25 MG
NX-2127 is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (BTK). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib. NX-2127 catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) and stimulates T cell activation.
- Inhibits proliferation of BTK-C481S mutant TMD8 cells
- Catalyzes degradation of Ikaros (IKZF1) and Aiolos (IKZF3)
- Stimulates T cell activation and increases IL-2 production
- Potently degrades BTK in cynomolgus monkeys in vivo
- Leads to dose-proportional exposure in plasma
- Results in superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice
Medchemexpress LLC Dipropyl disulfide | 629-19-6 | MFCD00009378 | 99.3% | 150.31 g/mol | C6H14S2 | 1 ML
Dipropyl disulfide is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) for research applications. The compound has CAS number 629-19-6 and a reported purity of 99.3%. It is metabolized by flavin-containing monooxygenases and cytochrome P450 enzymes to produce metabolites such as propylglutathione sulfide conjugate and propylthiol. Intended for laboratory research use only.
- Ready-to-use 10 mM solution in DMSO.
- High reported purity (99.3%).
- Useful for metabolic and enzymatic studies.
- Includes CAS identifier for unambiguous identification.
- For research use only; not for clinical or human use.