Organic disulfides
![eMolecules 564483-18-7 | Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane | Combi-Blocks | MFCD04117682 | 476.729 | C33H49P | 97.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1ccccc1P(C1CCCCC1)C1CCCCC1 | 1g | 117541496](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000483106.jpg-250.jpg)
eMolecules 564483-18-7 | Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane | Combi-Blocks | MFCD04117682 | 476.729 | C33H49P | 97.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1ccccc1P(C1CCCCC1)C1CCCCC1 | 1g | 117541496
Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane | Combi-Blocks | 564483-18-7 | MFCD04117682 | 476.729 | C33H49P | 97.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1ccccc1P(C1CCCCC1)C1CCCCC1 | 1g | 117541496
![eMolecules 564483-18-7 | Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane | Combi-Blocks | MFCD04117682 | 476.729 | C33H49P | 97.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1ccccc1P(C1CCCCC1)C1CCCCC1 | 100g | 296391173](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000224565.jpg-250.jpg)
eMolecules 564483-18-7 | Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane | Combi-Blocks | MFCD04117682 | 476.729 | C33H49P | 97.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1ccccc1P(C1CCCCC1)C1CCCCC1 | 100g | 296391173
Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane | Combi-Blocks | 564483-18-7 | MFCD04117682 | 476.729 | C33H49P | 97.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1ccccc1P(C1CCCCC1)C1CCCCC1 | 100g | 296391173
Medchemexpress LLC Zelebrudomide (NX-2127) | 2416131-46-7 | C39H45N9O5 | 50 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (Btk). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib and appears as a light yellow to yellow solid. The compound has a molecular weight of 719.83.
- Targets Bruton's Tyrosine Kinase (Btk)
- Inhibits the proliferation of BTKC481S mutant TMD8 cells
- Catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3)
- Stimulates T cell activation
- Increases IL-2 production in primary human T cells
- Demonstrates potent degradation of BTK in cynomolgus monkeys in vivo
- Leads to superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice
Medchemexpress LLC (R)-Zelebrudomide | 3024312-52-2 | C39H45N9O5 | 100 MG
(R)-Zelebrudomide ((R)-NX-2127) is an isomer of the BTK PROTAC degrader Zelebrudomide. It is composed of a BTK ligand, (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline, and Thalidomide 5-fluoride. This product is intended for research use only.
- Isomer of the BTK PROTAC degrader Zelebrudomide
- Composed of a BTK ligand, (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline, and Thalidomide 5-fluoride
- For research use only
- High purity (98.93%)
Medchemexpress LLC Dipropyl disulfide | 629-19-6 | MFCD00009378 | 99.3% | 150.31 g/mol | C6H14S2 | 1 ML
Dipropyl disulfide is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) for research applications. The compound has CAS number 629-19-6 and a reported purity of 99.3%. It is metabolized by flavin-containing monooxygenases and cytochrome P450 enzymes to produce metabolites such as propylglutathione sulfide conjugate and propylthiol. Intended for laboratory research use only.
- Ready-to-use 10 mM solution in DMSO.
- High reported purity (99.3%).
- Useful for metabolic and enzymatic studies.
- Includes CAS identifier for unambiguous identification.
- For research use only; not for clinical or human use.
Medchemexpress LLC (R)-NX-2127 | 3024312-52-2 | 98.9% | 719.83 | C39H45N9O5 | 10 MG
(R)-NX-2127 is the R-isomer of a Bruton's tyrosine kinase (BTK) PROTAC degrader supplied as a high-purity solid for preclinical research. The compound is intended for use in studies of BTK degradation and related cellular pharmacology; consult the supplier product page and SDS for handling and storage details.
- R-isomer of a BTK PROTAC degrader
- High reported purity (98.93%)
- Molecular weight 719.83
- Chemical formula C39H45N9O5
- Solid, light yellow to yellow appearance
- Recommended storage: 4°C protected from light; in solvent -80°C (6 months) or -20°C (1 month)
- Intended for preclinical BTK degradation and cellular assays
Medchemexpress LLC Dibenzyl disulfide | 150-60-7 | 99.9% | 246.39 | 1 ML
Dibenzyl disulfide is an endogenous metabolite for research use.
- Purity of 99.94%
- Molecular weight of 246.39
- Chemical formula C14H14S2
- CAS number 150-60-7
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL
- Recommended storage for powder at -20°C for 3 years or 4°C for 2 years
- Recommended storage for solutions at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Hydroxyethyl disulfide | 1892-29-1 | MFCD00002906 | 98.8% | 154.25 g/mol | C4H10O2S2 | 10 G
Hydroxyethyl disulfide is a small-molecule laboratory reagent used in biochemical research. It is reported to interact with thymidylate synthase pathways and is provided with supporting documentation such as a certificate of analysis and safety data sheet. The compound is commonly used as a reagent or intermediate in chemical and biochemical studies.
- Purity 98.8% (reported)
- Cas number 1892-29-1
- Molecular formula C4H10O2S2
- Molecular weight 154.25 g/mol
- Available as a 10 G package
Medchemexpress LLC Captopril disulfide | 64806-05-9 | MFCD08063643 | 99.3% | 432.55 g/mol | C18H28N2O6S2 | 50MG
Captopril disulfide is the symmetrical disulfide metabolite of captopril provided as a research/analytical standard with reported antihypertensive activity via angiotensin-converting enzyme inhibition. The compound is supplied in multiple small pack sizes for laboratory use.
Selleck Chemical LLC NX-2127-E1381-25MG
NX-2127 is a unique potent inhibitor of BTK that prevents its functions by catalyzing the ubiquitylation and proteasomal degradation of BTK rather than via direct binding NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells
Apexbio Technology LLC DIPHENYL-DISULFIDE-1G
Diphenyl disulfide (CAS No 882-33-7) is widely utilized in biomedical research particularly in the study of oxidative stress and sulfur-containing compound mechanisms Originating as an organosulfur compound it functions by modulating redox signaling pathways and altering thiol-disulfide exchange reactions In vitro its activity is observed in nanomolar to low micromolar ranges making it effective in various biochemical assays Commonly it is used in cellular models to investigate oxidative damage responses and in animal studies to evaluate potential therapeutic effects against oxidative stress-related conditions It also serves as a tool in drug screening processes to identify agents affecting disulfide bond dynamics Experimental concentrations typically depend on the specific research design ensuring adaptability across different experimental setups
Apexbio Technology LLC DIBENZYL-DISULFIDE-500MG
Dibenzyl disulfide (CAS No 150-60-7) is a significant compound in biomedical research particularly in the study of oxidative stress and cell signaling pathways Originating from natural sources like Allium vegetables it is known for its potential to modulate biochemical pathways related to enzymatic antioxidant activities Research indicates its influence on the reduction of oxidative stress via the regulation of reactive oxygen species Dibenzyl disulfide exhibits common in vitro activity in the nanomolar to low micromolar range It is utilized in various applications including cell models examining cancer cell lines and animal studies exploring its pharmacological effects Additionally its role in drug screening highlights its potential as an adjunct or alternative therapeutic agent Experimental concentrations typically depend on the specific research design ensuring adaptability across different study frameworks and objectives