Sulfonyls
Apexbio Technology LLC Sulfanilamide 63-74-1 10mM (in 1mL DMSO)
Sulfanilamide is a competitive inhibitor targeting bacterial dihydropteroate synthetase (DHPS) an enzyme essential in microbial folate biosynthesis pathway By inhibiting DHPS the compound limits synthesis of dihydrofolate a precursor crucial for bacterial DNA replication and proliferation In enzymatic assays evaluating inhibition potency Sulfanilamide demonstrates an IC50 value of approximately 320 M Due to its defined mode of action Sulfanilamide is extensively utilized in microbiology and pharmacology research particularly for investigating bacterial metabolic pathways resistance mechanisms and screening potential antibacterial agents
Medchemexpress LLC Sulfathiazole (sodium) | 144-74-1 | 99.9% | 1 ML
Sulfathiazole sodium is an analytical standard suitable for research and analytical applications such as HPLC, GC, and MS. It acts as an orally active endocrine disruptor, notably enhancing CYP19 activity in human adrenal cancer cells (H295R) and upregulating the mRNA expression of CYP17, CYP19, and 3β-HSD. The compound also increases 17-estradiol (E2) production and exhibits endocrine disrupting effects on aquatic organisms. Furthermore, it functions as a cathodic corrosion inhibitor by reducing corrosion current density and shifting corrosion potential negatively.
- Enhances CYP19 activity in human adrenal cancer cells
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases 17-estradiol (E2) production
- Exhibits endocrine disrupting effects on aquatic organisms
- Inhibits copper corrosion by chloride ions
eMolecules 5934-14-5 | 4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid | MFCD00864826 | 1g
Ambeed | 4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid | 1g | 503282134 | A244444 | 5934-14-5 | MFCD00864826 | 348.370 | C16H16N2O5S
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Medchemexpress LLC Sulfapyridine | 144-83-2 | 99.9% | 1 ML
Sulfapyridine is a sulfonamide antibiotic agent and a major metabolite of Sulfasalazine. It inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. It exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities.
- Inhibits recombinant P. carinii dihydropteroate synthetase (DHPS)
- Exhibits antibacterial properties
- Possesses anti-inflammatory activity
- Shows anti-rheumatic activity
- Inhibits production of IL-8, CXCL1, and MCP-1 in synovial cells of rheumatoid arthritis (RA)
- Significantly inhibits systemic allergic reactions induced by compound 48/80 in rats
Medchemexpress LLC Sulfanilamide | 63-74-1 | 99.3% | 1 G
Sulfanilamide is a potent and orally active sulfonamide antibiotic, also serving as a major intermediate in sulfamethoxazole biodegradation. This compound acts as a carbonic anhydrase inhibitor and has demonstrated inhibition against the virus of lymphogranuloma venereum. It presents as a white to off-white solid and is intended solely for research and analytical applications.
- Potent and orally active sulfonamide antibiotic properties
- Functions as a carbonic anhydrase inhibitor
- Exhibits inhibition against the virus of lymphogranuloma venereum
- Store powder at -20°C for up to 3 years, or 4°C for up to 2 years
- Store in solvent at -80°C for up to 2 years, or -20°C for up to 1 year
Medchemexpress LLC Sulfanilamide | 63-74-1 | 99.93% | 5 G
Sulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. It is also a carbonic anhydrase inhibitor and shows inhibition on the virus of lymphogranuloma venereum.
- Potent and orally active sulfonamide antibiotic
- Major intermediate of sulfamethoxazole biodegradation
- Carbonic anhydrase inhibitor
- Shows inhibition on the virus of lymphogranuloma venereum
Sigma Aldrich Fine Chemicals Biosciences Sulfanilamide European Pharmacopoeia (EP) Reference Standard | 63-74-1 | MFCD00007939 |
Sulfanilamide European Pharmacopoeia (EP) Reference Standard | Mol Wt: 172.2 | 63-74-1 | MFCD00007939 |
Medchemexpress LLC Sulfadiazine (standard) | 68-35-9 | 99.8% | 50 MG
Sulfadiazine (Standard) is the analytical standard of Sulfadiazine. This product is intended for research and analytical applications. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity and can be used for toxoplasmosis research.
- It serves as an analytical standard.
- Intended for research and analytical applications.
- Possesses sulfonamide antibiotic properties.
- Demonstrates antimalarial activity.
- Suitable for toxoplasmosis research.
- Can be used in qualitative, quantitative, and methodological research experiments.
- Applicable in techniques such as HPLC, GC, and MS.
Medchemexpress LLC Sulfapyridine (Standard) | 144-83-2 | 99.9% | 50 MG
Sulfapyridine (Standard) is the analytical standard of Sulfapyridine, intended for research and analytical applications. It is a major metabolite of Sulfasalazine and acts as a sulfonamide antibiotic agent. This compound inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM, and also exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities. As an analytical standard, it is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard grade
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Possesses antibacterial, anti-inflammatory, and anti-rheumatic activities
Apexbio Technology LLC Sulfadiazine 68-35-9 5g
Sulfadiazine (CAS 68-35-9) is a small-molecule inhibitor targeting dihydropteroate synthase It is designed to inhibit microbial folate biosynthesis thereby disrupting folic acid synthesis required for pathogen proliferation Sulfadiazine exerts its biological activity primarily through the competitive inhibition of dihydropteroate synthase In in vitro studies Sulfadiazine demonstrates antiparasitic activity with IC50 values ranging from approximately 2 g/mL to 5 g/mL against Toxoplasma gondii depending on experimental conditions and parasite strains Based on these pharmacological properties Sulfadiazine holds research potential in antiparasitic activity evaluation and studies of folic acid metabolism pathways