Sulfonyls
Medchemexpress LLC Sulfathiazole | 72-14-0 | MFCD00005319 | 99.7% | 1 G
Sulfathiazole is an orally active endocrine disruptor that targets the steroidogenic pathway. It specifically enhances the activity of CYP19 in human adrenal cancer cells (H295R) and upregulates the mRNA expression of CYP17, CYP19, and 3β-HSD. It also increases the production of 17-estradiol (E2) and demonstrates endocrine disrupting effects on aquatic organisms like the Japanese medaka fish.
- Targets the steroidogenic pathway
- Enhances CYP19 activity in human adrenal cancer cells (H295R)
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases production of 17-estradiol (E2)
- Demonstrates endocrine disrupting effects on aquatic organisms
- Can inhibit copper corrosion in 0.1 M NaCl solution
- Increases plasma 17-estradiol concentrations in male Japanese medaka models
Medchemexpress LLC Sulfadiazine sodium | 547-32-0 | 98.0% | 5 G
Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity, utilized in toxoplasmosis research.
- Sulfonamide antibiotic with antimalarial activity
- Useful for toxoplasmosis research
- Purity of 98.0%
- Molecular formula: C10H9N4NaO2S
- Molecular weight: 272.26
- Appears as a white to off-white solid
- Store solid at 4°C, protected from light, under nitrogen
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Sulfapyridine | 144-83-2 | 99.85% | 10 G
Sulfapyridine is a sulfonamide antibiotic agent and a major metabolite of Sulfasalazine. It inhibits recombinant *P. carinii* dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. This compound also exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities.
- Sulfonamide antibiotic agent
- Major metabolite of Sulfasalazine
- Inhibits recombinant *P. carinii* dihydropteroate synthetase (DHPS)
- Exhibits antibacterial activity
- Exhibits anti-inflammatory activity
- Exhibits anti-rheumatic activities
Medchemexpress LLC Sulfadiazine (Standard) | 68-35-9 | 99.8% | 25 MG
Sulfadiazine (Standard) is the analytical standard of Sulfadiazine, intended for research and analytical applications. It is a sulfonamide antibiotic with antimalarial activity and can be used for toxoplasmosis research. This compound is the grade of analytical standard, which is the reference standard supplied assay.
- Analytical standard for Sulfadiazine
- Intended for research and analytical applications
- Sulfonamide antibiotic with antimalarial activity
- Can be used for toxoplasmosis research
- Used in qualitative research experiments in HPLC, GC, and MS
- Used in quantitative research experiments in HPLC, GC, and MS
- Used in methodological research experiments in HPLC, GC, and MS
eMolecules 41513-78-4 | Ambeed | 2-(13-Dioxoisoindolin-2-yl)benzoic acid | 1g | 573005493 | A869899 | MFCD00041218 | 267.24 | C15H9NO4
Ambeed | 2-Bromo-1-(33-dinitroazetidin-1-yl)ethan-1-one | 5mg | 534568145 | A400874 | 925206-65-1 | MFCD25976849 | 268.023 | C5H6BrN3O5
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Medchemexpress LLC Sulfapyridine (Standard) | 144-83-2 | 99.9% | 100 MG
Sulfapyridine (Standard) is an analytical standard intended for research and analytical applications. This compound is a major metabolite of Sulfasalazine and functions as a sulfonamide antibiotic agent, exhibiting antibacterial, anti-inflammatory, and anti-rheumatic activities. It serves as a reference standard for assays and is commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard for research and analytical applications
- Functions as a sulfonamide antibiotic agent
- Exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities
- Inhibits P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM
- Used in HPLC, GC, and MS research experiments
- Inhibits production of IL-8, CXCL1, and MCP-1 in synovial cells of rheumatoid arthritis
- Inhibits systemic allergic reactions in vivo
Medchemexpress LLC Sulfapyridine (Standard) | 144-83-2 | 99.9% | 25 MG
Sulfapyridine (Standard) is an analytical standard that serves as a sulfonamide antibiotic agent and a major metabolite of Sulfasalazine. It is intended for research and analytical applications. This compound exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities, and has been shown to inhibit recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. It is commonly used in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- Functions as an analytical standard.
- Acts as a sulfonamide antibiotic agent.
- Demonstrates antibacterial activity.
- Exhibits anti-inflammatory properties.
- Possesses anti-rheumatic activities.
- Inhibits P. carinii dihydropteroate synthetase.
- Suitable for HPLC, GC, and MS research.
eMolecules 122-11-2 | 4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide | Combi-Blocks | MFCD00057345 | 310.330 | C12H14N4O4S | 98.000 | COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 | 5g | 205386328
4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide | Combi-Blocks | 122-11-2 | MFCD00057345 | 310.330 | C12H14N4O4S | 98.000 | COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 | 5g | 205386328
Apexbio Technology LLC Sulfathiazole 72-14-0 10g
Sulfathiazole (CAS 72-14-0) is a small-molecule inhibitor targeting dihydropteroate synthase (DHPS) It is designed to competitively inhibit bacterial folic acid synthesis thereby disrupting the folate pathway and impeding microbial growth Sulfathiazole exerts its biological activity primarily through inhibition of DHPS In in vitro studies sulfathiazole demonstrates bacteriostatic inhibition with IC50 values ranging from low to medium micromolar concentrations depending on specific bacterial strains and experimental conditions Based on these pharmacological properties sulfathiazole holds research potential in investigating antibacterial resistance metabolic pathways of pathogens and enzyme-substrate interactions in microbiological and biochemical research
Medchemexpress LLC Sulfapyridine | 144-83-2 | MFCD00038036 | 99.9% | 1 G
Sulfapyridine is a sulfonamide antibiotic that is a major metabolite of Sulfasalazine. It acts as an antibiotic agent by inhibiting recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Beyond its antibacterial properties, Sulfapyridine also exhibits anti-inflammatory and anti-rheumatic activities.
- Inhibits IL-8, CXCL1, and MCP-1 production in synovial cells
- Active against Y. enterocolitica and Salmonella
- Significantly inhibits systemic allergic reactions in rats
- For research use only
Apexbio Technology LLC SULFATHIAZOLE-SODIUM-10G
Sulfathiazole sodium (CAS No 144-74-1) is commonly used in biomedical research as an antibacterial agent belonging to the sulfonamide class Originating from synthetic sulfonamide compounds it works by inhibiting bacterial folic acid synthesis through competitive antagonism of para-aminobenzoic acid (PABA) in the dihydropteroate synthase enzyme pathway Its in vitro activity is generally observed in the micromolar range against gram-positive and gram-negative bacteria It is frequently applied in various experimental models including cell cultures and animal studies to evaluate antibacterial efficacy and to screen for potential therapeutic effects Experimental concentrations typically depend on the specific research design
Revvity Health Sciences Inc HTRF Human CD47 / SIRP-α Binding Kit, 500 Assay Points
HTRF Human CD47 / SIRP-α Binding Kit, 500 Assay Points
