Sulfonyls
Apexbio Technology LLC Sulfadiazine 68-35-9 5g
Sulfadiazine (CAS 68-35-9) is a small-molecule inhibitor targeting dihydropteroate synthase It is designed to inhibit microbial folate biosynthesis thereby disrupting folic acid synthesis required for pathogen proliferation Sulfadiazine exerts its biological activity primarily through the competitive inhibition of dihydropteroate synthase In in vitro studies Sulfadiazine demonstrates antiparasitic activity with IC50 values ranging from approximately 2 g/mL to 5 g/mL against Toxoplasma gondii depending on experimental conditions and parasite strains Based on these pharmacological properties Sulfadiazine holds research potential in antiparasitic activity evaluation and studies of folic acid metabolism pathways
eMolecules Sulfadoxine | 2447-57-6 | 5G | Purity: 98%
Combi-Blocks | Sulfadoxine | 5G | 2447-57-6 | MFCD00792890
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Medchemexpress LLC Sulfadiazine-13C6 | 1189426-16-1 | 1 MG
Sulfadiazine-13C6 is a labeled Sulfadiazine, a sulfonamide antibiotic with antimalarial activity. This compound can be used as a tracer and as an internal standard for quantitative analysis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Sulfadiazine sodium | 547-32-0 | >98.0% | 1 ML
Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity, primarily used for toxoplasmosis research.
- Antimicrobial properties for various infections
- Effective in toxoplasmosis research
- Purity >98.0%
- White to off-white solid appearance
- Molecular weight of 272.26
- Chemical formula C10H9N4NaO2S
Apexbio Technology LLC Sulfathiazole 72-14-0 10mM (in 1mL DMSO)
Sulfathiazole (CAS 72-14-0) is a small-molecule inhibitor targeting dihydropteroate synthase (DHPS) It is designed to competitively inhibit bacterial folic acid synthesis thereby disrupting the folate pathway and impeding microbial growth Sulfathiazole exerts its biological activity primarily through inhibition of DHPS In in vitro studies sulfathiazole demonstrates bacteriostatic inhibition with IC50 values ranging from low to medium micromolar concentrations depending on specific bacterial strains and experimental conditions Based on these pharmacological properties sulfathiazole holds research potential in investigating antibacterial resistance metabolic pathways of pathogens and enzyme-substrate interactions in microbiological and biochemical research
eMolecules 4-Amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide | Combi-Blocks | 68-35-9 | MFCD00006065 | 250.280 | C10H10N4O2S | 98.000 | Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1 | 5g | 296391758
4-Amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide | Combi-Blocks | 68-35-9 | MFCD00006065 | 250.280 | C10H10N4O2S | 98.000 | Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1 | 5g | 296391758
eMolecules 4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide | Combi-Blocks | 122-11-2 | MFCD00057345 | 310.330 | C12H14N4O4S | 98.000 | COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 | 5g | 205386328
4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide | Combi-Blocks | 122-11-2 | MFCD00057345 | 310.330 | C12H14N4O4S | 98.000 | COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 | 5g | 205386328
Revvity Health Sciences Inc HTRF Human CD47 / SIRP-α Binding Kit, 500 Assay Points
HTRF Human CD47 / SIRP-α Binding Kit, 500 Assay Points
Medchemexpress LLC Sulfapyridine (Standard) | 144-83-2 | 99.9% | 25 MG
Sulfapyridine (Standard) is an analytical standard that serves as a sulfonamide antibiotic agent and a major metabolite of Sulfasalazine. It is intended for research and analytical applications. This compound exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities, and has been shown to inhibit recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. It is commonly used in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- Functions as an analytical standard.
- Acts as a sulfonamide antibiotic agent.
- Demonstrates antibacterial activity.
- Exhibits anti-inflammatory properties.
- Possesses anti-rheumatic activities.
- Inhibits P. carinii dihydropteroate synthetase.
- Suitable for HPLC, GC, and MS research.
Medchemexpress LLC Sulfapyridine (Standard) | 144-83-2 | 99.9% | 100 MG
Sulfapyridine (Standard) is an analytical standard intended for research and analytical applications. This compound is a major metabolite of Sulfasalazine and functions as a sulfonamide antibiotic agent, exhibiting antibacterial, anti-inflammatory, and anti-rheumatic activities. It serves as a reference standard for assays and is commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard for research and analytical applications
- Functions as a sulfonamide antibiotic agent
- Exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities
- Inhibits P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM
- Used in HPLC, GC, and MS research experiments
- Inhibits production of IL-8, CXCL1, and MCP-1 in synovial cells of rheumatoid arthritis
- Inhibits systemic allergic reactions in vivo
Medchemexpress LLC Sulfadiazine | 68-35-9 | 99.9%
Sulfadiazine is a sulfonamide antibiotic with antimalarial activity, primarily used for toxoplasmosis research.
- Functions as a sulfonamide antibiotic
- Exhibits antimalarial properties
- Utilized in toxoplasmosis research
- Demonstrates activity against Toxoplasma gondii in various cell lines (e.g., MRC5, Vero)
- Effectiveness evaluated in in vivo models against T. gondii strains
Medchemexpress LLC Sulfathiazole | 72-14-0 | MFCD00005319 | 99.7% | 1 G
Sulfathiazole is an orally active endocrine disruptor that targets the steroidogenic pathway. It specifically enhances the activity of CYP19 in human adrenal cancer cells (H295R) and upregulates the mRNA expression of CYP17, CYP19, and 3β-HSD. It also increases the production of 17-estradiol (E2) and demonstrates endocrine disrupting effects on aquatic organisms like the Japanese medaka fish.
- Targets the steroidogenic pathway
- Enhances CYP19 activity in human adrenal cancer cells (H295R)
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases production of 17-estradiol (E2)
- Demonstrates endocrine disrupting effects on aquatic organisms
- Can inhibit copper corrosion in 0.1 M NaCl solution
- Increases plasma 17-estradiol concentrations in male Japanese medaka models