Sulfoxides
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | 99.7% | 341.49 g·mol⁻¹ | C22H31NO2 | 10 MG
CB2R/FAAH modulator-3 is a small-molecule research compound that functions as a cannabinoid receptor 2 (CB2R) agonist and a fatty acid amide hydrolase (FAAH) inhibitor. Reported activity includes CB2R Ki = 20.1 nM, CB1R Ki = 67.6 nM, and FAAH IC50 = 3.4 μM. It is intended for preclinical studies of inflammatory signaling, neurodegeneration, cancer-related pathways, and infection-associated inflammatory responses.
- Dual activity as CB2R agonist and FAAH inhibitor.
- Reported high CB2R affinity (low nanomolar Ki).
- Lower affinity for CB1R supporting receptor selectivity.
- Applicable to studies of inflammation, neurodegeneration, and cancer biology.
- High chemical purity suitable for research use.
- Available in small-mass and solution formats for assay workflows.
Medchemexpress LLC Sirtuin modulator 3 5mg | 5mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Apexbio Technology LLC Sulforaphane(Synonyms: Broccoli sulforaphane, DL-Sulforaphane, R-Sulforaphane, 1-Isothiocyanato-4-(methylsulfinyl)butane), 50mg, CAS: 4478-93-7.
Sulforaphane (CAS 4478-93-7) is a naturally occurring isothiocyanate abundantly found in vegetables especially broccoli It acts primarily through activation of the Keap1-Nrf2 signaling pathway enhancing cellular defense against oxidative and electrophilic stress Sulforaphane has demonstrated antiproliferative activity in vitro as shown by dose-dependent cell cycle arrest at G2/M and apoptosis induction in HT29 human colon carcinoma cells Such effects involve elevated cyclin A and B1 levels increased pro-apoptotic Bax expression mitochondrial cytochrome c release and poly(ADP-ribose) polymerase cleavage These properties make sulforaphane relevant for investigating cancer chemoprevention and cellular stress responses
Medchemexpress LLC Perphenazine sulfoxide | 10078-25-8 | MFCD01702800 | 95.0% | 419.97 g/mol | C21H26ClN3O2S | 5 MG
Perphenazine sulfoxide is the sulphoxide metabolite of the antipsychotic perphenazine, formed by oxidation. Supplied as an analytical standard for laboratory research and analytical applications, this compound is intended for research use only and not for human or veterinary use. Common applications include metabolite identification, method development, and use as a reference material. CAS 10078-25-8; molecular weight 419.97 g/mol; formula C21H26ClN3O2S.
- Analytical standard suitable for chromatographic and spectrometric methods.
- Useful for metabolite identification and method validation.
- Provided as a solid reference material for laboratory use.
- Accompanied by quality documentation such as a certificate of analysis when available.
- Available in small weighed quantities appropriate for analytical workflows.
Medchemexpress LLC IL-17A modulator-1 | 2748749-29-1 | 98.8% | C33H31N5O4 | 25 MG
IL-17A modulator-1 is a compound that modulates the activity of IL-17A, an important cytokine involved in immune responses. Derived from patent WO2021239743+A1, this modulator inhibits the biological action of IL-17A with a pIC50 of 8.2, making it suitable for research into various diseases and disorders associated with IL-17A activity, including those with immune components, autoimmune pathologies, cancer, and neurodegenerative disorders. The product is provided as a white to off-white solid.
- Modulates IL-17A activity
- Inhibits biological action of IL-17A
- Suitable for research into immune, autoimmune, cancer, and neurodegenerative disorders
- White to off-white solid appearance
Medchemexpress LLC Glp-1r modulator l7-028 | 2648317-95-5 | 99.5% | C24H28N2O3 | 1 ML
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R through a transmembrane site, with an EC50 of 11.01 ± 2.73 μM.
- Allosteric modulator
- Enhances GLP-1 binding to GLP-1R via a transmembrane site
Medchemexpress LLC IL-17 modulator 3 | 2467731-88-8 | 99.51% | 579.73 | 1 ML
IL-17 modulator 3 is an IL-17 modulator that can be used for the research of inflammation, cancer, and autoimmune diseases. This product is for research use only and not sold to patients.
- Used for research of inflammation
- Used for research of cancer
- Used for research of autoimmune diseases
![Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287716.png-250.jpg)
Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG
Sirtuin modulator 6 is a small-molecule research compound that modulates sirtuin activity and is used in studies of lifespan, metabolic disorders, and neurodegenerative disease. The material is provided as a characterized solid with supporting batch documentation for research use in biochemical and cellular assays.
- High HPLC purity (99.7%).
- Molecular formula C22H19N3O3; molecular weight 373.40 g·mol⁻1.
- CAS registry number 476633-98-4 confirms chemical identity.
- Supplied in small research pack sizes suitable for assay preparation.
- Characterized by batch-specific COA and SDS for safety and quality data.
- Suitable for biochemical and cellular sirtuin pathway studies.
Medchemexpress LLC KAT modulator-1 (Compound 3) | 1314006-43-3 | 98.0% | 308.50 | C20H36O2 | 10 MG
KAT modulator-1 is a small-molecule modulator of lysine acetyltransferase (KAT) activity developed for epigenetics research. It has been shown to interact with full-length p300 but not with the isolated catalytic domain, making it a useful probe for studying KAT-protein interactions and regulatory mechanisms in biochemical and cell-based assays. The compound is supplied as a solid with documented storage recommendations and analytical data.
- Modulates lysine acetyltransferase (KAT) activity.
- Interacts with full-length p300 but not the catalytic domain.
- Suitable for biochemical and cell-based epigenetics studies.
- Supplied as a solid with defined storage stability.
- Molecular formula C20H36O2 and molecular weight 308.50.
- High chemical purity typically reported (about 98%).
Medchemexpress LLC (R)-IL-17 modulator 4 | 2446804-29-9 | 99.6% | C27H34N6O2 | 1 ML
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4. It is a proagent of IL-17 modulator 1, which is an orally active, highly efficacious IL-17 modulator. This product is promising for research into IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome. It is for research use only and not sold to patients.
- R-enantiomer of IL-17 modulator 4
- Functions as a proagent of IL-17 modulator 1
- Orally active and highly efficacious IL-17 modulator
- Potentially useful for research into IL-17A mediated diseases
- Supports studies on inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome
- For research use only
- High purity of 99.6%
- Molecular weight of 474.60
- Chemical formula C27H34N6O2
- Solid appearance
- Off-white to gray color
- Targets IL-17
Medchemexpress LLC Lithium dodecyl sulf 5g
Lithium dodecyl sulfate is an anionic detergent and surfactant that can be used in place of SDS for electrophoresis under low temperatures Lithium dodecyl sulfate can be used for synthesis of nanomaterials and chromatography[1]
Apexbio Technology LLC INCB024360 analogue 914471-09-3 10mM (in 1mL DMSO)
INCB024360 analogue (CAS 914471-09-3) is a selective inhibitor of indoleamine 2 3-dioxygenase 1 (IDO1) an enzyme responsible for initiating tryptophan catabolism along the kynurenine pathway IDO1-mediated depletion of tryptophan in the tumor microenvironment can suppress T-cell proliferation and promote immune tolerance facilitating cancer immune evasion INCB024360 analogue inhibits human IDO1 with an IC50 of 67 nM and demonstrates minimal activity against the related enzyme TDO In vivo studies in mouse melanoma models reveal dose-dependent anti-tumor activity and significant reductions in kynurenine levels supporting its utility as a research tool to investigate IDO1-targeted immunotherapy strategies
Medchemexpress LLC Il-17a modulator-3 | 2467732-95-0 | 99.4% | 639.80 | C34H50FN7O4 | 10 MG
Research-grade small molecule for in vitro investigation of IL-17A-related biology, including inflammation, cancer, and autoimmune disease pathways. Supplied as a solid with documented physicochemical properties, solubility, and storage recommendations to support reproducible experimental use.
- Modulates IL-17A activity in vitro, with reported IC50 < 10 μM.
- High chemical purity suitable for research applications.
- Molecular formula C34H50FN7O4 and molecular weight 639.80 Da.
- Soluble in DMSO at high concentration; ultrasonic assistance recommended.
- Recommended storage conditions defined for powder and solutions to preserve stability.
Medchemexpress LLC Sirtuin modulator 1 | 2070015-26-6 | 99.85% | 606.20 | 100 MG
Sirtuin modulator 1 is a compound that acts as a modulator of SIRTl, a homolog of SIRT3. This compound has an EC1.5 of less than 1 μM and was extracted from patent WO 2010071853 A1, Compound No.4.
- Modulator of SIRTl, a homolog of SIRT3
- High purity of 99.85%
- Solid appearance, light yellow to yellow color
- Molecular weight of 606.20
- Soluble in DMSO at 12.5 mg/mL