Sulfoxides
![Medchemexpress LLC 2(3h)-benzothiazolone, 6-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-3-methyl | 142477-34-7 | 97.1% | 383.51 g/mol | C21H25N3O2S | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214116.png-250.jpg)
Medchemexpress LLC 2(3h)-benzothiazolone, 6-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-3-methyl | 142477-34-7 | 97.1% | 383.51 g/mol | C21H25N3O2S | 1 MG
A selective small-molecule research ligand for the 5-HT1A serotonin receptor that also exhibits activity at adrenergic α1 and dopamine D2 receptors. Supplied as a white to off-white solid with supporting analytical documentation (COA and datasheet) for preclinical pharmacology and receptor profiling studies.
- High affinity for 5-HT1A receptor, IC50 ≈ 2 nM.
- Measured off-target activity at adrenergic α1 and dopamine D2 receptors (IC50 ≈ 10 nM and 40 nM).
- Supplied as a stable solid suitable for frozen or refrigerated storage.
- Certificate of analysis and purity data available to support assay reproducibility.
- Useful as a pharmacological tool for serotonin receptor profiling and CNS research.
Cayman Chemical Sulforaphane Inhibitors
An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells
Medchemexpress LLC D-galactose-6-O-sulfate sodium salt | 125455-62-1 | MFCD00078771 | 95.0% | 282.20 g/mol | C6H11NaO9S | 5 MG
D-Galactose-6-O-sulfate sodium salt is the sodium salt form of D-galactose 6-sulfate supplied as a biochemical reagent for life-science research. It is intended for use as a biological material or organic compound in laboratory assays and analytical applications where a sulfated galactose derivative is required.
- Used as a biochemical reagent for life-science research.
- Sodium salt form for improved aqueous solubility.
- High purity (95.0%).
- Suitable for use as a biological material or organic compound in assays.
- Available in milligram pack sizes for small-scale experiments.
- Identified by CAS 125455-62-1 and formula C6H11NaO9S.
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells
Cayman Chemical Sulindac sulfide
An active metabolite of sulindac; inhibits COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively); inhibits aldose reductase (IC50 = 279 nM), blocking NADPH-dependent reduction of glucose to sorbitol, and reducing type 2 diabetic complications; inhibits colorectal cancer growth in vitro and in vivo
TARGETMOL CHEMICALS INC ABEMACICLIB METABOLITE M 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer. purity: 98%