Sulfoxides
Medchemexpress LLC Cb2r/faah modulator-2 | 2876918-68-0 | 367.52 g·mol⁻¹ | C24H33NO2 | 10 MG
CB2R/FAAH modulator-2 is a research-grade small-molecule dual-target modulator that acts as an agonist at the cannabinoid CB2 receptor and an inhibitor of fatty acid amide hydrolase (FAAH). It is supplied as a solid for in vitro and in vivo pharmacology studies involving cannabinoid signaling and endocannabinoid metabolism. The compound has CAS 2876918-68-0, molecular formula C24H33NO2, and molecular weight 367.52 g·mol⁻¹.
- Dual CB2R agonist and FAAH inhibitor.
- Suitable for in vitro and in vivo pharmacology studies.
- Provided as a solid, with an option as 10 mM in DMSO solution.
- Available in small research sizes, for example 10 mg.
- CAS number 2876918-68-0 for unambiguous identification.
- Recommended storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
Medchemexpress LLC NR2F6 modulator-1 | 904449-84-9 | 99.5% | 419.45 | 25 MG
NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. This compound can be utilized for researching immune modulation and the modulation of cancer stem cell activity.
- Potent NR2F6 modulator
- Can be used for researching immune modulation
- Useful for modulation of cancer stem cell activity
- Appears as an off-white to light yellow solid
- Soluble in DMSO (125 mg/mL)
- In vivo solubility in 10% DMSO, 90% corn oil (≥ 2.08 mg/mL)
Medchemexpress LLC mGluR3 modulator-1 | 374548-18-2 | C16H21N3O | 5 MG
mGluR3 modulator-1 (compound 3) is a mGluR3 modulator with an EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay. It is intended for research use only.
- Solid, white to off-white appearance
- Purity of 98.67%
- Molecular weight: 271.36
- Can be stored as powder at -20°C for 3 years, or 4°C for 2 years
- Can be stored in solvent at -80°C for 6 months, or -20°C for 1 month
- Soluble in DMSO at 125 mg/mL
Medchemexpress LLC N'-(3-acetylphenyl)-N-(3-(2-methoxyethyl)-2,4-dioxo-1-(2-(piperidin-1-yl)ethyl)-1,2,3,4-tetrahydroquinazolin | 2946701-09-1 | 99.3% | 507.58 g/mol | C27H33N5O5 | 10 MG
COP1-ATGL modulator 1 is an orally active small-molecule research reagent that modulates the COP1-ATGL pathway. It increases ATGL protein expression, reduces ATGL and COP1 ubiquitination, and diminishes lipid accumulation in hepatocytes at nanomolar concentrations. Supplied as a white to off-white solid with high purity and defined storage recommendations for powder and solution.
- Orally active modulator of COP1-ATGL signaling.
- Increases ATGL protein expression at nanomolar concentrations.
- Reduces ATGL and COP1 ubiquitination in cellular assays.
- High purity suitable for research applications.
- Stable solid with recommended low-temperature storage.
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells