Sulfoxides
Medchemexpress LLC Cytochrome P450 24A1 Antibody (YA2121) | 10 UL
Cytochrome P450 24A1 Antibody (YA2121) is a non-conjugated, Rabbit-derived IgG monoclonal antibody, specifically designed to target Cytochrome P450 24A1. It is intended for research use only.
- Host: Rabbit
- Clonality: Recombinant, Monoclonal
- Species reactivity: Human
- Isotype: IgG
- Conjugation: Non-conjugated
- Formulation: Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
- Storage & stability: Stored at -20°C for 1 year, avoiding repeated freeze/thaw cycles.
- Applications: Western blot (WB) with a dilution ratio of 1:500-1:1000.
- Function: This cytochrome P450 monooxygenase is crucial for vitamin D catabolism and calcium homeostasis, inactivating calcidiol and calcitriol through C24- and C23-oxidation pathways.
- Subcellular localization: Mitochondrion
Aobchem Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 500mg
Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 500mg
Medchemexpress LLC Elafibranor sulfoxide | 95.0% | 400.49 | 25 MG
Elafibranor (GFT505) sulfoxide is a sulfoxide metabolite of Elafibranor (HY-16737). Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis.
- Purity: 95.0%
- Molecular weight: 400.49
- Formula: C22H24O5S
- Appearance: Solid
- Color: Light yellow to yellow
- Solubility (in vitro): 100 mg/mL (DMSO)
- Storage (powder): -20°C 3 years, 4°C 2 years
- Storage (in solvent): -80°C 6 months, -20°C 1 month
- Research use only
Cayman Chemical Sulindac Inhibitors
An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide; selective for COX-2 over COX-1 (IC50 = >1,000 µM); inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema in rats at 100 mg/kg; reduces tumor growth in a BxPC-3 mouse xenograft model at 60 mg/kg
Medchemexpress LLC Fast garnet GBC sulfate salt | 101-89-3 | MFCD00011883 | 90.0% | 334.35 g/mol | C14H14N4O4S | 250 MG
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase used to detect and visualize enzyme activity in histochemical and biochemical assays. It is supplied as a brown to black solid powder with a stated purity of 90% and is offered in multiple laboratory-scale pack sizes.
- Chromogenic substrate for alkaline phosphatase.
- Provides visible staining to localize enzymatic activity in tissue and cell samples.
- Supplied as a solid powder, brown to black in appearance.
- Stated purity of 90.0% supports consistent staining performance.
- Available in multiple laboratory pack sizes for flexible use.
- Molecular formula C14H14N4O4S, molecular weight 334.35 g/mol.
TARGETMOL CHEMICALS INC GSK2983559 ACTIVE METABO 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK2983559 active metabolite (RIPK2-IN-1) is a potent selective receptor-interacting protein-2 (RIP2) kinase inhibitor. purity: 98%
TARGETMOL CHEMICALS INC 5-HT1A MODULATOR 1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. 5-HT1A modulator 1 displays very high affinities for the 5-HT1A (alpha)1-adrenergic receptor and D2 receptor (IC50s = 2 nM 10 nM and 40 nM). purity: 99%
Medchemexpress LLC (E/Z)-Sulindac sulfide | 32004-67-4 | 99.88% | 50 MG
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. It can be used for researching Alzheimer's disease.
- Potent γ-secretase modulator (GSM)
- Selectively reduces Aβ42 production
- Used for researching Alzheimer's disease
Medchemexpress LLC IL-17A modulator-1 | 2748749-29-1 | 98.8% | C33H31N5O4 | 25 MG
IL-17A modulator-1 is a compound that modulates the activity of IL-17A, an important cytokine involved in immune responses. Derived from patent WO2021239743+A1, this modulator inhibits the biological action of IL-17A with a pIC50 of 8.2, making it suitable for research into various diseases and disorders associated with IL-17A activity, including those with immune components, autoimmune pathologies, cancer, and neurodegenerative disorders. The product is provided as a white to off-white solid.
- Modulates IL-17A activity
- Inhibits biological action of IL-17A
- Suitable for research into immune, autoimmune, cancer, and neurodegenerative disorders
- White to off-white solid appearance
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells
Medchemexpress LLC Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- | 2097787-75-0 | 99.0% | 308.40 | 5 MG
Nur77 modulator 3 (HY-162147) is a chemical compound intended for research use only. It has a molecular weight of 308.40 and exhibits a high purity of 99.01% via HPLC analysis. This compound is identified by its CAS Number 2097787-75-0 and the chemical name Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)-.
- Provided as a white to off-white solid
- Structure confirmed by ¹H NMR and LCMS
- High purity of 99.01% verified by HPLC
- Powder storage recommended at -20°C for up to 3 years
- In-solvent storage recommended at -80°C for 6 months or -20°C for 1 month
- Complies with specified quality standards
Medchemexpress LLC Sonidegib metabolite 25mg | 1221722-10-6 | 25 MG
Sonidegib metabolite M48 is the primary circulating metabolite of sonidegib, provided as a research-grade chemical for laboratory studies. The compound has formula C15H11F3O3, molecular weight 296.24 g·mol⁻¹, and is supplied with documented purity and storage recommendations for research use only.
- Research use only; not for human or clinical use.
- High reported purity: 98.0%.
- White to off-white solid suitable for analytical and in vitro studies.
- Available in small research quantities for assay development and metabolic studies.
- Stable at room temperature for up to 3 years under recommended storage conditions.
Medchemexpress LLC Sirtuin modulator 3 100mg | 100mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
