Sulfoxides
Medchemexpress LLC Glp-1r modulator l7-028 | 2648317-95-5 | 99.5% | C24H28N2O3 | 1 ML
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R through a transmembrane site, with an EC50 of 11.01 ± 2.73 μM.
- Allosteric modulator
- Enhances GLP-1 binding to GLP-1R via a transmembrane site
Medchemexpress LLC IL-17 modulator 1 (disodium) | 2446803-91-2 | 98.4% | C28H35N6Na2O6P | 25 MG
IL-17 modulator 1 disodium is an orally active, highly efficacious small molecule IL-17 modulator. It is designed for research into diseases such as psoriasis, ankylosing spondylitis, and psoriatic arthritis. The disodium salt form provides enhanced water solubility and stability, making it suitable for various research applications.
- Orally active and highly efficacious small molecule
- Enhanced water solubility and stability
- Useful for research into psoriasis
- Useful for research into ankylosing spondylitis
- Useful for research into psoriatic arthritis
Medchemexpress LLC Cytochrome P450 17A1 Antibody (YA478 | 57 kDa | 50 UL
The Cytochrome P450 17A1 Antibody (YA478) is a rabbit host antibody designed for research applications. It is supplied as a liquid with a concentration of 1.0 mg/mL and reacts with human, mouse, and rat samples.
- Reacts with human, mouse, and rat samples
- Suitable for Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, and Flow Cytometry
- Formulated in TBS (pH 7.4), 0.05% BSA, and 40% Glycerol
- Contains 0.05% Sodium Azide as a preservative
- Stable for 1 year when stored at -20°C
- Avoid repeated freeze/thaw cycles
eMolecules 67-68-5 | Dimethyl Sulfoxide | AA Blocks LLC | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 500g | 598385589
Dimethyl Sulfoxide | AA Blocks LLC | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 500g | 598385589
eMolecules 1193-82-4 | (Methylsulfinyl)benzene | Oakwood Chemicals | MFCD00002088 | 140.200 | C7H8OS | 95.000 | CS(=O)c1ccccc1 | 5g | 480156440
(Methylsulfinyl)benzene | Oakwood Chemicals | 1193-82-4 | MFCD00002088 | 140.200 | C7H8OS | 95.000 | CS(=O)c1ccccc1 | 5g | 480156440
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells
Medchemexpress LLC N,N,6-triethyl-9,10-didehydro-1-(1-oxopropyl)-ergoline-8β-carboxamide | 2648317-95-5 | 99.5% | C24H28N2O3 | 10MG
GLP-1R modulator L7-028 is a small-molecule positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R) that enhances GLP-1 binding via a transmembrane site. Supplied as a solid or as a 10 mM solution in DMSO for research use, it demonstrates activity in the low micromolar range and is provided with high purity.
- Enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM).
- High purity, approx. 99.5%.
- Available as solid and as 10 mM solution in DMSO.
- Soluble in DMSO at 100 mg/mL; ultrasonic recommended for dissolution.
- Stable under recommended storage: powder -20°C for long term; solution -80°C for extended storage.
- Intended for research use only; not for human or veterinary use.
Aobchem Methyl(4-phenethoxyphenyl)sulfane | 95% | C15H16OS | 1g
Methyl(4-phenethoxyphenyl)sulfane | 95% | C15H16OS | 1g
Aobchem 4-Fluoro-3-(methylsulfinyl)phenol | ≥95% | CAS 2734777-83-2 | C7H7FO2S | 1g
4-Fluoro-3-(methylsulfinyl)phenol | ≥95% | CAS 2734777-83-2 | C7H7FO2S | 1g
Medchemexpress LLC Iduronate 2-sulfatase (recombinant human) | 50936-59-9 | >95.0% | 100 UG
Recombinant human iduronate 2-sulfatase (IDS) expressed in HEK293 cells and supplied as a His-tagged, lyophilized protein for research use. IDS catalyzes removal of 2-sulfate groups from iduronate residues in glycosaminoglycans; the product includes documented purity, endotoxin, activity, and storage specifications to support biochemical and cell-based assays.
- Expressed in HEK293 cells for human-like glycosylation
- C-terminal His tag enables detection and purification
- Lyophilized from PBS (pH 7.4) for stability and convenient handling
- Purity greater than 95% by reducing SDS-PAGE
- Endotoxin level <1 EU/μg, suitable for many cell-based assays
- Specific activity 6.123 pmoL/min/μg measured with PNCS substrate
- Store at -20°C; aliquot and keep at -80°C for extended storage
Aobchem 4-Fluoro-3-(methylsulfinyl)phenol | ≥95% | CAS 2734777-83-2 | C7H7FO2S | 250mg
4-Fluoro-3-(methylsulfinyl)phenol | ≥95% | CAS 2734777-83-2 | C7H7FO2S | 250mg
Medchemexpress LLC Il-17a modulator-3 | 2467732-95-0 | 99.4% | 639.80 | C34H50FN7O4 | 10 MG
Research-grade small molecule for in vitro investigation of IL-17A-related biology, including inflammation, cancer, and autoimmune disease pathways. Supplied as a solid with documented physicochemical properties, solubility, and storage recommendations to support reproducible experimental use.
- Modulates IL-17A activity in vitro, with reported IC50 < 10 μM.
- High chemical purity suitable for research applications.
- Molecular formula C34H50FN7O4 and molecular weight 639.80 Da.
- Soluble in DMSO at high concentration; ultrasonic assistance recommended.
- Recommended storage conditions defined for powder and solutions to preserve stability.
Medchemexpress LLC 5-HT1A modulator 2 hydrochloride | 3880-76-0 | 99.69% | 213.70 | 10 MM * 1 ML
5-HT1A modulator 2 hydrochloride is a derivative of 8-OH-DPAT (HY-112061), acting as a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding.
- Modulator of 5-HT1A
- Derivative of 8-OH-DPAT
- Binding Ki of 53 nM for 5-HT1A