Sulfoxides
Medchemexpress LLC Sirtuin modulator 3 5mg | 5mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Medchemexpress LLC Sirtuin modulator 3 10mg | 10mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
eMolecules 110-01-0 | Tetrahydrothiophene | Oakwood Chemicals | MFCD00005476 | 88.170 | C4H8S | 98.000 | C1CCSC1 | 2.5kg | 480116242
Tetrahydrothiophene | Oakwood Chemicals | 110-01-0 | MFCD00005476 | 88.170 | C4H8S | 98.000 | C1CCSC1 | 2.5kg | 480116242
Medchemexpress LLC mGluR3 modulator-1 | 374548-18-2 | MFCD01957075 | 98.7% | 271.36 g·mol⁻1 | C16H21N3O | 10 MG
mGluR3 modulator-1 is a small-molecule modulator of the metabotropic glutamate receptor 3 (mGluR3) intended for research use. It demonstrates activity in cellular calcium mobilization assays (EC50 = 1-10 μM) and is supplied with a reported high purity and defined molecular properties suitable for in vitro pharmacology and receptor profiling studies.
- Modulates mGluR3 receptor activity in cell-based assays.
- Demonstrated EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 calcium mobilization assay.
- High purity suitable for research applications.
- Available in small mass packages for screening and assay work.
- Includes chemical identifiers for traceability, such as CAS 374548-18-2.
Medchemexpress LLC Triclabendazole sulfoxide (TCBZ-SO) | 100648-13-3 | 98.8% | 375.66 | 25 MG
Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole. It exhibits anti-parasite effects and can inhibit the membrane transporter ABCG2/BCRP.
- Main plasma metabolite of Triclabendazole
- Exhibits anti-parasite effects
- Inhibits the membrane transporter ABCG2/BCRP
- Useful in infection disease research
- Useful in cancer disease research
- Useful in parasitic infection research
Medchemexpress LLC Kv3 modulator 2 | 2101321-76-8 | 99.9% | 379.41 g·mol⁻¹ | C21H21N3O4 | 5 MG
Kv3 modulator 2 is a small-molecule modulator of Kv3 voltage-gated potassium channels with reported analgesic activity. It is provided for laboratory research use and is characterized by a defined molecular formula and molecular weight, and high purity suitable for preclinical studies.
- High purity (99.9%).
- Available in small research quantities (example: 5 mg).
- Molecular formula C21H21N3O4; molecular weight 379.41 g·mol⁻¹.
- Reported Kv3 channel modulatory activity with analgesic effects.
- For research use only; not for human or clinical use.
![Medchemexpress LLC 4-Thiazolecarboxamide, 5-(3-methoxypropyl)-2-phenyl-N-[2-[6-(1-pyrrolidinylmethyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]-,hydrochloride | 2070015-26-6 | 99.85% | 606.20 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403398-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Thiazolecarboxamide, 5-(3-methoxypropyl)-2-phenyl-N-[2-[6-(1-pyrrolidinylmethyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]-,hydrochloride | 2070015-26-6 | 99.85% | 606.20 | 25 MG
Sirtuin modulator 1 is a modulator of SIRTl, a homolog of SIRT3, with EC1.5 of < 1 μM. It was extracted from patent WO 2010071853 A1, Compound No.4.
- Modulates SIRTl, a homolog of SIRT3.
- Has an EC1.5 of less than 1 μM.
- Extracted from patent WO 2010071853 A1.
- Identified as Compound No.4 in the patent.
Medchemexpress LLC 3-isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-... | 1825371-51-4 | 99.8% | 446.54 | 1 MG
Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with an IC50 of 180 nM. This product is for research use only and not sold to patients.
- Selective inhibitor for Smad ubiquiquitination regulatory factor 1 (Smurf1).
- IC50 of 180 nM.
- For research use only.
- Appearance is a white to off-white solid.
- Specific storage conditions for powder and in solvent.
- Soluble in DMSO.
Medchemexpress LLC Hsp110/sGC-modulator-1 | 99.6% | 490.86 g·mol⁻1 | C24H18ClF3N2O4 | 10 MG
Hsp110/sGC-modulator-1 is an orally active small-molecule regulator that modulates Hsp110 and soluble guanylate cyclase (sGC). It demonstrates potent dual-target activity, produces vasodilatory effects, and attenuates pulmonary vascular remodeling and right ventricular hypertrophy in preclinical studies. Supplied in milligram quantities for research use only. Molecular formula C24H18ClF3N2O4; molecular weight 490.86 g·mol⁻1; reported purity 99.58%.
- Dual-target activity against Hsp110 and sGC.
- Demonstrated vasodilatory and antiproliferative effects in preclinical models.
- Suitable for in vitro and in vivo preclinical research.
- Supplied in milligram quantities for screening and lead optimization.
- Reported purity 99.58% and characterized by HRMS.
Medchemexpress LLC (E/Z)-Sulindac sulfide | 32004-67-4 | 99.9% | 1 ML
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. This product is designed for researching Alzheimer's disease.
- Potent γ-secretase modulator
- Selectively reduces Aβ42 production
- Favors shorter Aβ species
- Suitable for Alzheimer's disease research
Medchemexpress LLC KAT modulator-1 (Compound 3) | 1314006-43-3 | 98.0% | 308.50 | C20H36O2 | 10 MG
KAT modulator-1 is a small-molecule modulator of lysine acetyltransferase (KAT) activity developed for epigenetics research. It has been shown to interact with full-length p300 but not with the isolated catalytic domain, making it a useful probe for studying KAT-protein interactions and regulatory mechanisms in biochemical and cell-based assays. The compound is supplied as a solid with documented storage recommendations and analytical data.
- Modulates lysine acetyltransferase (KAT) activity.
- Interacts with full-length p300 but not the catalytic domain.
- Suitable for biochemical and cell-based epigenetics studies.
- Supplied as a solid with defined storage stability.
- Molecular formula C20H36O2 and molecular weight 308.50.
- High chemical purity typically reported (about 98%).