Sulfoxides
Medchemexpress LLC Mrgprx4 modulator-1 | 2492596-61-7 | 98.1% | C16H13ClF3NO3 | 10MG
MRGPRX4 modulator-1 is a small-molecule modulator of the Mas-related G-protein coupled receptor X4 used as a research tool for in vitro pharmacology and receptor signaling studies. It is supplied as a solid and as ready-to-use DMSO solutions, and is characterized by defined chemical identity, high purity, and documented storage recommendations.
- Modulates MRGPRX4 receptor activity in vitro.
- Available as solid and DMSO solution formats for flexible use.
- High purity suitable for research applications.
- Documented chemical identity (CAS 2492596-61-7) and formula C16H13ClF3NO3.
- Stable when stored under recommended conditions for extended shelf life.
Medchemexpress LLC A1AT modulator 1 | 2406205-61-4 | 99.8% | 370.42 | C21H23FN2O3 | 5 MG
A1AT modulator 1 is a research-grade small molecule inhibitor used to study Z α1-antitrypsin polymerization and related biochemical pathways. The compound is a solid (white to off-white) with molecular formula C21H23FN2O3 and molecular weight 370.42. It is provided for laboratory research use with storage recommendations for both powder and solution to maintain stability.
- Potent inhibitor of Z α1-antitrypsin polymerization (pIC50 = 8.3).
- High analytical purity (99.77%).
- Solid, white to off-white appearance suitable for handling in lab settings.
- Stable when stored under recommended conditions (powder: -20°C or 4°C; in solvent: -80°C or -20°C).
- Provided in small-quantity packaging appropriate for research assays.
Medchemexpress LLC 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1-(2-phenylethyl)- | 421578-93-0 | 99.8% | 371.43 g·mol⁻¹ | C24H21NO3 | 5 MG
GLP-1R modulator C5 is a small-molecule allosteric modulator that enhances GLP-1 binding to the GLP-1 receptor via a transmembrane site. It shows in vitro activity (EC50 1.59 ± 0.53 μM) and is provided for research applications with supporting characterization and handling data.
- Allosteric enhancement of GLP-1 binding (EC50 1.59 ± 0.53 μM).
- High reported purity of 99.81%.
- Molecular formula C24H21NO3; molecular weight 371.43 g·mol⁻¹.
- Soluble in DMSO at 50 mg/mL; ultrasonic assistance recommended.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).
- Available in multiple small package sizes suitable for laboratory testing.
Medchemexpress LLC CRBN modulator-1 | 2407829-65-4 | 98.0% | 324.29 | 25 MG
CRBN modulator-1 is a Thalidomide analog and a CRBN modulator, extracted from WO2020006262A1, compound 10. It has an IC₅₀ of 3.5 μM and a Kᵢ of 0.98 μM. This product is for research use only.
- Thalidomide analog and CRBN modulator.
- IC₅₀ of 3.5 μM.
- Kᵢ of 0.98 μM.
- For research use only.
Medchemexpress LLC Cytochrome P450 17A1 Antibody (YA478) | 57 kDa | 100 UL
The Cytochrome P450 17A1 Antibody (YA478) from MedChemExpress is a rabbit-derived monoclonal antibody identified for laboratory research. Supplied as a liquid, it is stable under recommended storage conditions and formulated with TBS, BSA, glycerol, and sodium azide. This antibody is suitable for detecting Cytochrome P450 17A1 in human, mouse, and rat samples.
- Predicted and observed band size of 57 kDa
- Suitable for Western blot (WB), immunocytochemistry/immunofluorescence (ICC/IF), immunohistochemistry-paraffin (IHC-P), and flow cytometry (FC)
- Supplied at a concentration of 1.0 mg/mL
- Store at -20°C for up to 1 year
- Shipped with blue ice
Medchemexpress LLC N-(4-(4-(2-methoxyethoxy)phenyl)thiazol-2-yl)isoxazole-5-carboxamide | 2375779-31-8 | 99.3% | 345.37 g/mol | C16H15N3O4S | 10 MG
GP130 modulator-1 (compound A33) is a small-molecule modulator of the gp130 signaling pathway intended for research use in studies of inflammatory and degenerative disorders.
- Small-molecule gp130 signaling pathway modulator for research use.
- High purity: 99.3%.
- Molecular weight 345.37 g/mol.
- Chemical formula C16H15N3O4S.
- Available in multiple pack sizes, including 10 mg.
- Supplied as a light yellow to yellow solid for laboratory handling and storage.
TARGETMOL CHEMICALS INC SULINDAC SULFIDE 10MG
Also available in 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 uM. It is an active metabolite of sulinic acid. purity: 99%
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 10MM/1ML
GLP-1R modulator C16 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site.
- Enhances GLP-1 binding to GLP-1R
- Operates via a transmembrane site
- Purity of 98.7%