Sulfoxides
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells
Medchemexpress LLC Fast garnet GBC sulfate salt | 101-89-3 | MFCD00011883 | 90.0% | 334.35 g/mol | C14H14N4O4S | 250 MG
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase used to detect and visualize enzyme activity in histochemical and biochemical assays. It is supplied as a brown to black solid powder with a stated purity of 90% and is offered in multiple laboratory-scale pack sizes.
- Chromogenic substrate for alkaline phosphatase.
- Provides visible staining to localize enzymatic activity in tissue and cell samples.
- Supplied as a solid powder, brown to black in appearance.
- Stated purity of 90.0% supports consistent staining performance.
- Available in multiple laboratory pack sizes for flexible use.
- Molecular formula C14H14N4O4S, molecular weight 334.35 g/mol.
Cell Signaling Technology Mitochondrial Fusion Promoter M1 25 mg
Mitochondrial Fusion Promoter M1 25 mg
Cayman Chemical Sulindac Inhibitors
An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide; selective for COX-2 over COX-1 (IC50 = >1,000 µM); inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema in rats at 100 mg/kg; reduces tumor growth in a BxPC-3 mouse xenograft model at 60 mg/kg
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | 99.7% | 341.49 g·mol⁻¹ | C22H31NO2 | 10 MG
CB2R/FAAH modulator-3 is a small-molecule research compound that functions as a cannabinoid receptor 2 (CB2R) agonist and a fatty acid amide hydrolase (FAAH) inhibitor. Reported activity includes CB2R Ki = 20.1 nM, CB1R Ki = 67.6 nM, and FAAH IC50 = 3.4 μM. It is intended for preclinical studies of inflammatory signaling, neurodegeneration, cancer-related pathways, and infection-associated inflammatory responses.
- Dual activity as CB2R agonist and FAAH inhibitor.
- Reported high CB2R affinity (low nanomolar Ki).
- Lower affinity for CB1R supporting receptor selectivity.
- Applicable to studies of inflammation, neurodegeneration, and cancer biology.
- High chemical purity suitable for research use.
- Available in small-mass and solution formats for assay workflows.
Medchemexpress LLC Ramelteon metabolite M-II-d3 | 1246812-22-5 | 99.8% | 278.36 g/mol | C16H18D3NO3 | 5 MG
Ramelteon metabolite M-II-d3 is the deuterium-labeled analog of the major human metabolite of ramelteon, provided as a high-purity reference standard intended for use as a tracer or internal standard in quantitative analytical methods. It is supplied as a solid suitable for laboratory analysis.
- Deuterium-labeled internal standard for quantitative analysis.
- High purity suitable for analytical work.
- Supplied as a white to off-white solid for ease of handling.
- Compatible with NMR, GC-MS, and LC-MS workflows.
- Molecular weight approximately 278.36 g/mol for accurate calculations.
TARGETMOL CHEMICALS INC ABEMACICLIB METABOLITE M 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer. purity: 98%