Thioureas

Organosulfur compounds that have a thiocarbonyl functional group bonded to a nitrogen atom at each side and each nitrogen is bonded to a carbon atom; they are structurally similar to urea, except that the oxygen atom is replaced by a sulfur atom.

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226 – 240 of 262 results

226

AdipoGen PK 11195

Chemical. CAS 85532-75-8. Formula C21H21ClN2O. MW 352.9. Selective peripheral benzodiazepine antagonist. Apoptosis enhancer. Glucose-induced insulin secretion inhibitor. Induces mitochondria cytochrome c release. Anticancer compound. Antiproliferative. Pharmacological tool in autophagy.

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227

AdipoGen Pifithrin-alpha HBr

Chemical. CAS 63208-82-2. Formula C16H18N2OS . HBr. MW 286.4 . 80.9. p53 inhibitor. Reversibly blocks p53-dependent transcriptional activation. Tool to combat side effects of cancer therapy. Apoptosis inhibitor.

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228

Biomatik Corporation Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7

Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7

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229

AdipoGen Necrostatin-5 Nec-5

Chemical. CAS 337349-54-9. Formula C19H17N3O2S2. MW 383.5. Necroptosis inhibitor. Indirect RIP1 kinase inhibitor. Cardioprotective

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230

AdipoGen PP2

Chemical. CAS 172889-27-9. Formula C15H16ClN5. MW 301.8. Highly potent and selective Scr family tyrosine kinase inhibitor. Reduces cancer metastasis. Apoptotic. Antitumor compound. RIP2 inhbitor. Blocks TGF-beta-mediated cellular responses. Autophagy modulator.

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231

AdipoGen Z-Leu-Leu-Phe-CHO

Chemical. CAS 133429-58-0. Formula C29H39N3O5. MW 509.7. Reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC.

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232

AdipoGen Elbasvir

Chemical. CAS 88321-09-9. Formula C17H30N2O5. MW 342.4. Aloxistatin is a cell permeable irreversible inhibitor of lysosomal and cytosolic cysteine proteases cathepsin B an L, calpain 1/2, papain and has diverse biological activities. It is an ethyl ester form of E-64c that inhibits calpain and the cysteine proteases cathepsins F, K, B, H, and L.

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233

AdipoGen Alsterpaullone

Chemical. CAS 237430-03-4. Formula C16H11N3O3. MW 293.3. Potent CDK1/cyclin B IC50 = 35 nM inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E IC50 = 200 nM, CDK5/p25 IC50 = 40 nM, CDK5/p35 IC50 = 40 nM. GSK-3beta glycogen synthase kinase-3beta inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor.

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234

AdipoGen Desacetylcolchicine tartrate

Chemical. CAS 49720-72-1. Formula C20H23NO5 . C4H6O6. MW 357.4 . 150.1. Synthetic. Anticancer colchicine analog. Microtubule polymerization inhibitor. Prevents cell division.