Thioureas
AdipoGen Boc-Leu-Arg-Arg-AMC
Chemical. CAS 109358-46-5 free base. Formula C33H52N10O7 . C2H4O2. MW 700.8 . 60.1. Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. Substrate for the Kex2 endopeptidase from S. Cervisiae, which has substrate specificity toward the C-terminal side of LR, PR and RR sequences. Can be cleaved by Kallikrein 5 with a P1 site preference for basic residues R and K. Excitation 380nm. Emission 460nm. This substrate is useful for inhibitor screening and kinetic analysis.
Sigma Organic Chemistry N N-Dibutylthiourea | 100G | 109-46-6 | MFCD00004926
N,N'-Dibutylthiourea, 100G
About This Item:
Linear Formula: CH3(CH2)3NHCSNH(CH2)3CH3
Storage: room temp
EINECS Number: 203-674-6
![Sigma Aldrich Fine Chemicals Biosciences [beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin >=93% (HPLC), solid | 77327-45-8 | MFCD00135712 | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501769998.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences [beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin >=93% (HPLC), solid | 77327-45-8 | MFCD00135712 | 1MG
[beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin >=93% (HPLC), solid | Purity: >=93% (HPLC) | Mol Wt: 1075.3 | 77327-45-8 | MFCD00135712 | 1MG
eMolecules 6-Benzyl-2-thiouracil | 6336-50-1 | MFCD00023224 | 500mg
Toronto Research Chemicals | 6-Benzyl-2-thiouracil | 500mg | 601590344 | B315158 | | 6336-50-1 | MFCD00023224 | 218.270 | C11H10N2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules (2-Hydroxyphenyl)thiourea | 1520-26-9 | MFCD00041159 | 1g
Combi-Blocks | (2-Hydroxyphenyl)thiourea | 1g | 232333878 | SH-5742 | 98.000 | 1520-26-9 | MFCD00041159 | 168.210 | C7H8N2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules 2-Mercapto-3-phenylquinazolin-4-one | 18741-24-7 | MFCD00023895 | 100mg
Oakwood Chemical | 2-Mercapto-3-phenylquinazolin-4-one | 100mg | 537713488 | 189306 | | 18741-24-7 | MFCD00023895 | 254.310 | C14H10N2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
AdipoGen 1-Methyltryptamine
Chemical. CAS 7518-21-0. Formula C11H14N2. MW 174.24. Synthetic. Deacetylase inhibitor.
AdipoGen 4-Methylumbelliferone
Chemical. CAS 90-33-5. Formula C10H8O3. MW 176.17. 4-Methylumbelliferone 4-MU is a selective inhibitor of hyaluronan HA by depletion of UDP-glucuronic acid, the common substrate for HA synthesis and downregulation of hyaluronan synthase 2 and 3, MMP2 and MMP9. Since hyaluronan HA is a major component of the extracellular matrix that is synthesized in excess in cancer tissues, 4-MU has been shown to have anti-cancer activity and is involved in angiogenesis, invasion and metastasis of cancer. Fluorescent pH indicator, that is highly fluorescent in alkaline solution. Exhibits a blue fluorescence at pH7. The fluorescence intensity is pH dependent and increases to a maximum at pH10 plateau above pH10. The fluorescence at pH10.3 is approximately 100 times as intense as at pH7. Spectral data lambdaex=360nm lambdaem=448nm pH > 9.
AdipoGen Josamycin
Chemical. CAS 16846-24-5. Formula C42H69NO15. MW 827.99. Synthetic. A member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. May overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein Pgp. An antimicrobial against a wide variety of pathogens.
AdipoGen LY2835219
Chemical. CAS 1231930-82-7. Formula C27H32F2N8 . CH4O3S. MW 602.7. LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 CDK4 and CDK6 IC50s = 2 and 10 nM, respectively. Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.
AdipoGen 7b-OH-cholesteryl-bishemisucci
Chemical. CAS 105449-93-2. Formula C35H54O8 . 2C2H7NO. MW 602.80 . 61.08. Synthetic Water-soluble derivatives of 7beta-hydroxycholesterol. Anticancer compound, inducing apoptosis in various solid tumor cell lines.
AdipoGen 4-Hydroxytamoxifen
Chemical. CAS 68392-35-8. Formula C26H29NO2. MW 387.51. 4-Hydroxytamoxifen is an active metabolite of the chemotherapeutic drug tamoxifen, a selective estrogen receptor modulator SERM that acts as an agonist or antagonist in various tissues. 4-Hydroxytamoxifen acts as a tissue-selective agonist-antagonist of the estrogen receptors ERalpha and ERbeta. 4-Hydroxytamoxifen is an isoform-specific inhibitor of orphan estrogen-receptor-related ERR nuclear receptors beta and gamma. 4-Hydroxytamoxifen exhibits anticancer chemotherapeutic activity, inducing autophagy and vacuole formation as well as KRAS degradation in various cancer cell lines. In cardiac myocytes, 4-hydroxytamoxifen decreases Ca2 amplitude, slowing relaxation and decreasing contractility. 4-Hydroxytamoxifen has also shown to be a potent inhibitor of the mitochondrial permeability transition MPT.
AdipoGen 7-OH-4-methyl-21H-quinolone
Chemical. CAS 20513-71-7. Formula C10H9NO2. MW 175.18. Synthetic. 7-Hydroxy-4-methyl-21H-quinolone is a starting material for the synthesis of a potential cytotoxic compound class with activity against human tumor cell lines.
AdipoGen 6-Dimethylaminopurine
Chemical. CAS 938-55-6. Formula C7H9N5. MW 163.18. Synthetic. A puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-alpha upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B IC50 = 300 µM. Induces apoptosis in S-phase-arrested HeLa cells ~5 mM.
eMolecules AstaTech / 11-DIMETHYL-THIOUREA / 0.25g / 402181171 / F19159 / 95.000 / 6972-05-0 / MFCD00060474 / 104.170 / C3H8N2S
AstaTech / 11-DIMETHYL-THIOUREA / 0.25g / 402181171 / F19159 / 95.000 / 6972-05-0 / MFCD00060474 / 104.170 / C3H8N2S