Thioureas
AdipoGen Desacetylcolchicine tartrate
Chemical. CAS 49720-72-1. Formula C20H23NO5 . C4H6O6. MW 357.4 . 150.1. Synthetic. Anticancer colchicine analog. Microtubule polymerization inhibitor. Prevents cell division.
AdipoGen GSH-OEt
Chemical. CAS 92614-59-0. Formula C12H21N3O6S. MW 335.38. Synthetic. GSH-OEt is cellpermeable and has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. GSH-OEt is a protective agent against cellular damage, such as cataracts and mitochondrial degeneration. It undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Glutathione monoethyl ester may be used to supplement cellular pools of GSH in vitro and in vivo and can prevent ROS formation, neutralize toxic products and block apoptosis pathway. The effect of glutathione GSH and glutathione ethyl ester GSH-OEt supplementation on GSH homeostasis and exercise-induced oxidative stress was also examined. Glutathione ethyl ester protects against cisplatin-induced ototoxicity in the rat.
AdipoGen Z-Leu-Leu-Leu-BOH2 MG-262
Chemical. CAS 179324-22-2. Formula C25H42BN3O6. MW 491.4. Highly potent and selective cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome. Calpain and cathepsin inhibitor. Autophagy activator. Similar structure as MG-132 AG-CP3-0011 but much higher potency.
Biomatik Corporation Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7
Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7
eMolecules Chem-Impex Thiourea 100kg 112439619 00284 0 000 62-56-6 MFCD00008067 76 120 CH4N2S
Chem-Impex Thiourea 100kg 112439619 00284 0 000 62-56-6 MFCD00008067 76 120 CH4N2S
AdipoGen Ozagrel
Chemical. CAS 82571-53-7. Formula C13H12N2O2. MW 228.2. Synthetic. Ozagrel, an antithrombic drug, is a potent and selective TXA Synthase thromboxane A2 TXAS inhibitor. Acts as a selective inhibitor of TXAS with an IC50=11nM. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke, and antihypertensive effects in spontaneously hypertensive rats.
eMolecules Oakwood Chemicals Thiourea ACS Reagent Grade 25g 480154135 103320 62-56-6 MFCD00008067 76.120 CH4N2S
Oakwood Chemicals Thiourea ACS Reagent Grade 25g 480154135 103320 62-56-6 MFCD00008067 76.120 CH4N2S
AdipoGen L-Alanyl-L-glutamine
Chemical. CAS 39537-23-0. Formula C8H15N3O4. MW 217.22. Synthetic. L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine Ala-Gln and Gylcyl-L-glutamine Gly-Gln are used in cell culture media as alternative delivery forms of stabilized L-glutamine. Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals, cosmetics and food products. Alanyl-glutamine also acts as an antioxidant peroxide and anti-apoptosis LPS-induced factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro. Shown to improve intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy.
AdipoGen L-Alanyl-L-glutamine
Chemical. CAS 39537-23-0. Formula C8H15N3O4. MW 217.22. Synthetic. L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine Ala-Gln and Gylcyl-L-glutamine Gly-Gln are used in cell culture media as alternative delivery forms of stabilized L-glutamine. Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals, cosmetics and food products. Alanyl-glutamine also acts as an antioxidant peroxide and anti-apoptosis LPS-induced factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro. Shown to improve intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy.
eMolecules Chem-Impex Thiourea 1kg 386903162 30059 0 000 62-56-6 MFCD00008067 76 120 CH4N2S
Chem-Impex Thiourea 1kg 386903162 30059 0 000 62-56-6 MFCD00008067 76 120 CH4N2S
AdipoGen PTACH
Chemical. CAS 848354-66-5. Formula C20H26N2O2S2. MW 390.56. Synthetic. Non-hydroxamate HDAC inhibitor HDACi IC50 32, 48 and 41nM for HDAC4, HDAC1 and HDAC6, respectively. Cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor. Predicted to exhibit a similar HDAC binding mode as that of SAHA, interacting with the active-site zinc targeting group. Shown to exhibit comparable antiproliferative and apoptotic activity as SAHA against various cancer cell lines. Inhibits growth of various cancer cells in vitro EC50 = 1.1 - 9.1mM. Also reactivates latent HIV-1 gene expression.
AdipoGen Zoxamide
Chemical. CAS 156052-68-5. Formula C14H16Cl3NO2. MW 336.6. Synthetic. Fungicide. Primarily an oomycete fungicide although it has some activity against ascomycetes and basidiomycetes. The product acts by disruption of the microtubule structure and inhibition of cell division. The mechanism for this activity is through the covalent binding of the active ingredient to beta-tubulin in the cytoskeleton. Scanning microscopy studies showed zoxamide action against blight on potato crops begins after germination, achieving inhibition of hyphal development and sporangia production. This novel mode of action makes zoxamide an important new tool in antiresistance strategies. Can be used as a reference compound.
AdipoGen Zoxamide
Chemical. CAS 156052-68-5. Formula C14H16Cl3NO2. MW 336.6. Synthetic. Fungicide. Primarily an oomycete fungicide although it has some activity against ascomycetes and basidiomycetes. The product acts by disruption of the microtubule structure and inhibition of cell division. The mechanism for this activity is through the covalent binding of the active ingredient to beta-tubulin in the cytoskeleton. Scanning microscopy studies showed zoxamide action against blight on potato crops begins after germination, achieving inhibition of hyphal development and sporangia production. This novel mode of action makes zoxamide an important new tool in antiresistance strategies. Can be used as a reference compound.
Indofine Chemical THIOUREA, Products for Life Science, 62-56-6, 1 kg
THIOUREA, Products for Life Science, 62-56-6, 1 kg
eMolecules 2-Mercapto-6-phenylpyrimidin-4(3h)-one | 36822-11-4 | MFCD00847526 | 1g
Combi-Blocks, Inc. | 2-Mercapto-6-phenylpyrimidin-4(3h)-one | 1g | 569293205 | QK-4183 | 95.000 | 36822-11-4 | MFCD00847526 | 204.250 | C10H8N2OS
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