Anthracyclines
Doxorubicin hydrochloride
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Doxorubicin hydrochloride, MP Biomedicals™
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Daunorubicin hydrochloride
CAS: 23541-50-6 Molecular Formula: C27H30ClNO10 Molecular Weight (g/mol): 563.984 MDL Number: MFCD04974507 InChI Key: GUGHGUXZJWAIAS-QQYBVWGSSA-N Synonym: daunorubicin hydrochloride,daunorubicin hcl,daunomycin hydrochloride,daunoblastina,rubidomycin hydrochloride,daunorubicinol hydrochloride,daunoblastin,rubomycin,ondena,daunomycin chlorohydrate PubChem CID: 62770 IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Doxorubicin Hydrochloride 95.0+%, TCI America™
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Daunorubicin Hydrochloride 98.0+%, TCI America™
CAS: 23541-50-6 Molecular Formula: C27H30ClNO10 Molecular Weight (g/mol): 563.984 MDL Number: MFCD04974507 InChI Key: GUGHGUXZJWAIAS-QQYBVWGSSA-N Synonym: daunorubicin hydrochloride,daunorubicin hcl,daunomycin hydrochloride,daunoblastina,rubidomycin hydrochloride,daunorubicinol hydrochloride,daunoblastin,rubomycin,ondena,daunomycin chlorohydrate PubChem CID: 62770 IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Medchemexpress LLC Daunorubicin hydrochloride | 23541-50-6 | MFCD04974507 | 99.7% | 563.98 g/mol | C27H30ClNO10 | 5 MG
Daunorubicin hydrochloride is an anthracycline antibiotic and potent cytotoxic research compound that intercalates DNA and inhibits topoisomerase II. Provided as the hydrochloride salt for research use, it is commonly used in oncology and biochemical studies where controlled, small-quantity reagent handling and high-purity material are required.
- Anthracycline antibiotic with cytotoxic activity.
- Potent topoisomerase II inhibitor causing DNA intercalation.
- Hydrochloride salt form for enhanced solubility and handling.
- High purity suitable for analytical and biological assays.
- Molecular weight 563.98 g/mol; formula C27H30ClNO10.
- Supplied in small measured quantities for research workflows.
Medchemexpress LLC Doxorubicin hydrochloride | 25316-40-9 | MFCD00077757 | 99.3% | 579.98 g/mol | C27H30ClNO11 | 10 MG
Doxorubicin hydrochloride is an anthracycline antibiotic with cytotoxic activity supplied as a high-purity analytical standard for laboratory research. It functions as a DNA intercalator and inhibits topoisomerases I and II, making it useful as a biochemical reagent and reference in cell-based assays and analytical method development.
- High purity (99.33%) suitable for analytical applications.
- Confirmed identity: CAS 25316-40-9, molecular weight 579.98 g/mol.
- Available in multiple package sizes, including 10 mg.
- Acts as a DNA intercalator and topoisomerase I/II inhibitor.
- Suitable for biochemical assays, cell-based studies, and analytical standards.
AdipoGen Doxorubicin hydrochloride
Chemical. CAS 25316-40-9. Formula C27H29NO11 . HCl. MW 579.98. Doxorubicin, a broad spectrum anthracycline antibiotic, inhibits DNA and RNA synthesis in mammalian cells and has been shown to be a very effective anti-tumor agent. Doxorubicin binds to nucleic acids by intercalating the DNA double helix and stabilizing topoisomerase II cleavage complexes, leading to DNA strand breaks at specific doxorubicin-induced sites and formation of reactive oxygen species ROS in cells. It also been shown to evict histones leading to chromatin damage. Doxorubicin induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein and has been shown to have immunosuppressive properties. DOX can reduce mitochondrial NADH accumulation and impair oxidative phosphorylation in heart tissues, events associated with reduced glucose uptake.
TARGETMOL CHEMICALS INC DAUNORUBICIN HYDROCHLORI 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Daunorubicin hydrochloride (Rubidomycin hydrochloride) an anthracycline aminoglycoside antineoplastic inhibits DNA replication and repair and RNA and protein synthesis. purity: 99%
Medchemexpress LLC BIIE-0246 hydrochloride | 246146-55-4 | MFCD04113026 | >98.0% | 896.0 g/mol | C49H57N11O6 | 5 MG
BIIE-0246 hydrochloride is a selective, non-peptide antagonist of the neuropeptide Y Y2 receptor supplied as the hydrochloride salt for research use. It is used in pharmacological studies to probe NPY-mediated signaling and is provided at high purity for in vitro and in vivo experiments.
- Selective NPY Y2 receptor antagonist
- High purity (>98.0%) suitable for research
- Hydrochloride salt for improved aqueous solubility
- Molecular formula C49H57N11O6; molar mass 896.0 g/mol
- Available in small research pack sizes, for example 5 MG
Sigma Aldrich Fine Chemicals Biosciences Doxorubicin hydrochloride50MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Sigma Aldrich Fine Chemicals Biosciences Daunorubicin hydrochloride >=90% (HPLC) | 23541-50-6 | MFCD04974507 | 5MG
Daunorubicin hydrochloride >=90% (HPLC) | Purity: >=90% (HPLC) | Mol Wt: 563.98 | 23541-50-6 | MFCD04974507 | 5MG
Alkali Scientific Doxorubicin Hydrochloride, Powder, 50 Mg
Doxorubicin Hydrochloride (powder form, 50 mg) is a chemotherapy drug used for the treatment of a wide range of cancers, including breast cancer, leukemia, and lymphomas. The compound works by inhibiting DNA and RNA synthesis, effectively inducing apoptosis in rapidly dividing cells. In powder form, this drug is easy to reconstitute for precise dosing and flexible usage in both clinical and research environments. Doxorubicin is one of the most effective anticancer agents, often used in combination with other chemotherapies to maximize treatment efficacy. It is a key component in various chemotherapy regimens aimed at targeting aggressive and resistant cancer types.