Cinnamic acids and derivatives
Medchemexpress LLC Cinnamic acid | 621-82-9 | MFCD00004369 | 148.16 | 500 MG
Cinnamic acid is a chemical compound with potential applications in cancer intervention. It has shown dose-dependent growth inhibition in various tumor cells, including glioblastoma, melanoma, prostate, and lung carcinoma cells, with IC50 values ranging from 1 to 4.5 mM.
- Potential use in cancer intervention.
- Exhibits dose-dependent growth inhibition in tumor cells.
- Induces morphological changes consistent with melanocyte differentiation.
- Causes a dose-dependent loss of invasive capacity in treated tumor lines.
- Effective in glioblastoma, melanoma, prostate, and lung carcinoma cells.
eMolecules 4-(4'-Fluorobenzyloxy)phenylboronic acid | 871125-82-5 | MFCD07784403 | 25g
Combi-Blocks, Inc. | 4-(4'-Fluorobenzyloxy)phenylboronic acid | 25g | 603141609 | BB-8098 | 95.000 | 871125-82-5 | MFCD07784403 | 246.040 | C13H12BFO3
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eMolecules 4-(3'-Fluorobenzyloxy)phenylboronic acid | 1072951-98-4 | MFCD08276970 | 5g
Combi-Blocks, Inc. | 4-(3'-Fluorobenzyloxy)phenylboronic acid | 5g | 603141610 | BB-8208 | 98.000 | 1072951-98-4 | MFCD08276970 | 246.040 | C13H12BFO3
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Medchemexpress LLC Trans-Cinnamic acid | 140-10-3 | 148.16 | 500 MG
Trans-Cinnamic acid is a natural antimicrobial that demonstrates a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1.
- Natural antimicrobial agent.
- Exhibits moderate inhibition against various fish pathogens.
- More effective on bacteria when the pH of the culture media is not neutralized.
- For research use only.
Medchemexpress LLC Tyrphostin AG30 | 122520-79-0 | MFCD09739079 | 99.7% | 205.17 | C10H7NO4 | 1 ML
Tyrphostin AG30 (CAS 122520-79-0) is a small-molecule inhibitor of EGFR tyrosine kinase supplied as a 10 mM solution in DMSO (1 mL), intended for biochemical and cell-based research.
- Potent and selective EGFR tyrosine kinase inhibition.
- Supplied as a ready-to-use 10 mM solution in DMSO.
- High purity suitable for research applications.
- Molecular weight 205.17 and formula C10H7NO4 provided for characterization.
- Storage recommendations provided to maintain compound stability.
Medchemexpress LLC Z-Entacapone | 145195-63-7 | 305.29 | 25 MG
(Z)-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor Entacapone. It is also a potential impurity found in commercial preparations of Entacapone and a degradant of Entacapone formed by UV light exposure.
- Metabolite of the catechol-O-methyltransferase (COMT) inhibitor Entacapone
- Potential impurity in commercial Entacapone preparations
- Degradant of Entacapone formed by UV light exposure
- Molecular formula: C14H15N3O5
- SMILES: O=C(N(CC)CC)/C(C#N)=C\C1=CC([N+]([O-])=O)=C(O)C(O)=C1
- Targets COMT
- Involves metabolic enzyme/protease and neuronal signaling pathways
Apexbio Technology LLC Tyrphostin 9 10537-47-0 25mg
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
Sigma Aldrich Fine Chemicals Biosciences trans-Cinnamic-d7 acid 98 atom % D | 308796-47-6 | MFCD01863723 | 500MG
trans-Cinnamic-d7 acid 98 atom % D | Mol Wt: 155.2 | 308796-47-6 | MFCD01863723 | 500MG
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 10 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor used as a research reagent to investigate EGFR signaling and related pathways. The compound is supplied as a light yellow to yellow solid with high reported purity and is offered in multiple solid sizes and DMSO solution formats.
- Inhibits EGFR kinase; reported IC50 ≈ 560 μM
- Also exhibits GTPase inhibitory activity
- High purity for reproducible experimental results
- Available as solid and as 10 mM DMSO solution in multiple sizes
- Storage recommended: solid at 4°C under nitrogen; solutions at -80°C or -20°C
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | 98.0% | 170.17 g/mol | C10H6N2O | 5 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor supplied for research use. It inhibits EGFR kinase (IC50 = 560 μM), acts as a GTPase inhibitor, and inhibits calcineurin (IC50 = 21 μM). The compound is provided as a high-purity solid and is available in small-mass vials or as a DMSO solution for in vitro biochemical and cell-based assays.
- High purity (>98%), suitable for in vitro studies.
- Known activity against EGFR, GTPase, and calcineurin targets.
- Molecular weight 170.17 g/mol and formula C10H6N2O.
- Available in multiple small pack sizes and as a 10 mM DMSO solution.
- Light yellow to yellow solid for handling and storage.
Medchemexpress LLC Lassbio-1135 | 852453-71-5 | 99.1% | C18H14N4 | 10MG
LASSBio-1135 is an orally active TRPV1 antagonist and anti-inflammatory/analgesic research compound. It shows moderate inhibition of human PGHS-2 (IC50 = 18.5 μM) and has demonstrated in vivo efficacy reversing capsaicin-induced thermal hyperalgesia and reducing carrageenan-induced paw edema. The material is supplied as a white to off-white solid with reported high purity and recommended low-temperature storage for stability.
- orally active TRPV1 antagonist with anti-inflammatory and analgesic activity
- moderate inhibition of human PGHS-2 (IC50 = 18.5 μM)
- demonstrated in vivo efficacy in pain and inflammation models
- high purity solid, white to off-white appearance
- recommended storage at low temperatures for long-term stability
eMolecules 4-Bromo-2-fluorocinnamic acid | 149947-19-3 | MFCD00143267 | 1g
Oakwood Chemical | 4-Bromo-2-fluorocinnamic acid | 1g | 537665361 | 004225 | | 149947-19-3 | MFCD00143267 | 245.047 | C9H6BrFO2
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Sigma Aldrich Fine Chemicals Biosciences SB-366791 >=98% (HPLC), powder | 472981-92-3 | MFCD01033818 | 5MG
SB-366791 >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 287.74 | 472981-92-3 | MFCD01033818 | 5MG