Cinnamic acids and derivatives
Apexbio Technology LLC Sodium ferulic 24276-84-4 100mg
Sodium ferulic (CAS 24276-84-4) is a small molecule inhibitor targeting fibroblast growth factor receptors specifically FGFR1 and FGFR2 It demonstrates inhibitory activity with IC50 values of 3 78 M for FGFR1 and 12 5 M for FGFR2 At the cellular level sodium ferulic suppresses intracellular signaling pathways involved in cell proliferation This compound is utilized in biomedical research to investigate signaling mechanisms and to assess therapeutic potential in disease models such as cancer
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 25mg
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
eMolecules 4'-(3-Fluorobenzyloxy)acetophenone | 93291-55-5 | MFCD06411642 | 5g
Oakwood Chemical | 4'-(3-Fluorobenzyloxy)acetophenone | 5g | 537680027 | 022128 | | 93291-55-5 | MFCD06411642 | 244.265 | C15H13FO2
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Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | 97.0% | 280.36 g/mol | C19H20O2 | 5 MG
(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one is a diarylheptanoid small-molecule for laboratory research and analytical applications. The compound is supplied as a solid with molecular formula C19H20O2, molecular weight 280.36 g/mol, and an analytical purity of 97.0% (NMR). Store protected from light at low temperatures; consult the certificate of analysis for batch-specific handling and stability information.
- Solid, white to off-white appearance.
- Molecular formula C19H20O2.
- Molecular weight 280.36 g/mol.
- Analytical purity 97.0% (NMR).
- Storage: keep container tightly sealed, protect from light; recommended -20°C for solid, in solvent -80°C for 6 months or -20°C for 1 month.
- Intended for research and analytical use only; not for human therapeutic use.
Chem-Impex International, Inc. trans-4-Bromocinnamic acid | MFCD00004394 | 5G
trans-4-Bromocinnamic acid, MFCD00004394, 5G
Matrix Scientific 4-(TRIFLUOROMETHYL)CINNAMI-25G
4-(Trifluoromethyl)cinnamic acid, 98%; 25g,C10H7F3O2, MFCD00002696, mw 216.16, [16642-92-5]
eMolecules 2'-(4-Fluorobenzyloxy)acetophenone | 400878-24-2 | MFCD03001269 | 1g
Oakwood Chemical | 2'-(4-Fluorobenzyloxy)acetophenone | 1g | 537671485 | 010106 | | 400878-24-2 | MFCD03001269 | 244.265 | C15H13FO2
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Medchemexpress LLC 4-chlorocinnamic acid | 1615-02-7 | MFCD00004396 | 100.0% | 182.61 g/mol | C9H7ClO2 | 25g
4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A) 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0 477 mM and 0 229 mM respectively 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4]
eMolecules 2-(Trifluoromethyl)cinnamicacid | 2062-25-1 | MFCD00004381 | 25g
Ambeed | 2-(Trifluoromethyl)cinnamicacid | 25g | 589771508 | A698959 | | 2062-25-1 | MFCD00004381 | 216.159 | C10H7F3O2
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Medchemexpress LLC M-carboxycinnamic acid bishydroxamide | 174664-65-4 | MFCD03453553 | 98.0% | 222.20 g·mol^-1 | C10H10N2O4 | 5 MG
m-Carboxycinnamic acid bishydroxamide (CBHA) is a small-molecule histone deacetylase (HDAC) inhibitor supplied for research use. It is used in biochemical and cellular assays to probe chromatin regulation, gene expression, and apoptosis pathways, with reported activity against HDAC1 and HDAC3.
- potent HDAC1 and HDAC3 inhibition (reported ID50 ≈ 10 nM and 70 nM)
- high purity suitable for biochemical assays (98.0%)
- available in small sample sizes for screening and method development
- stable as a powder when stored at low temperature
- compatible with in vitro cellular and enzymatic studies