Cinnamic acids and derivatives
Medchemexpress LLC Tyrphostin A1 | 2826-26-8 | 98.96% | 184.19 | 1 ML
Tyrphostin A1 | 2826-26-8 | 98.96% | 184.19 | 1 ML
Medchemexpress LLC Arn 077 enantiomer | 1439366-88-7 | 99.7% | 1 MG
Arn 077 enantiomer is the less active enantiomer of ARN 077 and functions as an inhibitor of N-acylethanolamine acid amidase (NAAA); reported IC50 for rat NAAA is 3.53 μM. Supplied as a solid for research applications.
- Less active enantiomer with reported IC50 = 3.53 μM for rat NAAA.
- Chemical formula C16H21NO4; molecular weight 291.34 g/mol.
- White to off-white solid; powder storage at -20°C for long-term stability.
- High DMSO solubility (100 mg/mL); vehicle formulations reported for in vivo use at ≥ 2.5 mg/mL.
- For research use only; handle according to appropriate safety procedures.
Selleck Chemical LLC (R)-(-)-JQ1 Enantiomer S2965-5mg
(R)-(-)-JQ1 Enantiomer is the stereoisomer of ( )-JQ1 ( )-JQ1 potently decreases expression of both BRD4 target genes whereas (R)-(-)-JQ1 Enantiomer has no effect
Medchemexpress LLC Trans,trans-2,4-hexadien-1-ol | 17102-64-6 | MFCD00002925 | >=97.0% | 98.14 g/mol | C6H10O | 5 G
(2E,4E)-Hexa-2,4-dien-1-ol (trans,trans-2,4-hexadien-1-ol) is a small unsaturated aliphatic alcohol used as a research reagent and synthetic intermediate. It is commonly supplied stabilized to reduce oxidation and is employed in organic synthesis and analytical applications. Key identifiers include CAS 17102-64-6 and formula C6H10O.
- Unsaturated aliphatic alcohol for organic synthesis and research
- Typically supplied stabilized to limit oxidation
- Typical purity ≥97.0%
- Chemical formula C6H10O; molecular weight 98.14 g/mol
- Suitable for small-scale laboratory and analytical use
Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | 97.0% | 280.36 g/mol | C19H20O2 | 5 MG
(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one is a diarylheptanoid small-molecule for laboratory research and analytical applications. The compound is supplied as a solid with molecular formula C19H20O2, molecular weight 280.36 g/mol, and an analytical purity of 97.0% (NMR). Store protected from light at low temperatures; consult the certificate of analysis for batch-specific handling and stability information.
- Solid, white to off-white appearance.
- Molecular formula C19H20O2.
- Molecular weight 280.36 g/mol.
- Analytical purity 97.0% (NMR).
- Storage: keep container tightly sealed, protect from light; recommended -20°C for solid, in solvent -80°C for 6 months or -20°C for 1 month.
- Intended for research and analytical use only; not for human therapeutic use.
Medchemexpress LLC Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide | 866602-52-0 | 98.5% | 247.38 | C16H25NO | 5mg
Dodeca-2E 4E 8Z 10Z/E-N-tetraenoic acid isobutylamide is a brain-penetrant substance and the main alkamide in Echinacea preparations which might be used for research of common cold and various upper respiratory infections[1]
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MM 1ML
SAR405 R enantiomer is the less active enantiomer of SAR405, a selective inhibitor of PIK3C3/Vps34, supplied for research use. It is offered as a ready-to-use 10 mM solution in DMSO or as a solid, and is used as a reference or control in studies of autophagy, vesicle trafficking, and related signaling pathways.
- Less active enantiomer of a PIK3C3/Vps34 inhibitor.
- High purity (~99.9%) for reliable experimental controls.
- Available as 10 mM solution in DMSO and multiple solid package sizes.
- Soluble in DMSO at 100 mg/mL; ultrasonication may be required.
- Storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
- Intended for research use only, not for clinical applications.
TARGETMOL CHEMICALS INC CIPROPRIDE S ENANTIOMER 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cipropride S enantiomer is the S enantiomer of cipropride which is an antiemetic drug. purity: 99%
Selleck Chemical LLC Tyrphostin AG 879 S2816-25mg
Tyrphostin AG 879 potently inhibits HER2/ErbB2 with IC50 of 1 M 100- and 500-fold higher selective to ErbB2 than PDGFR and EGFR
TARGETMOL CHEMICALS INC DUVELISIB R ENANTIOMER H 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib.
Medchemexpress LLC 1,6-heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)- | 458-37-7 | MFCD00008365 | 97.3% | 368.38 g·mol^-1 | C21H20O6 | 10 MG
Curcumin (diferuloylmethane) is a natural phenolic research reagent that functions as a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase. It modulates NF-κB and MAPK pathways, stabilizes Nrf2 through Keap1 cysteine modification, and exhibits anti-inflammatory, antioxidant, antiproliferative, and antiangiogenic activities. Supplied as a characterized powder with recommended storage conditions and a COA.
Apexbio Technology LLC Curcumin(Synonyms: Diferuloylmethane, Turmeric yellow, Natural yellow 3, CI 75300), 100mg, CAS: 458-37-7.
Curcumin (CAS 458-37-7) is a natural small molecule known to inhibit tyrosinase activity with an IC50 of 47 M It modulates multiple signaling pathways involved in tumorigenesis and inflammation influencing transcription factors growth factors cytokines receptors and enzymes Clinical trials at Phase I reported no observed toxicity at doses up to 12 g/day however oral bioavailability is limited ( 1% in Phase I/II studies) Additionally curcumin demonstrates potential for Alzheimer s research as evidenced by reducing beta-amyloid (A 40 A 42) production via downregulating presenilin-1 and GSK-3 in SH-SY5Y neuroblastoma cells
Cayman Chemical Plnt TurmerIc CurcumIn 50g
A yellow pigment with diverse biological activities; inhibits NO production (IC50 = 6 μM) and reduces iNOS activity in LPS-stimulated RAW 264.7 cells; inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells; decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis; prevents ovalbumin-induced accumulation of 3-NT in mouse heart; reduces TPA-induced tumor formation in mouse skin (1-10 μmol); reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-NQO in rats
Sigma Aldrich Fine Chemicals Biosciences Curcumin from Curcuma longa (Turmeric), powder | 458-37-7 | MFCD00008365 | 5G
Curcumin from Curcuma longa (Turmeric), powder | Purity: >=65% (HPLC) | Mol Wt: 368.38 | 458-37-7 | MFCD00008365 | 5G
