Cinnamic acids and derivatives
![Medchemexpress LLC 2-Propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 g/mol | C18H19NO3 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000209428.png-250.jpg)
Medchemexpress LLC 2-Propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 g/mol | C18H19NO3 | 1 G
Aegeline is an alkaloid reference standard intended for research use that mimics the yeast SNARE protein Sec22p and suppresses α-synuclein and Bax toxicity in yeast while exhibiting antioxidant activity.
- Alkaloid reference standard for research use.
- Cas number: 456-12-2.
- Chemical formula: C18H19NO3; molecular weight: 297.35 g/mol.
- Purity 99.81% (as provided on the certificate of analysis).
- Form: white to off-white solid powder.
- Solubility: soluble in DMSO (100 mg/mL); in vivo formulations listed for dosing preparations.
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solution at -80°C or -20°C for shorter periods.
- Pack size: 1 g.
Medchemexpress LLC 3,4-Dimethoxycinnamic acid | 2316-26-9 | 208.21 | 5 G
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. It exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effects.
- Extracted and purified from Securidaca inappendiculata Hassk.
- Exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway.
- Anti-apoptotic effects.
Medchemexpress LLC Ferulic acid acyl-β-D-glucoside | 7196-71-6 | 10 MG
Ferulic acid acyl-β-D-glucoside is a metabolite of ferulic acid. It can be isolated from flaxseed extract. Ferulic acid is identified as a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor.
- Metabolite of ferulic acid.
- Can be isolated from flaxseed extract.
- Acts as a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50 values of 3.78 and 12.5 μM for FGFR1 and FGFR2.
- Purity: 99.33%.
Medchemexpress LLC Tyrphostin AG1296 | 146535-11-7 | 99.7% | 266.29 | 25 MG
Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), with an IC50 of 0.8 μM. It inhibits signaling of human PDGF α- and β-receptors, as well as the related stem cell factor receptor (c-Kit). This compound is also a potent inhibitor of FLT3, with an IC50 in the micromolar range.
- Potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR)
- Inhibits signaling of human PDGF α- and β-receptors
- Inhibits signaling of the related stem cell factor receptor (c-Kit)
- Potent inhibitor of FLT3
- Suppresses viability of PLX4032-resistant melanoma cells
- Induces apoptosis of A375R cells
- Inhibits PDGFR phosphorylation
- Suppresses A375R tumor growth in vivo
- Inhibits atherosclerotic plaque progression
Sigma Aldrich Fine Chemicals Biosciences p-Coumaric acid primary reference standard | 501-98-4 | MFCD00004399 | 50MG
p-Coumaric acid primary reference standard | Mol Wt: 164.16 | 501-98-4 | MFCD00004399 | 50MG
Medchemexpress LLC 3,4-Dimethoxycinnamic acid (O-methylferulic acid) | 2316-26-9 | 208.21 | 1 ML
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. It exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway.
- Monomer extracted and purified from securidaca inappendiculata hassk.
- Exerts anti-apoptotic effects on L-02 cells.
- Acts via the ROS-mediated signaling pathway.
- Attenuates ethanol-induced apoptosis in L-02 cells.
- Inhibits expression levels of Nox4 and p22phox.
- Decreases expression levels of superoxide dismutase, catalase, and phospholipid hydroperoxide gluthione peroxidase.
- Downregulates Bax/Bcl-2 and cleaved forms of caspase-3.
- For research use only.
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 1 ML
4-Methoxycinnamic acid | 830-09-1 | 178.19 | 1 ML
Medchemexpress LLC 2-Methoxycinnamic acid | 6099-03-2 | 178.18 | 500 G
2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase. It is intended for research use only.
- Purity: 99.94%
- CAS number: 6099-03-2
- Molecular weight: 178.18
- Formula: C10H10O3
- Appearance: Solid
- Color: White to off-white
- SMILES: O=C(O)/C=C/C1=CC=CC=C1OC
- Structure classification: Phenylpropanoids, Simple Phenylpropanols
- Initial source: Plants, Ranunculaceae, Pulsatilla chinensis (Bunge) Regel
- Shipping: Room temperature in continental US
- Storage: Powder at -20°C for 3 years, 4°C for 2 years; In solvent at -80°C for 2 years, -20°C for 1 year
Medchemexpress LLC Ozagrel hydrochloride | 78712-43-3 | MFCD06795644 | >98.0% | 10 MG
Ozagrel hydrochloride is the hydrochloride salt of ozagrel, a selective thromboxane A2 (TXA2) synthase inhibitor used in preclinical research to study platelet aggregation, ischemic stroke, asthma, and thromboembolic disease.
- Selective thromboxane A2 (TXA2) synthase inhibitor with reported IC50 ~11 nM.
- Reduces thromboxane A2 production, leading to anti-platelet aggregation and vasodilation.
- Hydrochloride salt supplied as a powder suitable for in vitro and in vivo research.
- Typical molecular weight 264.71 g/mol and formula C13H13ClN2O2.
- High purity commonly reported as ≥98% (verify with vendor for specific lot).
- Store powder at -20°C for long-term stability; in solution, store at -80°C.