Cinnamic acids and derivatives
Medchemexpress LLC 2-Propenoic acid,3-(3-hydroxyphenyl)- | 588-30-7 | 100.0% | 164.16 | 100 MG
m-Coumaric acid is a polyphenol metabolite derived from caffeic acid, produced by gut microflora, and its concentration in human biofluids depends on diet. It is a BBB-penetrant metabolite of chlorogenic acid. In vitro, m-Coumaric acid stimulates cerebral nerves and can evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation.
- Increases spontaneous locomotor activity in mice
- Inhibits L-dopa oxidation by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Suitable for research and analytical applications
Medchemexpress LLC M-coumaric acid | 588-30-7 | 99.8% | 164.16 | 1 ML
m-Coumaric acid is an endogenous metabolite and polyphenol that is formed from caffeic acid by gut microflora. It is a BBB-penetrant metabolite of chlorogenic acid and can stimulate cerebral nerves and evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation. It has also been shown to increase spontaneous locomotor activity in mice.
- Inhibits the oxidation of L-dopa by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Stimulates cerebral nerves in vitro
- Promotes neuronal differentiation
- Increases spontaneous locomotor activity
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.91% | 164.16 | 25 MG
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid, intended for research and analytical applications. It is a polyphenol metabolite from caffeic acid, formed by gut microflora, with its amount in human biofluids being diet-dependent. m-Coumaric acid is also a BBB-penetrant metabolite of chlorogenic acid.
- Stimulates the cerebral nerves in vitro.
- Can evoke neurite outgrowth in hippocampal neuronal cells.
- Can promote neuronal differentiation.
- Increases spontaneous locomotor activity in mice by acting on the central nervous system.
- Inhibits the oxidation of L-dopa by epidermis tyrosinase.
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats.
Medchemexpress LLC (E)-Ferulic acid | 537-98-4 | 99.9% | 194.19 | 1 ML
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound found in plant cell walls. It causes phosphorylation of β-catenin, leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax, and reducing the expression of the survival factor survivin. It can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation, and exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.
- Removes reactive oxygen species (ROS)
- Inhibits lipid peroxidation
- Exerts antiproliferative effects in human lung cancer cells
- Exerts antimigratory effects in human lung cancer cells
- Induces phosphorylation and proteasome degradation of β-catenin
- Increases expression of pro-apoptotic factor Bax
- Reduces expression of the survival factor survivin
- Reduces liver and kidney toxicity and oxidative stress
Medchemexpress LLC Trans-cinnamic acid (standard) | 140-10-3 | 148.16 | 50 MG
trans-Cinnamic acid (Standard) serves as an analytical standard for research and analytical applications. It acts as a natural antimicrobial and is suitable for various laboratory experiments including HPLC, GC, and MS, as a reference standard assay.
- Analytical standard for trans-Cinnamic acid.
- Intended for research and analytical applications.
- Natural antimicrobial with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1.
- Used as a reference standard assay.
- Utilized in qualitative, quantitative, and methodological research experiments.
- Compatible with techniques such as HPLC, GC, and MS.
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | 98.71% | 164.16 | 25 MG
2-Hydroxycinnamic acid (Standard) is the analytical standard of 2-Hydroxycinnamic acid, intended for research and analytical applications. It is a phenolic acid with antimicrobial and antioxidant properties.
- Antimicrobial activity against Staphylococcus aureus, not susceptible to drug resistance.
- Shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM.
- Has neuroprotective and antitumor activity.
- The compound is an analytical standard, commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
TARGETMOL CHEMICALS INC trans-Cinnamic acid 1G
Also available in 1 mL, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. trans-Cinnamic acid (Myricitrine) exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro. Purity 99.96%