Coumarins and derivatives
Indofine Chemical MYRICETIN, Flavonoid & Coumarins, 529-44-2, 0.98, 50 mg
MYRICETIN, Flavonoid & Coumarins, 529-44-2, 0.98, 50 mg
Cayman Chemical 3-HydroxycoumarIn 1g
A coumarin with diverse biological activities; inhibits 15-LO-1 (IC50 = 9.5 µM); scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM); inhibits lipid peroxidation in vitro (IC50 = 69.07 mM); protective against UVB-induced embryotoxicity in sea urchins
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 50 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase (LOX), with an IC50 for recombinant human tyrosinase (rHT) of 26 μM and an IC50 for LOX of 9.5 μM. It exhibits DPPH free radical scavenging activity and has photoprotective effects on sea urchin zygotes and embryos. The compound has also demonstrated anticancer activity against human SK-MEL-28 cells and SK-MEL3 cells in vitro.
- Inhibits tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Provides photoprotective effects on sea urchin zygotes and embryos
- Shows anticancer activity against human SK-MEL-28 and SK-MEL3 cells
- Can be formulated into a vesicle delivery system for topical administration
Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | MFCD00037568 | ≥95.0% | 5 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye for labeling proteins and nucleic acids.
- Fluorescent dye
- Amine-reactive succinimidyl ester
- Labels proteins and nucleic acids
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 10 G
6-Hydroxycoumarin is a coumarin exhibiting diverse biological activities. It is noted for its anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator properties. This compound also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor activities.
- Demonstrates anti-inflammatory, anti-pyretic, and anti-oxidant activities
- Acts as a vasodilator, anti-amoebic, anti-bacterial, and anti-fungal agent
- Exhibits bacteriostatic and antitumor properties
- Appearance: light yellow to light brown solid
- Molecular formula: C9H6O3
- Molecular weight: 162.14
- Purity: 99.32%
- Melting point: 249-253 °C
- Boiling point: 248.82 °C at 760 mmHg
Medchemexpress LLC (2,5-dioxopyrrolidin-1-yl) 7-hydroxy-2-oxochromene-3-carboxylate | 134471-24-2 | MFCD00037568 | >96.0% | 303.22 g/mol | C14H9NO7 | 10 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is an N-hydroxysuccinimide (NHS)-activated fluorescent labeling reagent that introduces a 7-hydroxycoumarin fluorophore onto primary amines. Provided as a solid for research use, it is intended for bioconjugation and fluorescence-based assays.
- Reacts with primary amines via NHS ester chemistry for covalent labeling.
- Provides a blue/UV-excitable coumarin fluorophore suitable for protein, peptide, and nucleic acid labeling.
- Available in small-scale quantities convenient for analytical and preparative labeling.
- High chemical purity suitable for coupling reactions (suppliers report >96%).
- Stable when stored as directed; consult the product datasheet or certificate of analysis for storage and handling details.
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 250 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase, with an IC50 of 26 μM for recombinant human tyrosinase (rHT) and a Ki of 3.39 μM. It also demonstrates DPPH free radical scavenging activity (IC50 = 31.2 μM) and has photoprotective effects on sea urchin zygotes and embryos. This compound can be developed into a vesicle delivery system for local administration to achieve efficient local accumulation in the skin, facilitating the study of diseases related to excessive skin pigmentation.
- Acts as an inhibitor of tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Offers photoprotective effects on sea urchin zygotes and embryos
- Can be formulated into a vesicle delivery system for topical applications
- Effective in inhibiting the first cleavage of sea urchin embryos in a concentration-dependent manner