Coumarins and derivatives
Medchemexpress LLC My-1076 | 3008262-76-5 | MFCD35444266 | 99.1% | 539.57 g·mol-1 | C29H33NO9 | 10 MG
MY-1076 is a small-molecule inhibitor of Yes-associated protein (YAP) used for laboratory research. It induces YAP degradation and apoptosis and shows potent antiproliferative activity against several cancer cell lines with low-nanomolar IC50s. Reported properties include CAS 3008262-76-5, formula C29H33NO9, molecular weight 539.57 g·mol-1, and high reported purity.
- Induces YAP degradation and apoptosis in vitro
- Potent antiproliferative activity with low-nanomolar IC50s
- High purity suitable for analytical and biological studies
- Available in multiple small-scale quantities for research use
- Intended for research use only; not for human or clinical use
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES 7-METHOXYCOUMARIN-4-ACETYL-GL
NC3736128 7-METHOXYCOUMARIN-4-ACETYL-GL
Sigma Aldrich Fine Chemicals Biosciences Esculin hydrate >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 50G
Esculin hydrate >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 50G
Research Products International Corp Esculin, 500 G
- CAS Number: 531-75-9
- Molecular Formula: C15H16O9 • xH2O
- Molecualr Weight: 340.28 g/mol
Medchemexpress LLC Coumarin-6-sulfonyl chloride | 10543-42-7 | 95.0% | 100 MG
Coumarin-6-sulfonyl chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Used as a biological material
- Used as an organic compound for life science related research
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 50 G
4-Hydroxycoumarin is an orally active coumarin derivative, a versatile heterocyclic scaffold used in synthesizing various organic compounds. It possesses both electrophilic and nucleophilic properties. It acts as an HIV protease inhibitor and tyrosine kinase inhibitor, and exhibits anti-inflammatory, antibacterial, and anti-tumor effects.
- Orally active coumarin derivative
- Versatile heterocyclic scaffold for organic compound synthesis
- Possesses both electrophilic and nucleophilic properties
- Acts as an HIV protease inhibitor
- Acts as a tyrosine kinase inhibitor
- Exhibits anti-inflammatory effects
- Exhibits antibacterial effects
- Exhibits anti-tumor effects
Sigma Aldrich Fine Chemicals Biosciences 7-Ethoxycoumarin | 31005-02-4 | MFCD00006877 | 25mg
7-Ethoxycoumarin | Purity: 99% | Mol Wt: 190.2 | 31005-02-4 | MFCD00006877 | 25mg
Bachem Fmoc-b-(7-methoxy-coumarin-4-yl)-Ala-OH
Fmoc-b-(7-methoxy-coumarin-4-yl)-Ala-OH, 524698-40-6, C28H23NO7, Mr 485.49, 500mg. (S)-2-(Fmoc-amino)-3-(7-methoxy-2-oxo-2H-chromen-4-yl)-propionic acid, Fmoc-b-(O-methyl-umbellifer-4-yl)-Ala-OH. Fmoc-protected coumarinyl alanine derivative useful for the incorporation of a fluorescent label into a peptide sequence during solid (SPPS) or solution phase peptide synthesis.
Sigma Aldrich Fine Chemicals Biosciences 4-Methylumbelliferyl phosphate disodium salt | 22919-26-2 | MFCD00037614 | 250 mg
4-Methylumbelliferyl phosphate disodium salt | Mol Wt: 300.11 | 22919-26-2 | MFCD00037614 | 250 mg
Chem-Impex International, Inc. 3-Cyanocoumarin | MFCD00115699 | 25G
3-Cyanocoumarin, MFCD00115699, 25G
Medchemexpress LLC 7-hydrazinyl-4-methyl-2H-chromen-2-one | 113707-87-2 | MFCD09999551 | 97.1% | 190.20 | C10H10N2O2 | 100MG
Coumarin hydrazine is a fluorescent chemical probe used to label protein- and lipid-bound carbonyls in cells and biochemical assays. It reacts with aldehydes and ketones to form fluorescent hydrazones, producing a measurable signal suitable for live-cell and in vitro labeling when handled protected from light (λex = 420-450 nm; λem ≈ 468 nm).
- Fluorogenic probe for labeling protein- and lipid-bound carbonyls.
- Reacts with aldehydes and ketones to form fluorescent hydrazones.
- Excitation 420-450 nm; emission ≈468 nm.
- Molecular formula C10H10N2O2; molecular weight 190.20.
- Purity 97.1%; supplied as a 100 mg solid.
- Protect from light; in solvent store at -80°C for up to 6 months or at -20°C for up to 1 month.
Apexbio Technology LLC Psoralen,20mgCAS# 66-97-7
Psoralen is used as photochemical probe in studies of DNA mutation and repair mechanisms. Causes photosensitization in human. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC HX 531 188844-34-0 25mg
HX 531 (CAS 188844-34-0) is a small-molecule antagonist targeting the retinoid X receptor (RXR) It modulates RXR-associated signaling pathways thereby influencing both tumorigenic and metabolic biological processes HX 531 exerts its biological activity by antagonizing RXR which results in cell cycle arrest at the G0/G1 phase and modulation of leptin-dependent pathways and the p53-p21Cip1 signaling axis In rodent models HX 531 demonstrates an inhibitory activity with an IC50 value of approximately 18 nM Based on these pharmacological properties HX 531 holds research potential in the study of metabolic disorders obesity diabetes and cancer biology