Coumarins and derivatives
Medchemexpress LLC My-1076 | 3008262-76-5 | MFCD35444266 | 99.1% | 539.57 g·mol-1 | C29H33NO9 | 10 MG
MY-1076 is a small-molecule inhibitor of Yes-associated protein (YAP) used for laboratory research. It induces YAP degradation and apoptosis and shows potent antiproliferative activity against several cancer cell lines with low-nanomolar IC50s. Reported properties include CAS 3008262-76-5, formula C29H33NO9, molecular weight 539.57 g·mol-1, and high reported purity.
- Induces YAP degradation and apoptosis in vitro
- Potent antiproliferative activity with low-nanomolar IC50s
- High purity suitable for analytical and biological studies
- Available in multiple small-scale quantities for research use
- Intended for research use only; not for human or clinical use
Cayman Chemical 4-HydroxycoumarIn 500g
A coumarin; inhibits vitamin K1 epoxidation and prothrombin synthesis by 18 and 67%, respectively, in cell-free assays at 6.2 mM; has been used in the synthesis of anticoagulants, as well as antithrombotic, anti-inflammatory, antibacterial, and antifungal agents
Cayman Chemical 3-HydroxycoumarIn 5g
A coumarin with diverse biological activities; inhibits 15-LO-1 (IC50 = 9.5 µM); scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM); inhibits lipid peroxidation in vitro (IC50 = 69.07 mM); protective against UVB-induced embryotoxicity in sea urchins
Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | MFCD00037568 | ≥95.0% | 5 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye for labeling proteins and nucleic acids.
- Fluorescent dye
- Amine-reactive succinimidyl ester
- Labels proteins and nucleic acids
Chem-Impex International, Inc. 7-Hydroxy-4-methylcoumarin | 90-33-5 | MFCD00006866 | 25G
7-Hydroxy-4-methylcoumarin, 90-33-5, MFCD00006866, 25G
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
Medchemexpress LLC 7-Hydroxycoumarin-4-acetic acid | 6950-82-9 | 250 MG
7-Hydroxycoumarin-4-acetic acid is a pH-indicator dye that is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). This product is intended for research use only.
- pH-indicator dye
- Covalently bound to bovine serum albumin (BSA)
- White to off-white solid
- Molecular weight 220.18
- Chemical formula C11H8O5
- Emission (Em): 450
- Excitation (Ex): 415
- Store at 4°C, protect from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 50MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 50MG
Medchemexpress LLC 7-Ethoxy-4-methylcoumarin | 87-05-8 | 99.44% | 50 G
7-Ethoxy-4-methylcoumarin is a coumarin derivative that functions as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6.
- Coumarin derivative
- Substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6
- Molecular weight: 204.22
- Formula: C12H12O3
- Appearance: Solid
- Color: White to off-white
- SMILES: O=C1C=C(C)C2=CC=C(OCC)C=C2O1
Medchemexpress LLC Daphnetin (7,8-dihydroxycoumarin) | 486-35-1 | 99.8% | 178.14 | 5 MG
Daphnetin (7,8-dihydroxycoumarin) is a coumarin derivative found in plants of the Genus Daphne. It is a potent, orally active protein kinase inhibitor.
- Has IC50s of 7.67 μM, 9.33 μM, and 25.01 μM for EGFR, PKA, and PKC in vitro, respectively.
- Triggers ROS-induced cell apoptosis.
- Induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway.
- Possesses anti-inflammatory activity, inhibiting TNF-α, IL-1β, ROS, and MDA production.
- Exhibits schizontocidal activity against malaria parasites.
- Can be utilized in research for rheumatoid arthritis, cancer, and anti-malarial purposes.
Indofine Chemical Linarin With Hplc, 5 Mg
LINARIN with HPLC, Flavonoid & Coumarins, 480-36-4, 98.5% by HPLC, 5 mg