Coumarins and derivatives
Apexbio Technology LLC 3-Nitrocoumarin 28448-04-6 5mg
3-Nitrocoumarin (CAS 28448-04-6) is a selective inhibitor of phospholipase C- (PLC- ) an enzyme involved in cellular signal transduction through the hydrolysis of membrane phospholipids and subsequent generation of secondary messengers By suppressing PLC- catalytic activity 3-Nitrocoumarin disrupts related intracellular signaling pathways thereby enabling investigation of PLC- -mediated mechanisms in various physiological and pathological contexts This compound is widely utilized in studies focused on elucidating the roles of PLC- in disease models and fundamental biomedical research
Apexbio Technology LLC 3-Nitrocoumarin 28448-04-6 10mg
3-Nitrocoumarin (CAS 28448-04-6) is a selective inhibitor of phospholipase C- (PLC- ) an enzyme involved in cellular signal transduction through the hydrolysis of membrane phospholipids and subsequent generation of secondary messengers By suppressing PLC- catalytic activity 3-Nitrocoumarin disrupts related intracellular signaling pathways thereby enabling investigation of PLC- -mediated mechanisms in various physiological and pathological contexts This compound is widely utilized in studies focused on elucidating the roles of PLC- in disease models and fundamental biomedical research
Medchemexpress LLC 3-Nitrocoumarin | 28448-04-6 | 100.0% | 191.14 | 50 MG
3-Nitrocoumarin is an inhibitor for phospholipase C that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway.
- Purity of 100.0%
- CAS number 28448-04-6
- Molecular weight of 191.14
- Molecular formula C9H5NO4
- Appears as a solid
- Color is light yellow to yellow
- Targets phospholipase and fungal pathways
- Affects metabolic enzyme/protease and anti-infection pathways
- Inhibits glucose-induced increase of intracellular calcium ions in yeast strain WPY260
- Inhibits PLC in Neurospora crassa with an IC50 of 10 μg/mL
- Inhibits the growth of N. crassa and causes morphological changes of apical hyperbranching in hyphae
- Soluble in DMSO at ≥ 100 mg/mL
Medchemexpress LLC 3-Nitrocoumarin | 28448-04-6 | 100.0% | 191.14 | 1 ML
3-Nitrocoumarin is an inhibitor for phospholipase C that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway. This compound causes morphological changes of apical hyperbranching in *N. crassa* hyphae.
- Inhibits phospholipase C, affecting the calcium signaling pathway.
- Inhibits glucose-induced increase of intracellular calcium ions in yeast strain WPY260 (at 50 mg/mL for 6 min).
- Inhibits PLC in *Neurospora crassa* with an IC50 of 10 μg/mL.
- Inhibits the growth of *N. crassa* and causes morphological changes of apical hyperbranching in hyphae.
Medchemexpress LLC HY-111919 10mg Medchemexpress, 3-Nitrocoumarin CAS:28448-04-6 Purity:>98%
Medchemexpress, HY-111919 10mg 3-Nitrocoumarin CAS:28448-04-6 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 3-nitro-2H-1-benzopyran-2-one | 28448-04-6 | 100.0% | 191.14 | 100 MG
3-Nitrocoumarin is an inhibitor for phospholipase C (PLC) that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway. It is intended for research use only.
- Inhibits phospholipase C.
- Blocks the generation of inositol triphosphate (IP3).
- Affects the calcium signaling pathway.
- Inhibits glucose-induced increase of intracellular calcium ions in yeast strain WPY260.
- Inhibits PLC in Neurospora crassa with an IC50 of 10 μg/mL.
- Inhibits the growth of N. crassa and causes morphological changes of apical hyperbranching in hyphae.
eMolecules Medchem Express / 3-Nitrocoumarin / 5mg / 485251314 / HY-111919 / / 28448-04-6 / MFCD00233577 / 191.142 / C9H5NO4
Medchem Express / 3-Nitrocoumarin / 5mg / 485251314 / HY-111919 / / 28448-04-6 / MFCD00233577 / 191.142 / C9H5NO4