Isoflavonoids
Medchemexpress LLC Genistin | 529-59-9 | 432.38 | 100 MG
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of the ERalpha signaling pathway.
- An isoflavone belonging to the phytoestrogen family.
- Potent anti-adipogenic and anti-lipogenic agent.
- Attenuates cellular growth.
- Promotes apoptotic cell death in breast cancer cells through modulation of the ERalpha signaling pathway.
Medchemexpress LLC 5-Methyl-7-methoxyisoflavone | 82517-12-2 | 266.29 | 25 MG
5-Methyl-7-methoxyisoflavone is an orally active antioxidant with remyelinating activity. It inhibits the enzyme aromatase, interfering with the normal metabolic pathways of testosterone. It is a non-steroidal anabolic isoflavone used as an anabolic agent, showing better potency in increasing muscle mass and endurance. This compound can also be used for fat loss, maintaining low cholesterol levels, and strengthening bones. Additionally, 5-Methyl-7-methoxyisoflavone acts as an inhibitor for NF-κB.
- Orally active antioxidant with remyelinating activity.
- Inhibits aromatase enzyme.
- Non-steroidal anabolic isoflavone, acts as an anabolic agent.
- Increases muscle mass and endurance.
- Aids in fat loss.
- Helps maintain low cholesterol levels.
- Strengthens bones.
- Inhibitor for NF-κB.
- Inhibits the clonogenicity of HCT116 colon cancer cells in vitro.
Medchemexpress LLC Puerarin | 3681-99-0 | 98.9% | 416.38 | 1 ML
Puerarin is an isoflavone extracted from Pueraria root, functioning as a 5-HT2C receptor antagonist. It inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which leads to decreased fat absorption.
- Acts as a 5-HT2C receptor antagonist
- Inhibits LPS-induced iNOS, COX-2, and CRP protein and mRNA expression
- Functions as a novel open-channel blocker of IK1
- Alleviates hepatic damage from chronic alcohol administration
- Improves early-stage renal damage in diabetic rats
![Alkali Scientific Genistein [4',5,7 Trihydroxyisoflavone], 25 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661372.jpg-250.jpg)
Alkali Scientific Genistein [4',5,7 Trihydroxyisoflavone], 25 Mg
Genistein (4',5,7 Trihydroxyisoflavone), provided in a 25mg quantity, is an isoflavone commonly used as a kinase inhibitor in molecular biology and pharmacological research. It has a wide range of biological activities, particularly in inhibiting tyrosine kinases involved in signal transduction pathways. Genistein is used in cancer research, where it helps block signaling pathways that contribute to tumor growth and metastasis. It also has potential therapeutic applications in conditions such as osteoporosis, cardiovascular diseases, and inflammation. In laboratory studies, Genistein is used to explore the effects of kinase inhibition on cellular processes, gene expression, and cell survival.
Cayman Chemical Daidzein Fatty Acids and Deriv
An isoflavone; binds to ERβ (Ki = 2.8 µM) but not ERα up to 1 mM; estrogenic in vitro, increasing ERE-mediated gene transcription via ERβ (EC50 = 2.8 µM); an inhibitor of CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) and selective for them over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively); reduces tumor growth in a PC3 prostate cancer mouse orthtopic model at 50 mg/kg per day
Cayman Chemical Genistein Fatty Acids and Deri
An isoflavonoid phytoestrogen with kinase inhibitory, anticancer, pro-cancer, hepatoprotective, and antiviral properties; inhibits EGFR, pp50v-Src, and pp110gag-fes (IC50s = 6, 7-8, and 6.5 UG/ml, respectively); reduces tumor invasion and angiogenesis in a Bel 7402 mouse subrenal capsule xenograft model at 50 mg/kg per day; increases the incidence of uterine adenocarcinoma in a mouse model of cancer induced by DES at 50 mg/kg per day administered on postnatal days 1-5; reduces lipid accumulation and inflammation in the liver of OVX and non-OVX female rats in a model of high-fat high-fructose diet-induced model of NASH at 16 mg/kg per day; inhibits HIV-1 DNA synthesis in resting CD4+ T cells at 10 µM
Cayman Chemical Genistein Fatty Acids and Deri
An isoflavonoid phytoestrogen with kinase inhibitory, anticancer, pro-cancer, hepatoprotective, and antiviral properties; inhibits EGFR, pp50v-Src, and pp110gag-fes (IC50s = 6, 7-8, and 6.5 UG/ml, respectively); reduces tumor invasion and angiogenesis in a Bel 7402 mouse subrenal capsule xenograft model at 50 mg/kg per day; increases the incidence of uterine adenocarcinoma in a mouse model of cancer induced by DES at 50 mg/kg per day administered on postnatal days 1-5; reduces lipid accumulation and inflammation in the liver of OVX and non-OVX female rats in a model of high-fat high-fructose diet-induced model of NASH at 16 mg/kg per day; inhibits HIV-1 DNA synthesis in resting CD4+ T cells at 10 µM
Cayman Chemical Formononetin 25mg
An isoflavonoid phytoestrogenic compound found in soy-based foods; acts as an agonist of the aryl hydrocarbon receptor (EC50 = 0.13 µM) and has been reported to possess antitumor and antiviral activity
Cayman Chemical Daidzein Fatty Acids and Deriv
An isoflavone; binds to ERβ (Ki = 2.8 µM) but not ERα up to 1 mM; estrogenic in vitro, increasing ERE-mediated gene transcription via ERβ (EC50 = 2.8 µM); an inhibitor of CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) and selective for them over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively); reduces tumor growth in a PC3 prostate cancer mouse orthtopic model at 50 mg/kg per day
Sigma Aldrich Fine Chemicals Biosciences Genistein synthtic 98 HPL100MG
Genistein is an isoflavonoid present among Leguminosae family of plants. It is structurally similar to estrogen (estradiol-17).
