Linear 1 3-diarylpropanoids
Medchemexpress LLC 4-hydroxychalcone | 20426-12-4 | MFCD00016488 | 99.3% | 224.25 g/mol | C15H12O2 | 1 ML
4-Hydroxychalcone is a chalcone metabolite supplied as a 10 mM solution in DMSO for research use. It is reported to inhibit TNF-α-induced NF-κB activation and to exhibit anti-angiogenic and anti-inflammatory effects, providing a high-purity, ready-to-use stock for cell-based and biochemical assays. Handle under recommended storage conditions and protect from light.
- 10 mM solution in DMSO.
- High purity: 99.3%.
- Molecular formula C15H12O2; molecular weight 224.25 g/mol.
- CAS number 20426-12-4.
- Inhibits TNF-α-induced NF-κB pathway; anti-angiogenic and anti-inflammatory activity.
- Store protected from light; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Selleck Chemical LLC Chalcone
Chalcone (benzylideneacetophenone phenyl styryl ketone benzalacetophenone -phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds which are known collectively as chalcones with antibacterial antifungal antitumor and anti-inflammatory properties
Medchemexpress LLC Chalcone | 94-41-7 | 100.0% | 50 MG
Chalcone is the parent α,β-unsaturated ketone scaffold used widely as a small-molecule research chemical and synthetic building block. Provided as a high-purity solid, it is used in medicinal chemistry, biochemical assays, and the synthesis of chalcone derivatives. Typical identifiers: CAS 94-41-7; formula C15H12O; molecular weight 208.25 g/mol.
- High purity suitable for research use.
- Useful building block for synthesis of bioactive derivatives.
- Compatible with DMSO; available as solution for screening.
- Supplied with certificate of analysis and safety data for quality and safety.
- Available in small-scale quantities for discovery research.
Medchemexpress LLC Chalcone dibromide | 611-91-6 | 95.0% | 368.06 g/mol | C15H12Br2O | 100 MG
Chalcone dibromide is a dibrominated chalcone derivative supplied as a white to off-white solid for research use. It serves as a versatile synthetic building block and bioactive compound in medicinal chemistry and organic synthesis, commonly used to prepare heterocycles and to evaluate biological activity.
- Dibrominated chalcone useful as a synthetic intermediate.
- Solid, white to off-white appearance for easy handling.
- Reported purity of 95.0% for research applications.
- Available in multiple pack formats including 100 mg and DMSO solutions.
- Structural identifiers provided (SMILES) to support characterization.
Apexbio Technology LLC Naringenin 480-41-1 100mg
Naringenin (CAS 480-41-1) is a small-molecule inhibitor designed to modulate inflammatory and antiviral pathways thereby regulating cellular inflammatory responses and viral replication Naringenin exerts its biological activity primarily through inhibition of the NF- B pathway resulting in reduced inflammatory cytokine production Additionally it demonstrates antioxidative properties by scavenging reactive oxygen species (ROS) In in vitro studies naringenin exhibits inhibition of dengue virus replication with reported IC50 values ranging from approximately 52 64 M to 143 M depending on experimental conditions and viral strains Based on these pharmacological properties naringenin holds research potential in inflammation oxidative stress-related cellular models and dengue virus infection studies
Selleck Chemical LLC Naringenin S2394-25mg
Naringenin (NSC 34875 S-Dihydrogenistein NSC 11855 Salipurol) is a natural predominant flavanone derived from plant food which is considered to have a bioactive effect on human health as antioxidant free radical scavenger anti-inflammatory carbohydrate metabolism promoter and immune system modulator
Cell Signaling Technology Phospho-Akt (Thr450) (D5G4) Rabbit mAb 20 ul
Phospho-Akt (Thr450) (D5G4) Rabbit mAb 20 ul
Cell Signaling Technology Akt (E17K Mutant Specific) (D1T7P) Rabbit mAb 20 ul
Akt (E17K Mutant Specific) (D1T7P) Rabbit mAb 20 ul
Cell Signaling Technology Phospho-Akt Substrate (RXRXXS*/T*) (23C8D2) Rabbit mAb 20 ul
Phospho-Akt Substrate (RXRXXS*/T*) (23C8D2) Rabbit mAb 20 ul
Cell Signaling Technology Phospho-Akt (Thr308) (C31E5E) Rabbit mAb 20 ul
Phospho-Akt (Thr308) (C31E5E) Rabbit mAb 20 ul
Medchemexpress LLC 2-hydroxychalcone | 644-78-0 | 98.1% | 1 G
2-hydroxychalcone is a small-molecule chalcone used as a research reagent; it has reported antioxidant activity and modulates NF-κB and Bcl-2 pathways. The compound is supplied as a light yellow solid with high purity suitable for in vitro biochemical studies.
- Purity: 98.08% (reported).
- Molecular weight: 224.25 g/mol; formula C15H12O2.
- Reported activities: antioxidant, NF-κB inhibition, Bcl-2 downregulation.
- Solubility: DMSO or ethanol up to 100 mg/mL (may require ultrasonication).
- Storage: store at -20°C protected from light; in solvent store at -80°C for long-term stability.
- Available formats: 10 mM solutions in DMSO and solids in 500 mg, 1 g, 5 g, and 10 g quantities.
AdipoGen Phloretin
Chemical. CAS 60-82-2. Formula C15H14O5. MW 274.27. Phloretin is a natural dihydrochalcone, originally identified from the apple tree, and is a metabolite of phlorizin. It has numerous pharmacological effects, including anti-inflammatory, antidiabetic, anticancer, antimicrobial, hepatoprotective, neuroprotective and cytoprotective properties. Phloretin is a potent antioxidant, scavenging peroxynitrite ONOO- and/or suppressing lipid peroxidation, which contributes to the many biological properties. Phloretin has anti-aging and depigmenting effects, making it also attractive for dermatological research and application. Phloretin attacks a number of molecular targets, modulating different intracellular signaling pathways, including NF-kappaB, MAPK, Nrf2, and AMPK. It can modulate Ca2 channels, PKC, GLUTs, SGLTs and other targets. The anticancer potential is based on antiproliferative, proapoptotic, antimetastatic, and antiangiogenic activities.