Macrolide lactams
Medchemexpress LLC D-alanine, N-(1-oxoheptyl)-D-γ-glutamyl-(6R)-6-carboxy-L-lysyl- | 79335-75-4 | 99.9% | 502.56 | C22H38N4O9 | 1mg
FK-565 is a nucleotide oligomerization domain-1 (NOD1) ligand FK-565 induces murine model with arteritis[1]
Medchemexpress LLC N-(1-oxoheptyl)-D-gamma-glutamyl-(6R)-6-carboxy-L-lysyl-D-alanine | 79335-75-4 | 99.9% | 502.56 g/mol | C22H38N4O9 | 10mg
FK-565 is a nucleotide oligomerization domain-1 (NOD1) ligand FK-565 induces murine model with arteritis[1]
Medchemexpress LLC N-(1-oxoheptyl)-D-gamma-glutamyl-(6R)-6-carboxy-L-lysyl-D-alanine | 79335-75-4 | 99.9% | 502.57 g/mol | C22H38N4O9 | 25mg
FK-565 is a nucleotide oligomerization domain-1 (NOD1) ligand FK-565 induces murine model with arteritis[1]
Medchemexpress LLC D-alanine, N-((R)-6-carboxy-N2-(N-(1-oxoheptyl)-D-gamma-glutamyl)-L-lysyl)- | 79335-75-4 | ≥98.0% | 502.57 g/mol | C22H38N4O9 | 5mg
FK-565 is a nucleotide oligomerization domain-1 (NOD1) ligand FK-565 induces murine model with arteritis[1]
Medchemexpress LLC FK 453 | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 25 MG
FK 453 is a research-use adenosine A1 receptor antagonist (compound 1d) characterized by potent activity and a defined chemical profile. It exhibits an IC50 of 17.2 nM and is supplied as a high-purity powder with recommended storage conditions for both powder and solution forms.
- Potent, selective adenosine A1 receptor antagonist (IC50 = 17.2 nM).
- High purity: 99.2%.
- Molecular formula C23H25N3O2 and molecular weight 375.46.
- Available in multiple small-scale package sizes, including 25 mg.
- Storage recommended as powder at -20°C (3 years) or 4°C (2 years).
- In solvent storage guidance: -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical use.
Medchemexpress LLC Fk-453 | 121524-18-3 | 99.2% | 375.46 g·mol⁻¹ | C23H25N3O2 | 100 MG
FK 453 is a potent, selective adenosine A1 receptor antagonist (IC50 = 17.2 nM) supplied as a high-purity small-molecule powder for research use. It includes recommended storage and solvent handling guidance to support reproducible in vitro assays.
- High purity 99.2%.
- Potent adenosine A1 receptor antagonist, IC50 17.2 nM.
- Molecular weight 375.46 g·mol⁻¹; formula C23H25N3O2.
- Recommended solvent DMSO at 100 mg/mL; may require ultrasonication.
- Storage: powder -20°C (up to 3 years), 4°C (up to 2 years); in solvent -80°C (6 months), -20°C (1 month).
- Suitable for in vitro pharmacology and receptor binding studies.
![Medchemexpress LLC (E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243908.png-250.jpg)
Medchemexpress LLC (E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 10 MG
FK 453 is a potent, selective adenosine A1 receptor antagonist intended for research use. It inhibits human A1 receptor activity with an IC50 of 17.2 nM, appears as an off-white to light yellow solid, and also shows activity at adenosine A2B and in primary rat hepatocytes.
- Potent adenosine A1 receptor antagonist (IC50 17.2 nM).
- Additional activity at adenosine A2B (cAMP accumulation IC50 0.98 μM).
- Inhibits NECA-induced glucose production in primary rat hepatocytes (IC50 8.1 μM).
- High purity: 99.2%.
- Molecular weight: 375.46.
- Off-white to light yellow solid; soluble in DMSO (100 mg/mL).
- Storage recommendations: powder -20°C (3 years); in solvent -80°C (6 months).