Methyl Isobutyl Ketone
Medchemexpress LLC Musk ketone | 81-14-1 | 294.31 | 1 ML
Musk ketone is an artificial fragrance and a cytochrome P450 enzyme inducer. It exhibits mutagenic and comutagenic effects in Hep G2 cells and promotes neural stem cell proliferation and differentiation in cerebral ischemia by activating the PI3K/Akt signaling pathway. In the brain, musk ketone provides neuroprotection against stroke injury by inhibiting cell apoptosis.
- Enhances proliferation and differentiation in neural stem cells (NSCs) with increased PI3K/Akt signaling pathway activation.
- Inhibits cell viability of GC cells and prevents colony formation.
- Induces cell cycle arrest and apoptosis in AGS and HGC-27 cells.
- Ameliorates neurological deficit and reduces infarction and cerebral ischemic injury.
- Increases CYP2B activity, protein, and mRNA levels, and boosts CYP1A enzyme activity.
Medchemexpress LLC Musk ketone | 81-14-1 | 294.31 | 100 MG
Musk ketone is a widely used artificial fragrance and a cytochrome P450 enzyme inducer. It shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis. It also inhibits the cell viability of GC cells and induces cell cycle arrest and apoptosis.
- Enhances proliferation and differentiation in neural stem cells
- Increases PI3K/Akt signaling pathway activation
- Ameliorates neurological deficit and reduces infarction and cerebral ischemic injury
- Increases CYP2B activity, protein and mRNA levels, and increases CYP1A enzyme activity
Apexbio Technology LLC Musk ketone 81-14-1 500mg
Musk ketone (CAS 81-14-1) is a small-molecule compound recognized for its modulatory effects on cytochrome P450 enzymes acting as an inducer in cellular systems In Hep G2 cell studies musk ketone has demonstrated mutagenic and cytotoxic properties Notably it promotes neural stem cell proliferation and differentiation under cerebral ischemic conditions primarily via activation of the PI3K/Akt signaling pathway Additionally musk ketone has been observed to confer neuroprotective effects in stroke models by inhibiting apoptosis These characteristics make musk ketone a valuable tool for investigating mechanisms of neural injury and protection in biomedical research
![Medchemexpress LLC 2-Butanone, 4-[4-(β-D-glucopyranosyloxy)phenyl]- | 38963-94-9 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2-Butanone, 4-[4-(β-D-glucopyranosyloxy)phenyl]- | 38963-94-9 | 250 MG
Raspberry ketone glucoside is a melanogenesis inhibitor. It inhibits melanogenesis by activating the IL6/JAK1/STAT3 pathway, inhibiting the transcriptional activity of MITFa, and its downstream expression levels of the TYR and TYRP1a genes. It demonstrates significant whitening activity both in vitro (on B16F10 cells) and in vivo (in a zebrafish model).
- Inhibits melanogenesis through the IL6/JAK1/STAT3 pathway.
- Reduces transcriptional activity of MITFa and expression levels of TYR and TYRP1a genes.
- Shows remarkable whitening activity on B16F10 cells in vitro.
- Reduces internal melanin content and tyrosinase activity in a zebrafish model in vivo.
- Up-regulates mRNA levels of GP130, IL6ST, JAK1, STAT3, and SOCS3b.
- Activates macrophages in zebrafish embryos without affecting embryonic melanogenesis.
Medchemexpress LLC 2-Butanone, 4-[4-(β-D-glucopyranosyloxy)phenyl]- | 38963-94-9 | 1 ML
Raspberry ketone glucoside is a melanogenesis inhibitor that activates the IL6/JAK1/STAT3 pathway, thereby inhibiting the transcriptional activity of MITFa and the downstream expression of TYR and TYRP1a genes. This compound demonstrates significant whitening activity in both B16F10 cells in vitro and in a zebrafish model in vivo.
- Inhibits melanogenesis by activating the IL6/JAK1/STAT3 pathway
- Inhibits transcriptional activity of MITFa
- Reduces downstream expression of TYR and TYRP1a genes
- Demonstrates whitening activity in B16F10 cells and zebrafish models
- Appears as a white to off-white solid
- Purity: 99.52%
- Molecular formula: C16H22O7
- Molecular weight: 326.34
- Soluble in DMSO at 50 mg/mL with ultrasonication
- Can be used as an analytical standard
Apexbio Technology LLC WATERMELON-KETONE-500MG
Watermelon ketone (CAS No 28940-11-6) is a chemical compound studied in the field of biomedical research for its potential therapeutic applications Originating from synthetic processes to mimic natural compounds it is researched for its action on specific cellular pathways particularly those involved in metabolic regulation and oxidative stress In vitro it exhibits significant activity in the nanomolar to low micromolar range demonstrating potential efficacy in biochemical assays Its typical applications include various cell models where it is used to explore its antioxidant properties and possible role in lipid metabolism Animal studies often investigate its effects on metabolic disorders while drug screening programs consider its pharmacological profile for developing new therapeutic agents Experimental concentrations typically depend on the specific research design ensuring adaptability across different scientific investigations
Apexbio Technology LLC WATERMELON-KETONE-1G
Watermelon ketone (CAS No 28940-11-6) is a chemical compound studied in the field of biomedical research for its potential therapeutic applications Originating from synthetic processes to mimic natural compounds it is researched for its action on specific cellular pathways particularly those involved in metabolic regulation and oxidative stress In vitro it exhibits significant activity in the nanomolar to low micromolar range demonstrating potential efficacy in biochemical assays Its typical applications include various cell models where it is used to explore its antioxidant properties and possible role in lipid metabolism Animal studies often investigate its effects on metabolic disorders while drug screening programs consider its pharmacological profile for developing new therapeutic agents Experimental concentrations typically depend on the specific research design ensuring adaptability across different scientific investigations