Benzene and substituted derivatives
3,3'-Diaminodiphenylmethane 98.0+%, TCI America™
CAS: 19471-12-6 Molecular Formula: C13H14N2 Molecular Weight (g/mol): 198.269 MDL Number: MFCD00014777 InChI Key: CKOFBUUFHALZGK-UHFFFAOYSA-N PubChem CID: 146486 IUPAC Name: 3-[(3-aminophenyl)methyl]aniline SMILES: C1=CC(=CC(=C1)N)CC2=CC(=CC=C2)N
2,4,6-Tribromobenzoic Acid 98.0+%, TCI America™
CAS: 633-12-5 Molecular Formula: C7H3Br3O2 Molecular Weight (g/mol): 358.811 MDL Number: MFCD00059882 InChI Key: GHVMJSHEGZYRQL-UHFFFAOYSA-N PubChem CID: 246577 IUPAC Name: 2,4,6-tribromobenzoic acid SMILES: C1=C(C=C(C(=C1Br)C(=O)O)Br)Br
Fluconazole, USP, 98-102%, Spectrum™ Chemical
CAS: 86386-73-4 Molecular Formula: C13H12F2N6O Molecular Weight (g/mol): 306.28 InChI Key: RFHAOTPXVQNOHP-UHFFFAOYSA-N IUPAC Name: 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol SMILES: OC(CN1C=NC=N1)(CN1C=NC=N1)C1=CC=C(F)C=C1F
2-Fluoro-5-methylbenzoic Acid 98.0+%, TCI America™
CAS: 321-12-0 Molecular Formula: C8H7FO2 Molecular Weight (g/mol): 154.14 MDL Number: MFCD00092819 InChI Key: UREMNBHWTNQTMS-UHFFFAOYSA-N Synonym: 2-fluoro-5-methylbenzoicacid,2-fluoro-5-methyl-benzoic acid,6-fluoro-m-toluic acid,2-fluoro-5-methyl benzoic acid,benzoicacid, 2-fluoro-5-methyl,pubchem4750,acmc-1afrc,ksc225s6b,rarechem al bo 1354 PubChem CID: 242829 IUPAC Name: 2-fluoro-5-methylbenzoic acid SMILES: CC1=CC=C(F)C(=C1)C(O)=O
Leflunomide 98.0+%, TCI America™
CAS: 75706-12-6 Molecular Formula: C12H9F3N2O2 Molecular Weight (g/mol): 270.211 MDL Number: MFCD00867593 InChI Key: VHOGYURTWQBHIL-UHFFFAOYSA-N Synonym: leflunomide,arava,leflunomidum,lefunamide,leflunomida,leflunomidum inn-latin,5-methyl-n-4-trifluoromethyl phenyl-1,2-oxazole-4-carboxamide,leflunomida inn-spanish,su 101 pharmaceutical,arava tn PubChem CID: 3899 ChEBI: CHEBI:6402 IUPAC Name: 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide SMILES: CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
Medchemexpress LLC Cholestyramine 50g | 11041-12-6 | 50G
Cholestyramine (Colestyramine) is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol
Selleck Chemical LLC Leflunomide 500mg 75706-12-6 HWA486
Leflunomide (HWA486) is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH). Leflunomide is also an agonist of the AhR. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Leflunomide | 75706-12-6 | C12H9F3N2O2 | 500 MG
Leflunomide is a pyrimidine synthesis inhibitor, primarily functioning by inhibiting dihydroorotate dehydrogenase (DHODH), and is recognized as a disease-modifying antirheumatic agent. This prodrug inhibits the proliferation of mononuclear and T-cells and acts as an inhibitor of several protein tyrosine kinases, with IC50 values ranging from 30 mM to 100 mM in in vitro assays. It also interferes with cell cycle progression and utilizes p53-dependent mechanisms to prevent the expansion of activated and autoimmune lymphocytes.
- Inhibits dihydroorotate dehydrogenase (DHODH)
- Acts as a disease-modifying antirheumatic agent
- Inhibits proliferation of mononuclear and T-cells
- Functions as an inhibitor of several protein tyrosine kinases
- Inhibits p59fyn and p56lck activity in tyrosine kinase assays
- Inhibits calcium mobilization in Jurkat cells
- Prevents expansion of activated and autoimmune lymphocytes
eMolecules 3,3'-Dichlorobenzhydrol | 35190-12-6 | MFCD06201301 | 1g
Oakwood Chemical | 3,3'-Dichlorobenzhydrol | 1g | 537680183 | 022474 | | 35190-12-6 | MFCD06201301 | 253.120 | C13H10Cl2O
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Medchemexpress LLC Leflunomide | 75706-12-6 | 99.8% | C12H9F3N2O2 | 1 ML
Leflunomide is a pyrimidine synthesis inhibitor that acts by inhibiting dihydroorotate dehydrogenase (DHODH), functioning as a disease-modifying antirheumatic agent. It is an immunomodulatory drug that prevents the expansion of activated and autoimmune lymphocytes by interfering with cell cycle progression due to inadequate rUMP production and by utilizing mechanisms involving p53. This product is for research use only.
- Inhibits dihydroorotate dehydrogenase (DHODH)
- Functions as a disease-modifying antirheumatic agent
- Inhibits proliferation of mononuclear and T-cells
- Inhibits several protein tyrosine kinases
- Prevents expansion of activated and autoimmune lymphocytes
Apexbio Technology LLC Leflunomide 75706-12-6 10mM (in 1mL DMSO)
Leflunomide (CAS 75706-12-6) is a small-molecule agonist targeting the aryl hydrocarbon receptor (AHR) pathway It is designed to modulate AHR signaling thereby enhancing regulatory T cell (Treg) numbers altering inflammatory cytokine profiles and influencing immune responses Leflunomide exerts its biological activity primarily through metabolic conversion to its active metabolite Teriflunomide (A771726) which mediates immunosuppressive effects It enhances IL-10 production and suppresses IL-17 and IL-23 secretion In cell-based studies leflunomide demonstrates anti-proliferative efficacy in human medullary thyroid carcinoma cells (MTC-TT) with IC50 values ranging from approximately 30 to 50 M depending on specific assay conditions Based on these pharmacological properties leflunomide holds research potential in ischemia-reperfusion renal injury sepsis-induced intestinal oxidative stress and tumor proliferation inhibition models
Medchemexpress LLC Cholestyramine | 11041-12-6 | 435.1 g/mol | C27H47ClN2 | 10 G
Cholestyramine is a chloride-form anion-exchange bile acid binding resin supplied as a white to off-white powder for research and analytical use. It sequesters intestinal bile acids, reducing bile acid absorption and driving increased bile acid synthesis from cholesterol, and is used in biochemical studies and in vitro bile acid removal.
- Binds intestinal bile acids effectively.
- Supplied as a powder for easy suspension and handling.
- Contains specified chloride content and exchange capacity for predictable performance.
- Certificate of analysis reports chloride content, loss on drying, and exchange capacity.
- Suitable for biochemical and physiological research involving bile acid sequestration.
eMolecules 3-(3-Aminobenzyl)phenylamine | 19471-12-6 | MFCD00014777 | 100mg
Toronto Research Chemicals | 3-(3-Aminobenzyl)phenylamine | 100mg | 601588567 | A100820 | | 19471-12-6 | MFCD00014777 | 198.269 | C13H14N2
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eMolecules Building Block Tool
Chemscene 6 12-Dibromochrysene | 5g | CS-W011747 | 98% | 131222-99-6 | MFCD00092281 | 386 09 | C18H10Br2
Chemscene | 6 12-Dibromochrysene | 5g | CS-W011747 | 98% | 131222-99-6 | MFCD00092281 | 386 09 | C18H10Br2
Chemscene 6 12-Dibromochrysene | 25g | CS-W011747 | 98% | 131222-99-6 | MFCD00092281 | 386 09 | C18H10Br2
Chemscene | 6 12-Dibromochrysene | 25g | CS-W011747 | 98% | 131222-99-6 | MFCD00092281 | 386 09 | C18H10Br2