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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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h/m FASN-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FASN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fatty acid synthase (FASN) The shRNA has been validated to meet or exceed 70% FASN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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FGF-2 is a member of the fibroblast family involved in bone healing cartilage repair bone repair and nerve regeneration FGF-2 is also a mitotic promoter that accelerates cell proliferation FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway For example FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage respectively[1] FGF-2 is also a known carcinogen in GBM which contributes to glioma growth and vascularization[2] Animal-Free FGF-2 Protein Mouse (His) consists of 144 amino acids produced by E coli with tag free This product is for cell culture use only
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Mouse CD86 mRNA encodes CD86P primarily expressed on antigen-presenting cells It binds to CD28 and CTLA-4 receptors on T cells to regulate T-cell activation and immune responses The interaction between CD86 and CD28 promotes T-cell activation and proliferation whereas its binding to CTLA-4 inhibits T-cell activity maintaining immune system balance Expression and function of CD86 are critical in various immune responses including infections tumor immunity and autoimmune diseases CD86 activity may offer novel therapeutic strategies for various immune-related disorders EZ Cap Mouse CD86 mRNA (m1 HA tag) is provided at 1 mg/mL expressing mouse-derived CD86 cytokine fused with HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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2OH-BNPP1 is a small-molecule inhibitor of the serine/threonine kinase BUB1, used as a research tool in oncology and cell-cycle studies. It is supplied as a white to off-white solid and as a DMSO solution, and is characterized by high reported purity and defined storage and solubility conditions.
Inhibitor of BUB1 kinase for research applications.
Reported purity 99.65% (analytical grade).
Molecular formula C16H19N5O; molecular weight 297.35 g/mol.
Physical form: white to off-white solid; also available as a DMSO solution.
Solubility: DMSO 100 mg/mL (336.30 mM); in vivo formulations and solubility notes provided.
Storage: powder stored at -20°C (long term) or 4°C; solutions recommended at -80°C for long-term storage.
Available in small research quantities, e.g., 25 mg, 50 mg, and 100 mg.
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R 59-022 is a small-molecule diacylglycerol kinase (DGK) inhibitor that elevates diacylglycerol-dependent protein kinase C activity and acts as a 5-HT receptor antagonist. It is supplied with high reported purity and is commonly used in biochemical and cell-signaling research to investigate DAG/PKC-mediated pathways and receptor pharmacology.
High purity suitable for research applications.
Provided as a 10 mM solution in DMSO for immediate use.
Also available as a solid for custom formulation.
Molecular weight 459.58 g/mol and chemical formula C27H26FN3OS.
Effective probe for studying DGK and PKC signaling pathways.
Soluble in common organic solvents, enabling diverse assay formats.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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