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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK). purity: 99%
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This nucleoside phosphoramidite monomer is used for synthesizing locked nucleic acid (LNA) analog oligonucleotides, acting as a building block for antisense oligonucleotides (ASOs) to target complementary RNA sequences. Its 2',4'-constrained ethyl (cEt) modification enhances hybridization affinity and mismatch discrimination with RNA, improving oligonucleotides' resistance to exonuclease digestion and enabling gene expression regulation.
Synthesizes locked nucleic acid (LNA) analog oligonucleotides.
Enhances RNA hybridization affinity and mismatch discrimination.
Improves oligonucleotide resistance to exonuclease digestion.
Facilitates RNase H-dependent mRNA degradation.
Used in antisense drug development and gene research.
Improves qPCR probe/primer stability and melting temperature.
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P-CAB agent 2 hydrochloride is a potent and orally active potassium-competitive acid blocker and a gastric acid secretion inhibitor. It inhibits H+/K+-ATPase activity with an IC50 value of <100 nM. It also inhibits the hERG potassium channel with an IC50 value of 18.69 μM. This agent shows no acute toxicity and inhibits histamine-induced gastric acid secretion.
Potent and orally active potassium-competitive acid blocker.
Inhibits gastric acid secretion.
Inhibits H+/K+-ATPase activity with an IC50 value of <100 nM.
Inhibits hERG potassium channel with an IC50 value of 18.69 μM.
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p-Nitrophenyl Sulfate Potassium is a chromogenic substrate for arylsulfatase. It is released by arylsulfonase cleavage, and the activity of arylsulfonase can be quantitatively determined by colorimetric detection at 400 nm.
Chromogenic substrate for arylsulfatase
Useful for quantitative determination of arylsulfonase activity
Colorimetric detection at 400 nm
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p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. This orally active androgen receptor antagonist can affect the development and function of the male reproductive system by inhibiting androgen binding and transcriptional activity. High serum concentrations of p,p'-DDE may also be a risk factor for type 2 diabetes in women.
Major and persistent metabolite of DDT
Orally active androgen receptor antagonist
Affects development and function of male reproductive system
Inhibits androgen binding to the androgen receptor
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amyloid P-IN-1 is utilized in the research of diseases or disorders characterized by the depletion of serum amyloid P component (SAP). These conditions include amyloidosis, Alzheimer's disease, type 2 diabetes mellitus, and osteoarthritis. It is intended for research use only and not for sale to patients.
Used in research for diseases involving serum amyloid P component (SAP) depletion.
Has a purity of 99.59%.
Available in various quantities as solid or in DMSO solution.
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