Phenols
Apexbio Technology LLC 4-Ethylphenol 123-07-9 100mg
4-Ethylphenol (CAS 123-07-9) is a volatile phenolic compound predominantly produced through the microbial decarboxylation and reduction of p-coumaric acid during fermentation and other metabolic processes It is frequently utilized to investigate the microbial enzymatic pathways underlying aromatic compound metabolism In biomedical research 4-ethylphenol serves as a model molecule for studying the interplay between microbial metabolites and host metabolic networks as well as for the identification of microbial biomarkers in health and disease Its applications extend to experiments addressing the dynamics of microbial communities and host-microbe interactions
Apexbio Technology LLC PTP Inhibitor I 2491-38-5 10mM (in 1mL DMSO)
PTP Inhibitor I (CAS 2491-38-5) is a small molecule inhibitor targeting protein tyrosine phosphatases (PTPs) specifically SHP-1 and PTP1B with inhibition constants (KI) of 43 M and 42 M respectively As an -bromoacetophenone derivative it acts as a neutral phosphotyrosine mimetic covalently modifying the active site cysteine of PTPs Structure-activity studies indicate that modifications to the phenyl ring moderately affect potency while para-substituted peptidyl groups can enhance both potency and selectivity PTP Inhibitor I is utilized in vitro for mechanistic studies of PTP function related to diabetes neurodegenerative disorders immune regulation and pathogen virulence Animal and clinical data are not available
![Medchemexpress LLC Benzamide, 2-chloro-5-[3-[(3-hydroxypropyl)amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethy-1)- | 345303-91-5 | 98.2% | 455.46 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385590-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzamide, 2-chloro-5-[3-[(3-hydroxypropyl)amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethy-1)- | 345303-91-5 | 98.2% | 455.46 | 25 MG
AZD9056 hydrochloride is a selective and orally active inhibitor of P2X7, a receptor that plays a significant role in inflammatory and pain-causing diseases. This compound is intended for research use only.
- Blocks P2X7 receptors with an IC50 of 11.2 nM in HEK-hP2X7 cell lines, demonstrating high selectivity for the P2X7 receptor.
- Exhibits an inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells.
- Weakly inhibits BCRP-mediated transport of methotrexate (IC50=92 μM).
- Displays pain-relieving and anti-inflammatory effects.
- Reverses the upregulated expression of interleukin (IL)-1β, IL-6, tumor necrosis factor-α (TNF-α), matrix metalloproteinase-13 (MMP-13), substance P (SP), and prostaglandin E2 (PGE2) induced by MIA in cartilage tissues.
Cayman Chemical 8piperazin1ylIsoquinoline hy
A synthetic intermediate useful for pharmaceutical synthesis.
Apexbio Technology LLC 8-Bromo-cGMP, sodium salt 51116-01-9 25mg
8-Bromo-cGMP sodium salt (CAS 51116-01-9) is a membrane-permeable analog of cyclic GMP that functions as an activator of protein kinase G (PKG) By mimicking endogenous cGMP it modulates intracellular signaling pathways notably influencing Ca2 channel activity Studies indicate that 8-Bromo-cGMP sodium salt can suppress macroscopic ionic currents and reduce insulin secretion under high K stimulation Due to its role in signal transduction and vascular function this compound is frequently employed in research addressing nociceptive modulation and vascular biology
eMolecules 76045-71-1 | 3-Amino-5-hydroxybenzoic acid | Combi-Blocks | MFCD06797571 | 153.137 | C7H7NO3 | 95.000 | Nc1cc(O)cc(c1)C(O)=O | 1g | 205413561
3-Amino-5-hydroxybenzoic acid | Combi-Blocks | 76045-71-1 | MFCD06797571 | 153.137 | C7H7NO3 | 95.000 | Nc1cc(O)cc(c1)C(O)=O | 1g | 205413561
Cambridge Isotope Laboratories 2 4 5-Trichlorophenol (ring-D2 97-98%) 0 1 g
2 4 5-Trichlorophenol (ring-D2 97-98%) 0 1 g
Medchemexpress LLC 2-Hydrazinobenzothiazole | 615-21-4 | 99.95% | C7H7N3S | 100 G
This compound, 2-Hydrazinobenzothiazole, is a potent IDO1 inhibitor with an IC50 of 8 μM. It interacts with the IDO1 haem through hydrazine and has potential for immune system related diseases research. It is supplied with a purity of 99.95%.
- Potent IDO1 inhibitor (IC50 of 8 μM)
- Interacts with IDO1 haem via hydrazine
- Suitable for immune system related diseases research
- Purity of 99.95%
- Solid appearance
- Molecular weight: 165.22
- Chemical formula: C7H7N3S
- CAS number: 615-21-4
Cambridge Isotope Laboratories 4 4-DDE (ring-13C12 99%) 100 ug/mL in nonane 1 2 mL
4 4-DDE (ring-13C12 99%) 100 ug/mL in nonane 1 2 mL
eMolecules 1261779-40-1 | AstaTech | 2-CHLORO-6-(TRIFLUOROMETHOXY)BENZONITRILE | 1g | 335877287 | 55872 | 95 | MFCD18393805 | 221.56 | C8H3ClF3NO
Ambeed | Sodium naphthalen-2-yl hydrogenphosphate | 1g | 586458318 | A908657 | 14463-68-4 | MFCD00065914 | 246.134 | C10H8NaO4P
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