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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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Delapril hydrochloride is the hydrochloride salt of delapril, an angiotensin-converting enzyme (ACE) inhibitor used in cardiovascular research and preclinical studies. The compound is provided both as a ready-to-use 10 mM solution in DMSO (1 mL) and in solid quantities. Typical reported purity is 98.0% and the molecular weight is 489.00 g·mol⁻¹. Store and handle according to supplier safety data.
ACE inhibitor used in cardiovascular research.
Available as 10 mM solution in DMSO (1 mL) and as solid quantities.
High reported purity, 98.0%.
Molecular weight 489.00 g·mol⁻¹.
CAS number 83435-67-0 for unambiguous identification.
Store solid at 4°C; store solution frozen for long-term stability.
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AZD9056 hydrochloride is a selective orally active inhibitor of P2X7, which plays a significant role in inflammation and pain-causing diseases. It is for research use only and not sold to patients.
Selective orally active inhibitor of P2X7.
Blocks P2X7 receptors with an IC50 of 11.2 nM in HEK-hP2X7 cell line.
Exhibits high selectivity for the P2X7 receptor.
Has an inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells.
Weakly inhibits BCRP-mediated transport of methotrexate (IC50=92 μM).
Exerts pain-relieving and anti-inflammatory effects in vivo.
Reverses upregulated expression of IL-1β, IL-6, TNF-α, MMP-13, SP, and PGE2 induced by MIA in cartilage tissues.
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Vernakalant hydrochloride is a research chemical that acts as a mixed voltage- and frequency-dependent sodium channel blocker and an atria-preferred potassium channel blocker, used to investigate atrial electrophysiology and arrhythmia mechanisms. It is supplied in solid and DMSO solution formats and is characterized by defined molecular properties for in vitro studies.
High purity (99.33%).
Available as solid and 10 mM DMSO solution.
Suitable for in vitro electrophysiology and pharmacology studies.
Molecular formula C20H32ClNO4; molecular weight 385.93 g·mol⁻¹.
For research use only; not for human or veterinary use.
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