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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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IL-1RAcP is a co-receptor for IL1RL2 IL1R1 and IL1RL1 in the IL-36 IL-1 and IL-33 signaling system respectively IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process[1][2] IL-1RAcP/IL-1 R3 Protein Mouse (HEK293 Fc) is a recombinant mouse IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells
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Mexiletine hydrochloride (CAS 5370-01-4) is a small molecule classified as a Class IB anti-arrhythmic agent It modulates cardiac electrophysiological activity primarily by inhibiting voltage-gated sodium channels resulting in decreased inward sodium currents during the cardiac action potential Through this mechanism mexiletine HCl stabilizes cardiac cell membranes and suppresses abnormal electrical activity This compound is frequently utilized in research to study sodium channel function cardiac arrhythmia models and the pharmacodynamics of anti-arrhythmic interventions
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SS-208 (AVS100) is a selective histone deacetylase 6 (HDAC6) inhibitor for research use, with a reported IC50 of 12 nM and a molecular weight of 344.15 g·mol⁻1. It has demonstrated anti-tumor activity in melanoma models and is provided as a high-purity solid for preclinical and biochemical studies.
Selective HDAC6 inhibition with low nanomolar potency.
High reported purity suitable for research applications.
Applicable to cell-based and biochemical assays.
Provided as a solid for easy handling and dissolution.
Includes product datasheet and safety data documentation.
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Lansoprazole sodium is a small-molecule inhibitor targeting gastric H /K -ATPase and several human cytochrome P450 (CYP) isoforms including CYP2C9 and CYP2C19 It is designed to inhibit acid secretion by selectively modulating H /K -ATPase activity in parietal cells and to modulate CYP-mediated metabolism pathways Lansoprazole sodium exerts its biological activity primarily through inhibition of its targets In human liver microsome studies it inhibits CYP2C9 and CYP2C19 with Ki values of approximately 21 M and 1 M respectively its inhibitory effect on CYP2D6 and CYP3A4 is weaker with IC values above 200 M Based on these pharmacological properties Lansoprazole sodium holds research potential in the investigation of gastric acid secretion disorders and drug drug interaction profiles involving CYP-mediated metabolism
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