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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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Sodium lauroyl glutamate is an anionic amino acid surfactant primarily used in cleaning products. While it has the potential for irritant contact dermatitis, it also exhibits possible anti-irritating properties in surfactant mixtures on human skin. A 1% w/w solution demonstrates low irritation and has a pH value of 5.41.
Anionic amino acid surfactant
Mild surfactant
Used mainly in cleaning products
Exhibits possible anti-irritating potential in surfactant mixtures
Low irritation to nude mouse skin at 1% w/w solution
1% w/w solution has a pH value of 5.41
Appears as a white to off-white solid
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Small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used as a research tool to study ferroptosis and inflammation. Reported activity includes an approximate pEC50 of 4.7 and an ability to increase GPX4 activity in biochemical assays. Supplied as a solid with good solubility in DMSO for assay preparation.
Allosteric activation of glutathione peroxidase 4 with reported pEC50 ≈ 4.7.
Shown to increase GPX4 activity to about 150% in biochemical assays.
Useful for probing ferroptosis and inflammation pathways in preclinical research.
Supplied as a solid with high DMSO solubility for convenient dilution and assay use.
Vendor-reported molecular formula and molecular weight provided for analytical reference.
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ULK-101 is a potent, selective small-molecule inhibitor of ULK1 used in cellular and biochemical research to suppress autophagy and sensitize cancer cells to nutrient stress.
Potent ULK1 inhibition (IC50 = 1.6 nM) with lower activity on ULK2 (IC50 = 30 nM).
High purity suitable for research applications (99.91%).
Available as a powder in multiple pack sizes, including 25 MG, and as DMSO solution formats.
Storage-stable when kept at recommended temperatures for powder and solutions.
Molecular weight 460.45 and molecular formula C22H16F4N4OS.
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UK-101 is a potent, selective inhibitor of the immunoproteasome β1i (LMP2) subunit used as a biochemical probe to study immunoproteasome activity and apoptosis-related pathways.
Potent LMP2 inhibition (IC50 ≈ 104 nM).
High selectivity versus β1c and β5 subunits.
High purity suitable for research use (≈99.6%).
Soluble in DMSO (≈7.3 mg/mL); may require warming or sonication.
Supplied in small quantities appropriate for laboratory assays.
Commonly used in biochemical assays and apoptosis research.
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Pigment Yellow 101 is a yellow bis-azomethine pigment that exhibits solid-state fluorescence with excitation/emission at 411 nm/512 nm. This product is available as a commercial colorant.
Yellow bis-azomethine pigment
Excitation/emission: 411 nm/512 nm
Exhibits solid-state fluorescence
Available as a commercial colorant
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