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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
The Citrate Synthase Assay Kit contains all the required reagents (including a positive control enzyme) for a fast and simple measurement of citrate synthase activity in a whole cell extract or in isolated mitochondria. In addition the kit enables testing of the intactness of the mitochondrial inner membrane.
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HO-PEG-CH2COOH (MW 35,000) is a carboxy-terminated polyethylene glycol (PEG) polymer used as a hydrophilic spacer for PROTAC synthesis and other bioconjugation applications. The polymer features a hydroxyl terminus and a carboxymethyl terminus, providing a reactive carboxylic acid for coupling chemistries. Supplied as a white to off-white solid with ~95.0% purity; recommended storage is -20°C under nitrogen.
High molecular weight PEG spacer (35,000 Da) for increased solubility and linker length.
Carboxy-terminated for straightforward amide or ester coupling.
Hydroxyl-terminated opposite end for orthogonal functionalization.
Solid powder form is easy to handle and weigh for synthesis workflows.
Stable under recommended storage; in solvent store at -80°C for extended stability.
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ARL67156 trisodium is a small-molecule research inhibitor of ecto-ATPase (NTPDase) enzymes, provided as the trisodium salt in solid form. It is used to study nucleotide hydrolysis and related pathologies such as calcific aortic valve disease and asthma.
Selective inhibitor of NTPDase1 (CD39), NTPDase3, and NPP1.
Reported Ki values approximately 11 μM (NTPDase1), 18 μM (NTPDase3), and 12 μM (NPP1).
High reported purity (99.94%).
Molecular weight about 785.05 g·mol-1 and exact formula C15H21Br2N5Na3O12P3.
Supplied as a solid trisodium salt, available in small research pack sizes.
Store sealed and away from moisture at -20°C; in solution, store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Fmoc-NH-PEG1-CH2COOH is an Fmoc-protected PEG1 linker used as a cleavable linker for antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker. The compound is supplied as a white powder with reported high purity and is available in multiple pack sizes, including a 5 G pack.
Fmoc-protected amine with a PEG1 spacer and terminal carboxylic acid.
Used as a cleavable linker in ADC and PROTAC syntheses.
Supplied as a white powder; multiple pack sizes available.
Reported high purity suitable for research applications.
Chemical identifiers: CAS 260367-12-2; molecular weight 341.36; formula C19H19NO5.
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Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2]
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cGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. It activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators.
Endogenous second messenger in metazoans.
Triggers interferon production in response to cytosolic DNA.
Activates stimulator of interferon genes (STING).
Activates a signaling cascade leading to the production of type I interferons and other immune mediators.
Promotes the antigen-specific proliferation capacity of spleen cells in mice.
Directly activates murine and human dendritic cells *in vitro*.
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Clomiphene citrate (CAS 50-41-9) is a small-molecule modulator targeting estrogen receptors (ER) It is designed to selectively modulate ER-mediated signaling thereby influencing estrogen-dependent cellular pathways Clomiphene citrate exerts its biological activity primarily through competitive inhibition at estrogen receptors It demonstrates both antiestrogenic and estrogenic activities depending on tissue context Based on these pharmacological properties clomiphene citrate holds research potential in the investigation of estrogen receptor-mediated transcriptional regulation cellular proliferation and differentiation as well as hypothalamic-pituitary-gonadal axis regulation and ovarian follicular maturation in reproductive biology studies
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