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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ACEPROMAZINE MALEATE is a dopamine receptor antagonistpurity: 99%
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Rosiglitazone maleate (CAS 155141-29-0) is the maleate salt formulation of rosiglitazone a thiazolidinedione compound targeting the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR ) By selective activation of PPAR rosiglitazone increases insulin sensitivity of peripheral tissues facilitating glucose uptake and reduction of blood glucose levels Due to its insulin-sensitizing activity rosiglitazone maleate serves as an important research tool in diabetes and metabolic syndrome investigations However recent clinical studies also report associations with adverse cardiovascular events fluid retention and anemia underscoring considerations for risk-benefit evaluation in ongoing research
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WAY-100635 maleate is the maleate salt of WAY-100635, a potent and selective 5-HT1A receptor antagonist used for pharmacology and receptor-binding research. It is provided as a high-purity analytical standard suitable for in vitro and in vivo studies.
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Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
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Quipazine maleate is a laboratory chemical from MedChemExpress, identified by catalog number HY-B1495 and CAS number 5786-68-5. It is intended for research use only and for experienced personnel. This product is classified as toxic if swallowed, requiring careful handling.
Used for laboratory research and manufacturing of substances.
Stable under recommended storage conditions.
Shipping at room temperature is acceptable if less than 2 weeks.
Recommended storage at 4°C, sealed, away from moisture and light.
If in solvent, store at -80°C for 6 months or -20°C for 1 month.
Appearance is a solid.
Melting/freezing point is 151-154 °C.
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Menadiol Diacetate (CAS 573-20-6) is a synthetic derivative of vitamin K investigated for its regulatory effects on cellular signaling pathways and enzyme activities In experimental studies Menadiol Diacetate has been shown to induce S phase arrest in the cell cycle leading to apoptotic cell death This compound is utilized in research focused on cancer and related diseases providing a tool for exploring mechanisms of cell proliferation and apoptosis in vitro
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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A triterpene with antiviral and hepatoprotective activities; inhibits SFV replication in virus-infected Huh7 cells (IC50 = 9.1 µM); improves hepatic function in various rat models of hepatitis at 20 mg/kg
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Menadiol Diacetate (Vitamin K4 Acetomenaphthone Kapilin) is a synthetic hydrophilic menadione compound which is clinically used as hemostasis medicine It induces caspase-3-related apoptosis pathway via mitochondrial dysfunction and DNA fragmentation
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Ethynodiol diacetate is a click chemistry reagent that contains an Alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
A synthetic progestogen; prevents the development of osteoporosis in ovariectomized rats at 9 µg/animal per day; inhibits copulatory ovulation in rabbits
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Chemical. CAS 596-09-8. Formula C24H16O7. MW 416.38. Synthetic. FDA is a non-fluorescent hydrophobic fluorescein derivative that can pass through the cell membrane whereupon intracellular esterases hydrolyze the diacetate group producing the highly fluorescent product fluorescein. The fluorescein molecules accumulate in cells that possess intact membranes so the green fluorescence can be used as a marker of cell viability. Cells that do not possess an intact cell membrane or an active metabolism may not accumulate the fluorescent product and therefore do not exhibit green fluorescence. FDA may be used in combination with PI staining as the non-viable cells take up the PI and stain dead cells red whereas viable cells do not take up the PI and should only stain green. This 2-color separation of non-viable and viable cells may provide a more accurate quantitation of cell viability than single color analysis.
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