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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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YB-0158 is a reverse-turn peptidomimetic and a potent targeting agent for colorectal cancer stem cells. It works by disrupting Sam68-Src interactions and inducing apoptosis in colorectal cancer cells, demonstrating anti-cancer activities.
Significantly increases apoptosis in colorectal cancer cells, as shown by activated Caspase-3/7 detection assays.
Decreases CBP recruitment at the promoter of Wnt/beta-Catenin target genes LGR5 and MYC in HT29 cells.
Displays an EC50 (1.64 μM) in cultured MC38 cells.
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Selective FLT3 kinase inhibitor for laboratory research. Potent inhibitor (IC50 = 40 nM) used in preclinical studies to probe FLT3-driven signaling and apoptosis. Supplied as a high-purity small molecule with supporting datasheet, COA, and SDS; not for human use.
Potent FLT3 inhibition (IC50 40 nM).
High purity suitable for research (≈98.5%).
Molecular formula C26H29N7O2; molecular weight 471.55.
Soluble in DMSO for biological assays.
Available in multiple small-scale pack sizes for preclinical work.
Provided with datasheet, certificate of analysis, and safety data sheet.
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Crocetin dialdehyde is a non-volatile apocarotenoid obtained by the action of the plastidic enzyme CCD2 over the carotenoid zeaxanthin in saffron. It can be converted into Crocetin by aldehyde dehydrogenases (ALDHs) and has shown no effect on the liver in mice.
Purity: 99.21%
Appearance: Solid
Color: Orange to reddish brown
Initial source: Plants Iridaceae Crocus sativus Linn.
For research use only.
Shown no effect on the liver in mice.
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Rhodamine 123 is a green-fluorescent xanthene dye used as a probe of mitochondrial membrane potential and as a general fluorescent tracer in cell biology and bioanalytical assays. It is supplied as a stable solid for preparation of stock solutions for microscopy, flow cytometry, and fluorescence spectroscopy.
High purity for reproducible fluorescence.
Cell-permeable cationic dye that accumulates in mitochondria.
Suitable for microscopy, flow cytometry, and plate-reader assays.
Stable solid form for convenient storage and stock solution preparation.
Compatible with common fluorescent imaging and spectroscopic workflows.
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(S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol is a -Adrenoceptor ( -Adrenergic Receptor) antagonist with log Kd values of -8 16 -9 08 and -6 93 for 1 2 and 3 respectively
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KNT-127 is a selective, brain-penetrant δ-opioid receptor agonist used in neuroscience research. It exhibits high affinity for the δ receptor and functional bias toward cAMP signaling, and has demonstrated antidepressant- and anxiolytic-like effects in animal models.
Selective δ-opioid receptor agonist with high affinity (Ki δ ≈ 0.16 nM).
Biased signaling toward cAMP over beta-arrestin pathways.
Brain-penetrant compound suitable for in vivo studies.
High purity solid (99.6%) available in milligram quantities.
Recommended storage: powder at -20°C for long-term stability.
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(S)-(-)-Propranolol hydrochloride is a chiral antihypertensive agent with approximately 100-fold higher potency than its R-enantiomer. It is used for studies on hypertension, angina pectoris, and arrhythmia. It appears as a white to off-white solid.
Chiral antihypertensive agent
Approximately 100-fold higher potency than its R-enantiomer
Can be used for studies on hypertension, angina pectoris, and arrhythmia
Exhibits enantiospecific SERS spectral features and peak intensity ratios when analyzed using an NPGB/EC-SERS platform, enabling label-free chiral differentiation
For research use only
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Adenosine dialdehyde (AdOx) has been identified as an indirect methyltransferase inhibitor. Histone methyltransferases are a group of enzymes that catalyze the methylation of histone lysine and arginine by adding methyl groups to specific histone arginine or lysine residues. Other sizes are available. Please inqury us for quote.
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