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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
2-Deoxy-D-ribose (CAS 533-67-5) is a naturally occurring pentose analog commonly utilized in organic synthesis and biomedical research This compound exerts biological activity by triggering apoptosis through suppression of glutathione synthesis and enhancement of cellular glutathione export sensitizing cells toward oxidative stress-induced apoptosis Additionally 2-deoxy-D-ribose serves as an intermediate in the stereoselective preparation of dipyrrolyl alkanols from pyrrole derivatives in reactions catalyzed by montmorillonite KSF clay
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YB-0158 is a reverse-turn peptidomimetic and a potent targeting agent for colorectal cancer stem cells. It works by disrupting Sam68-Src interactions and inducing apoptosis in colorectal cancer cells, demonstrating anti-cancer activities.
Significantly increases apoptosis in colorectal cancer cells, as shown by activated Caspase-3/7 detection assays.
Decreases CBP recruitment at the promoter of Wnt/beta-Catenin target genes LGR5 and MYC in HT29 cells.
Displays an EC50 (1.64 μM) in cultured MC38 cells.
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2'-Deoxy-2'-fluorocytidine is a nucleoside analog that acts as a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. It can also synergistically enhance the antiviral effects of T705 against CCHFV replication.
Potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication.
Acts synergistically with T705 to increase antiviral effects on CCHFV replication.
Available in various quantities and forms: solid, and solutions (e.g., 10 mM * 1 mL in Water).
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Bupropion hydrochloride (CAS 31677-93-7) is a small-molecule aminoketone that acts as a dual inhibitor of norepinephrine and dopamine reuptake with IC values of 6 5 0 6 M and 3 4 0 4 M respectively It is widely utilized in research for its established roles in modulating monoaminergic neurotransmission associated with depression and smoking cessation In cellular studies bupropion hydrochloride has been shown to decrease cell viability in SH-SY5Y neuroblastoma cells selectively induce endoplasmic reticulum stress and activate JNK pathways leading to caspase 3-dependent apoptosis Additionally it has been reported to downregulate tyrosine hydroxylase expression impacting dopamine biosynthesis
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