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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK, functioning as a potent and novel CDK6-selective small-molecule degrader. It causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.
Potent and novel CDK6-selective small-molecule degrader
Induces G1 cell-cycle arrest in AML cell lines
Causes anti-proliferative effect in CDK6-dependent AML cell lines
Does not significantly increase apoptosis
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Ascorbate oxidase, Cucurbit sp., also known as vitamin C oxidase, is a REDOX enzyme involved in the regulation of the extracellular matrix. It catalyzes the reaction of ascorbic acid and oxygen to produce dehydroascorbic acid.
REDOX enzyme involved in the regulation of extracellular matrix.
Catalyzes the reaction of ascorbic acid and oxygen to produce dehydroascorbic acid.
For research use only.
Available in 100 U, 500 U, and 1000 U quantities.
Purity (Enzyme Activity) is ≥100 U/mg solid.
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Sulfalene-13C6 is a 13C6 labeled form of Sulfalene, which is known as an antimalarial agent and a long-acting sulfonamide antibacterial. This compound is suitable for various laboratory applications and the manufacture of substances.
Used as a tracer
Functions as an internal standard for quantitative analysis
Suitable for NMR, GC-MS, or LC-MS applications
Identified for use as a laboratory chemical
Applicable in the manufacture of substances
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Oxacillin-13C6 sodium is the 13C6 labeled Oxacillin sodium salt, which is a narrow-spectrum β-lactam antibiotic of the penicillin class. This compound is intended for research use only.
Used as a tracer
Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Propranolol glycol is an endogenous metabolite provided as a high-purity analytical reference for laboratory research. Supplied with supporting documentation, it is intended for use as a reference standard in analytical methods development, compound identification, and biological studies.
High purity (99.3%).
Supplied as an analytical reference standard for research use.
Provided with certificate of analysis (COA), safety data sheet (SDS), and datasheet.
Available in small mg package sizes suitable for analytical workflows.
Suitable for analytical method development and biochemical studies.
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Rhodamine 123 (RH-123 R-22420) is a fluorescent cationic dye used to label mitochondria in living cells Rhodamine 123 inhibits ADP-stimulated respiration of mitochondria with Ki 12 M and ATPase activity of inverted inner membrane vesicles with Ki of 126 M and partially purified F1-ATPase with Ki of 177 M
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