Aminobenzoic acids and derivatives
Apexbio Technology LLC AC 45594 13037-86-0 50mg
AC 45594 (CAS 13037-86-0) is a synthetic inverse agonist of steroidogenic factor-1 (SF-1) a constitutively active nuclear receptor regulating adrenal/gonadal differentiation and steroid hormone biosynthesis By binding SF-1 it inhibits SF-1 mediated transcription and modulates steroidogenic gene expression In human adrenal cortical H295R cells AC 45594 suppresses SF-1 transcriptional activity with an IC of 50 100 nM reduces cyclic AMP induced StAR mRNA and protein expression and dose-dependently decreases proliferation while promoting apoptosis in SF-1 overexpressing cells These properties support its research use in studying SF-1 dependent regulation of steroidogenesis proliferation and survival in adrenal and endocrine models
Medchemexpress LLC Amino-peg3-c2-acid | 784105-33-5 | MFCD21607085 | 99.9% | 221.25 g·mol⁻¹ | C9H19NO5 | 1 G
Amino-PEG3-C2-acid is a bifunctional PEG-based linker with terminal amino and carboxylic acid groups, designed for conjugation chemistry in PROTAC and antibody-drug conjugate synthesis. Intended for research use only.
- Short PEG spacer with three ethylene glycol units.
- Terminal amino and carboxylic acid functional groups.
- Suitable for PROTAC and ADC linker synthesis.
- High purity (99.94%).
- Available in pack sizes including 1 g.
Medchemexpress LLC Acid-PEG2-SS-PEG2-acid | 1807539-10-1 | 95.0% | 386.48 | C14H26O8S2 | 50 MG
Acid-PEG2-SS-PEG2-acid is a cleavable four-unit polyethylene glycol (PEG) linker that contains a central disulfide bond and terminal carboxylic acids. It is used as a spacer in antibody-drug conjugate (ADC) synthesis and general bioconjugation research, providing controlled release via reductive cleavage and improved solubility from PEGylation.
- Cleavable disulfide (SS) linkage enabling reductive release.
- Two PEG2 units provide hydrophilicity and spacing.
- Terminal carboxylic acids for straightforward conjugation chemistry.
- Suitable for ADC linker design and other bioconjugation applications.
- Available in multiple pack sizes for research use only.
Chemscene 2 5-Dimethoxyaniline | 1kg | CS-W020681 | 98% | 102-56-7 | MFCD00008368 | 153 18 | C8H11NO2
Chemscene | 2 5-Dimethoxyaniline | 1kg | CS-W020681 | 98% | 102-56-7 | MFCD00008368 | 153 18 | C8H11NO2
Medchemexpress LLC Ac-GpYLPQTV-NH2 acetate | 99.4% | 897.91 (free base) | 1 MG
Ac-GpYLPQTV-NH2 acetate is a STAT3 inhibitor with an IC50 value of 0.33 μM. It exhibits antitumor activity and is intended for research use only.
- STAT3 inhibitor (IC50: 0.33 μM)
- Exhibits antitumor activity
- White to off-white solid appearance
- Soluble in DMSO (100 mg/mL)
- Storage as powder: -80°C for 2 years, -20°C for 1 year (sealed, away from moisture)
- Storage in solvent: -80°C for 6 months, -20°C for 1 month (sealed, away from moisture)
Medchemexpress LLC Leachianone A | 97938-31-3 | 1 ML
Leachianone A, isolated from Radix Sophorae, demonstrates anti-malarial, anti-inflammatory, and cytotoxic properties. It induces apoptosis through both extrinsic and intrinsic pathways.
- Induces apoptosis via both extrinsic and intrinsic pathways.
- Exhibits marked inhibition on the survival of HepG2 cells.
- Decreases the precursor of caspase-3.
- Reduces protein levels of pro-forms of upstream initiator caspases.
- Significantly diminishes tumor volume in animal models.
- Soluble in DMSO at 100 mg/mL.
Chemscene Sodium naphthalene-1-sulfonate | 100g | CS-W014185 | 80% | 130-14-3 | MFCD00064964 | 230 22 | C10H7NaO3S
Chemscene | Sodium naphthalene-1-sulfonate | 100g | CS-W014185 | 80% | 130-14-3 | MFCD00064964 | 230 22 | C10H7NaO3S
Chemscene Veratraldehyde | 100g | CS-W019906 | 98% | 120-14-9 | MFCD00003363 | 166 18 | C9H10O3
Chemscene | Veratraldehyde | 100g | CS-W019906 | 98% | 120-14-9 | MFCD00003363 | 166 18 | C9H10O3
Medchemexpress LLC Concanavalin A (fluorescein) | 2ML
Concanavalin A (Fluorescein) is a biological material or organic compound that appears as a colorless to light yellow liquid. This compound is intended for use in life science research.
- Used in life science research
- Appears as a colorless to light yellow liquid
Chemscene 1-Bromo-4-chlorobenzene | 500g | CS-0015927 | 98% | 106-39-8 | MFCD00000600 | 191 46 | C6H4BrCl
Chemscene | 1-Bromo-4-chlorobenzene | 500g | CS-0015927 | 98% | 106-39-8 | MFCD00000600 | 191 46 | C6H4BrCl
C(=O)N[C@@H](C)C(=O)Nc1ccc(CO)cc1 | 10g | 808882346](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471206.jpg-250.jpg)
eMolecules 1343476-44-7 | (S)-2-Amino-N-((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)-3-methylbutanamide | Combi-Blocks, Inc.293.367 | C15H23N3O3 | 95.000 | CC(C)[C@H](N)C(=O)N[C@@H](C)C(=O)Nc1ccc(CO)cc1 | 10g | 808882346
(S)-2-Amino-N-((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)-3-methylbutanamide | Combi-Blocks, Inc. | 1343476-44-7293.367 | C15H23N3O3 | 95.000 | CC(C)[C@H](N)C(=O)N[C@@H](C)C(=O)Nc1ccc(CO)cc1 | 10g | 808882346
eMolecules 1260897-05-9 | 3,3-Difluorocyclopentanecarboxylic acid | Combi-Blocks, Inc. | MFCD15526661 | 150.125 | C6H8F2O2 | 96.000 | OC(=O)C1CCC(F)(F)C1 | 25g | 866384251
3,3-Difluorocyclopentanecarboxylic acid | Combi-Blocks, Inc. | 1260897-05-9 | MFCD15526661 | 150.125 | C6H8F2O2 | 96.000 | OC(=O)C1CCC(F)(F)C1 | 25g | 866384251
eMolecules 107496-54-8 | 3,3-Difluorocyclobutanecarboxylic acid | AA Blocks LLC | MFCD08705857 | 136.098 | C5H6F2O2 | 0.000 | OC(=O)C1CC(F)(F)C1 | 25g | 410191797
3,3-Difluorocyclobutanecarboxylic acid | AA Blocks LLC | 107496-54-8 | MFCD08705857 | 136.098 | C5H6F2O2 | 0.000 | OC(=O)C1CC(F)(F)C1 | 25g | 410191797
Chemscene 2-Methoxyisonicotinic acid | 5g | CS-D0186 | 98% | 105596-63-2 | MFCD04115718 | 153 14 | C7H7NO3
Chemscene | 2-Methoxyisonicotinic acid | 5g | CS-D0186 | 98% | 105596-63-2 | MFCD04115718 | 153 14 | C7H7NO3
eMolecules 126705-22-4 | 1-(Fmoc-amino)cyclopropanecarboxylic acid | Acrotein ChemBio Inc. | MFCD00190873 | 323.348 | C19H17NO4 | 97.000 | OC(=O)C1(CC1)NC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 487521681
1-(Fmoc-amino)cyclopropanecarboxylic acid | Acrotein ChemBio Inc. | 126705-22-4 | MFCD00190873 | 323.348 | C19H17NO4 | 97.000 | OC(=O)C1(CC1)NC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 487521681