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Organic compounds that consist of a benzene ring substituted with amino and carboxyl groups. Includes compounds that are derived from aminobenzoic acids.
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Amino-PEG16-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are molecules that utilize a linker to connect two ligands: one for an E3 ubiquitin ligase and another for a target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
PEG-based linker for PROTAC synthesis.
Enables selective degradation of target proteins.
Utilizes the intracellular ubiquitin-proteasome system.
Solid appearance, white to off-white color.
For research use only.
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Amino-PEG16-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein.
PEG-based PROTAC linker
Used for PROTAC synthesis
Exploits intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Amino-PEG16-acid is a PEG-based PROTAC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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M-PEG16-COOH is a PEG-based PROTAC linker. It is designed for use in the synthesis of PROTACs, which are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Can be used in the synthesis of PROTACs
Exploits the ubiquitin-proteasome system
Selectively degrades target proteins
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Amino-PEG16-acid is an amine-terminated polyethylene glycol (PEG16) linker designed for use in the chemical synthesis of proteolysis targeting chimeras (PROTACs) and other bifunctional conjugates. It provides a hydrophilic, flexible spacer with reactive termini suitable for orthogonal coupling strategies and is supplied as a research-grade reagent with a reported purity of 95%.
Amine-terminated PEG16 linker useful for PROTAC synthesis.
Hydrophilic and flexible spacer to improve solubility and reduce steric hindrance.
Terminal carboxylic acid and primary amine for orthogonal conjugation chemistries.
Reported purity 95.0% suitable for research applications.
Molecular weight ~793.93 Da; formula C35H71NO18.
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