Aminobenzoic acids and derivatives
Medchemexpress LLC YSK 05 | 1318793-78-0 | 98.68% | 628.07 | 1 ML
YSK 05 is a pH-sensitive cationic lipid that enhances the intracellular trafficking of non-viral vectors. It is notable for its ability to overcome the suppression of endosomal escape caused by PEGylation and effectively enhances siRNA delivery both in vitro and in vivo. YSK 05 facilitates the endosomal escape of MEND, thereby improving the efficacy of siRNA delivery into the cytosol and enhancing gene silencing.
- Enhances intracellular trafficking of non-viral vectors
- Exhibits significant gene silencing activity and hemolytic activity
- Overcomes suppression of endosomal escape by PEGylation
- Effective in enhancing siRNA delivery both in vitro and in vivo
- Used for research purposes in areas like oligonucleotides, cationic lipids, and drug delivery
- Related to cancer research, including cancer metabolism and metastasis
Chemscene TSTU | 500g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Chemscene | TSTU | 500g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Chemscene TSTU | 10g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Chemscene | TSTU | 10g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Chemscene TSTU | 25g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Chemscene | TSTU | 25g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Chemscene TSTU | 100g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Chemscene | TSTU | 100g | CS-W012128 | 98% | 105832-38-0 | MFCD00077875 | 301 05 | C9H16BF4N3O3
Medchemexpress LLC Pomalidomide-amino-PEG5-NH2 hydrochloride | 2421217-05-0 | MFCD01304495 | 99.6% | C25H35ClN4O10 | 10MG
Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate combining a pomalidomide-derived cereblon ligand with a PEG5 amine linker. Supplied as the hydrochloride salt, it is intended as a research building block for proteolysis targeting chimera (PROTAC) design and ligand-linker conjugation studies.
- Suitable for PROTAC synthesis and E3 ligase targeting.
- Hydrochloride salt improves handling and stability.
- High purity appropriate for research applications.
- Soluble in DMSO at high concentration; ultrasonic assistance recommended.
- Stable when stored sealed at 4°C; defined solvent storage conditions extend shelf life.
- Supplied as a solid for convenient weighing and storage.
Chemscene 5-Bromoindole | 500g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene | 5-Bromoindole | 500g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene 5-Bromoindole | 10g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene | 5-Bromoindole | 10g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene 5-Bromoindole | 25g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene | 5-Bromoindole | 25g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene 5-Bromoindole | 100g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene | 5-Bromoindole | 100g | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene 5-Bromoindole | 1kg | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Chemscene | 5-Bromoindole | 1kg | CS-D0617 | 98% | 10075-50-0 | MFCD00005670 | 196 05 | C8H6BrN
Selleck Chemical LLC ESI-05 S3382-5mg
ESI-05 (NSC 116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist with IC50 of 0 4 M ESI-05 (NSC 116966) inhibits cAMP-mediated activation of EPAC2 and EAPC2 mediated Rap1 activation
Selleck Chemical LLC ESI-05 S3382-25mg
ESI-05 (NSC 116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist with IC50 of 0 4 M ESI-05 (NSC 116966) inhibits cAMP-mediated activation of EPAC2 and EAPC2 mediated Rap1 activation
Apexbio Technology LLC Bromocriptine mesylate 22260-51-1 10mM (in 1mL DMSO)
Bromocriptine mesylate (CAS 22260-51-1) is a selective agonist of D -like dopamine receptors exhibiting high affinity with a pKi of 8 05 0 2 Through modulation of D receptor activity bromocriptine mesylate influences metabolic processes by reducing glucose intolerance and insulin resistance inhibits pituitary prolactin secretion and enhances motor function relevant to Parkinson s disease The compound has established applications in research on metabolic disorders neuroendocrine regulation and neurodegenerative diseases including studies pertaining to type 2 diabetes prolactinomas acromegaly and Parkinson s disease
Apexbio Technology LLC Bromocriptine mesylate 22260-51-1 50mg
Bromocriptine mesylate (CAS 22260-51-1) is a selective agonist of D -like dopamine receptors exhibiting high affinity with a pKi of 8 05 0 2 Through modulation of D receptor activity bromocriptine mesylate influences metabolic processes by reducing glucose intolerance and insulin resistance inhibits pituitary prolactin secretion and enhances motor function relevant to Parkinson s disease The compound has established applications in research on metabolic disorders neuroendocrine regulation and neurodegenerative diseases including studies pertaining to type 2 diabetes prolactinomas acromegaly and Parkinson s disease