Benzenesulfonamides
Medchemexpress LLC HY-110195 10mg Medchemexpress, Smurf1-IN-A01 CAS:1007647-73-5 Purity:>98%
Medchemexpress, HY-110195 10mg Smurf1-IN-A01 CAS:1007647-73-5 Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 g/mol | C17H22N2O5S2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248736.png-250.jpg)
Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 g/mol | C17H22N2O5S2 | 100 MG
TMI-1 (WAY-171318) is a small-molecule inhibitor of TNF-α converting enzyme (TACE) with reported activity against ADAM-17, ADAMTS-4, and multiple MMPs. Supplied for research use, it has demonstrated oral activity and induces apoptosis in cancer cell models, and is provided with analytical documentation for laboratory studies.
- Purity 99.57%.
- Molecular formula C17H22N2O5S2.
- Molecular weight 398.50 g/mol.
- Available as solid (5 mg, 10 mg, 25 mg, 50 mg, 100 mg) and solution (10 mM in DMSO).
- Includes datasheet, COA, and SDS documentation.
- Suitable for biochemical, cell-based, and in vivo oral dosing research (research use only).
![Medchemexpress LLC 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- | 2160546-07-4 | 100.0% | 377.27 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000364203-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- | 2160546-07-4 | 100.0% | 377.27 | 5 MG
IACS-13909 is a selective, potent, and orally active SHP2 allosteric inhibitor. It exhibits greater selectivity for SHP2 over other phosphatases, including SHP1. This compound demonstrates antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinase (RTK)-dependent cancers.
- Potently suppresses the proliferation of wild-type SHP2 and KYSE-520 cells.
- Suppresses pERK and pMEK levels in wild-type SHP2 and KYSE-520 cells.
- Inhibits the proliferation of parental cells and NCI-H1975 CS cells in a dose-dependent manner.
- Achieved 100% tumor growth inhibition (TGI) in mice studies.
- Functions as a selective SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM.
Medchemexpress LLC N-desmethyl sildenafil-d8 | 1185168-06-2 | MFCD11977920 | 99.3% | 468.60 g/mol | C21H20D8N6O4S | 5 MG
N-Desmethyl sildenafil-d8 is a deuterium-labeled analytical standard of the N-desmethyl metabolite of sildenafil, provided in milligram quantities for research and quantitative analysis. It is intended for use as an internal standard in mass-spectrometry, pharmacokinetic, and metabolic studies, and is supplied with recommended storage conditions to preserve isotopic integrity.
- Deuterium-labeled internal standard for quantitative LC-MS/MS analysis.
- High purity suitable for analytical and pharmacokinetic studies.
- Supplied in small milligram amounts for precise measurements.
- Stable under recommended storage to maintain isotopic composition.
- Appropriate as a reference material for metabolite identification.
Sigma Aldrich Fine Chemicals Biosciences Glibenclamide impurity A European Pharmacopoeia (EP) Reference Standard | 16673-34-0 | MFCD00193756 |
Glibenclamide impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 368.84 | 16673-34-0 | MFCD00193756 |
eMolecules 486422-57-5 | 4-(Pyrrolidinylsulfonyl)phenylboronic acid | Combi-Blocks | MFCD06659847 | 255.100 | C10H14BNO4S | 98.000 | OB(O)c1ccc(cc1)S(=O)(=O)N1CCCC1 | 1g | 117521167
4-(Pyrrolidinylsulfonyl)phenylboronic acid | Combi-Blocks | 486422-57-5 | MFCD06659847 | 255.100 | C10H14BNO4S | 98.000 | OB(O)c1ccc(cc1)S(=O)(=O)N1CCCC1 | 1g | 117521167
eMolecules 658084-23-2 | Medchem Express | SU11274 | 5mg | 673358807 | HY-12014 | 568.09 | C28H30ClN5O4S
Medchem Express | SU11274 | 5mg | 673358807 | HY-12014 | 658084-23-2 | 568.090 | C28H30ClN5O4S
eMolecules 2922283-37-0 | Medchem Express | SG-094 | 5mg | 783660551 | HY-148816 | 451.566 | C30H29NO3
ChemScene | 3-Amino-4-bromobenzonitrile | 100mg | 536788564 | CS-0042785 | 72635-78-0 | MFCD11036380 | 197.035 | C7H5BrN2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
eMolecules 701-34-8 | 4-Bromobenzenesulfonamide | ChemScene | MFCD00051977 | 236.080 | C6H6BrNO2S | 98.000 | NS(=O)(=O)c1ccc(Br)cc1 | 10g | 894453058
4-Bromobenzenesulfonamide | ChemScene | 701-34-8 | MFCD00051977 | 236.080 | C6H6BrNO2S | 98.000 | NS(=O)(=O)c1ccc(Br)cc1 | 10g | 894453058
Aobchem 2-(Methylthio)-1-phenyl-1H-imidazole | 95% | CAS 40279-09-2 | C10H10N2S | 1g
2-(Methylthio)-1-phenyl-1H-imidazole | 95% | CAS 40279-09-2 | C10H10N2S | 1g
Chemscene ChemScene | Piloty's acid | 10G | CS-0079805 | 0.97 | 599-71-3| MFCD00025013 | 173.19
ChemScene | Piloty's acid | 10G | CS-0079805 | 0.97 | 599-71-3| MFCD00025013 | 173.19
Medchemexpress LLC HY-15724 5mg Medchemexpress, Vercirnon CAS:698394-73-9 Purity:>98%
Medchemexpress, HY-15724 5mg Vercirnon CAS:698394-73-9 Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.