Benzenesulfonamides
eMolecules 1532593-30-8 | Medchem Express | ML355 | 5mg | 446261079 | HY-12341 | MFCD28167822 | 441.52 | C21H19N3O4S2
Ambeed | 3-(Thiophen-2-yl)pyridine | 100mg | 642081265 | A794117 | 21298-53-3 | MFCD01860052 | 161.220 | C9H7NS
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![Medchemexpress LLC Benzeneacetamide, 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulf) | 439288-66-1 | 99.95% | 544.62 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000393827.png-250.jpg)
Medchemexpress LLC Benzeneacetamide, 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulf) | 439288-66-1 | 99.95% | 544.62 | 100 MG
Benzeneacetamide, 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulf) | 439288-66-1 | 99.95% | 544.62 | 100 MG
Medchemexpress LLC Furosemide (standard) | 54-31-9 | 99.9% | 100 MG
Furosemide (Standard) is an analytical reference standard for research and analytical applications. It acts as a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, specifically NKCC1 and NKCC2, and also functions as a GABAA receptor antagonist. This compound is used in the study of congestive heart failure, hypertension, and edema, and is commonly employed in qualitative, quantitative, and methodological research experiments like HPLC, GC, and MS.
- Potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter
- Functions as a GABAA receptor antagonist
- Exhibits 100-fold selectivity for α6-containing receptors over α1-containing receptors
- Acts as a loop diuretic
- Utilized in the study of congestive heart failure, hypertension, and edema
- Analytical standard grade
- Suitable for qualitative, quantitative, and methodological research experiments
Medchemexpress LLC Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]- | 54-31-9 | 99.8% | 5 G
Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. It also acts as a GABAA receptor antagonist, displaying 100-fold selectivity for α6-containing receptors over α1-containing receptors. It functions as a loop diuretic and is used in studies of congestive heart failure, hypertension, and edema.
- Potent and orally active inhibitor of NKCC cotransporter
- Antagonist of GABAA receptors with high selectivity for α6-containing receptors
- Functions as a loop diuretic
- Used for the study of congestive heart failure, hypertension, and edema
- Targets NKCC and GABA receptor
- Pathway involves membrane transporter/ion channel and neuronal signaling
Selleck Chemical LLC EG00229-E1119-5MG
EG00229 is a neuropilin 1 (NRP1) receptor antagonist with an IC50 of 3 M against VEGF-A binding to NRP1 b1 domain
![eMolecules 36982-84-0 | 2,4,6-Triisopropylbenzenesulfonyl azide | Chem-Impex | MFCD00859286 | 309.430 | C15H23N3O2S | 99.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N=[N+]=[N-] | 25g | 112748840](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501715615.jpg-250.jpg)
eMolecules 36982-84-0 | 2,4,6-Triisopropylbenzenesulfonyl azide | Chem-Impex | MFCD00859286 | 309.430 | C15H23N3O2S | 99.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N=[N+]=[N-] | 25g | 112748840
2,4,6-Triisopropylbenzenesulfonyl azide | Chem-Impex | 36982-84-0 | MFCD00859286 | 309.430 | C15H23N3O2S | 99.000 | CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N=[N+]=[N-] | 25g | 112748840
eMolecules 873-41-6 | 3,5,6-Trichloro-1,2,4-triazine | AA Blocks LLC | MFCD09033774 | 184.400 | C3Cl3N3 | 0.000 | Clc1nnc(Cl)c(Cl)n1 | 10g | 571778022
3,5,6-Trichloro-1,2,4-triazine | AA Blocks LLC | 873-41-6 | MFCD09033774 | 184.400 | C3Cl3N3 | 0.000 | Clc1nnc(Cl)c(Cl)n1 | 10g | 571778022
eMolecules 773-64-8 | 2-Mesitylenesulfonyl chloride | ChemScene | MFCD00007434 | 218.700 | C9H11ClO2S | 98.000 | Cc1cc(C)c(c(C)c1)S(Cl)(=O)=O | 25g | 794524869
2-Mesitylenesulfonyl chloride | ChemScene | 773-64-8 | MFCD00007434 | 218.700 | C9H11ClO2S | 98.000 | Cc1cc(C)c(c(C)c1)S(Cl)(=O)=O | 25g | 794524869
Medchemexpress LLC YAP-TEAD-IN-1 TFA | 1659305-79-9 | 99.99% | 2133.88 | 5 MG
YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction, demonstrating an IC50 of 25 nM. This 17mer peptide is characterized by its higher binding affinity to TEAD1 (Kd=15 nM) compared to YAP (50-171) (Kd= 40 nM). It functions by inhibiting the interaction between YAP and TEAD, key proteins involved in cell proliferation and organ size regulation.
- Potent and competitive peptide inhibitor
- Inhibits YAP-TEAD interaction with an IC50 of 25 nM
- 17mer peptide structure
- Higher binding affinity to TEAD1 (Kd=15 nM) than to YAP (50-171) (Kd= 40 nM)
- Impacts cell proliferation and organ size regulation
eMolecules 41733-55-5 | Medchem Express | Furosemide (sodium) | 500mg | 491484379 | HY-B0135A | MFCD23379919 | 352.72 | C12H10ClN2NaO5S
Ambeed | 3-Hydroxy-N-phenyl-2-naphthamide | 25g | 628567401 | A293708 | 92-77-3 | MFCD00004096 | 263.296 | C17H13NO2
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Medchemexpress LLC Sulfacetamide (Standard) | 144-80-9 | 250 MG
Sulfacetamide (Standard) | 144-80-9 | 250 MG
Selleck Chemical LLC IQ-1S
IQ-1S is a JNK3 inhibitor with Kd values of 87 360 and 390 nM for JNK3 JNK2 and JNK1 respectively
Medchemexpress LLC GW806742X hydrochloride | 98.3% | 610.01 | 10 MG
GW806742X hydrochloride is an ATP mimetic and a potent inhibitor of MLKL (Mixed Lineage Kinase Domain-Like protein), binding to its pseudokinase domain with a Kd of 9.3 μM. It also shows activity against VEGFR2 with an IC50 of 2 nM. This compound effectively retards MLKL membrane translocation and inhibits necroptosis.
- Potent MLKL inhibitor (Kd = 9.3 μM)
- Activity against VEGFR2 (IC50 = 2 nM)
- Retards MLKL membrane translocation
- Inhibits necroptosis
- Inhibits necroptotic death of wild-type mouse dermal fibroblasts in a dose-dependent manner
- Inhibits VEGF induced proliferation of HUVECs with an IC50 of 5 nM
eMolecules 701-34-8 | 4-Bromobenzenesulfonamide | ChemScene | MFCD00051977 | 236.080 | C6H6BrNO2S | 98.000 | NS(=O)(=O)c1ccc(Br)cc1 | 5g | 866871961
4-Bromobenzenesulfonamide | ChemScene | 701-34-8 | MFCD00051977 | 236.080 | C6H6BrNO2S | 98.000 | NS(=O)(=O)c1ccc(Br)cc1 | 5g | 866871961