Benzenesulfonamides
Medchemexpress LLC N-desmethyl sildenafil | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 | C21H28N6O4S | 25 MG
N-desmethyl sildenafil is the primary N-desmethylated metabolite of sildenafil supplied as an analytical reference standard for laboratory research. It is available in solid and solution formats for analytical applications and quality control, and is intended for research use only (not for human or clinical use).
- Provided as solid and solution formats for flexibility in assays.
- High purity (99.5%) suitable for analytical and reference standard use.
- Molecular formula C21H28N6O4S; molecular weight 460.55.
- Used in pharmacokinetic, metabolite identification, and analytical method development studies.
- Available in multiple small-scale pack sizes for laboratory workflows.
Medchemexpress LLC HY-112438 5mg Medchemexpress, MF-094 CAS:2241025-68-1 Purity:>98%
Medchemexpress, HY-112438 5mg MF-094 CAS:2241025-68-1 MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Sildenafil Inhibitors
A PDE5 inhibitor (IC50s = 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively); selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 μM, respectively); reverses glucose-induced decreases in ANG1 expression and reduction of capillary-like tube formation by mouse dermal endothelial cells in vitro; increases the number of functional blood vessels and regional blood flow in the sciatic nerve in a db/db mouse model of diabetic peripheral neuropathy; increases ICP/MAP ratio in castrated rats at 20 mg/kg per day; reduces cardiac arrest and resuscitation-induced increases in angiotensin II ACE, ACE2, and various angiotensin receptors and increases survival in a porcine model of ischemia/reperfusion injury
eMolecules 97-04-1 | ChemScene | 2-Chloro-5-sulfamoylbenzoic acid | 100mg | 761228608 | CS-0462903 | MFCD00036103 | 235.64 | C7H6ClNO4S
ChemScene | 2-Chloro-5-sulfamoylbenzoic acid | 100mg | 761228608 | CS-0462903 | 97-04-1 | MFCD00036103 | 235.640 | C7H6ClNO4S
AdipoGen Glimepiride (1 g)
Chemical. CAS: 93479-97-1. Formula: C24H34N4O5S. MW: 490.62. Glimepiride is a long-acting sulfonylurea antidiabetic agent inhibiting ATP-sensitive potassium (KATP) channels in pancreatic beta-cells, which leads to the release of insulin. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase and stimulates glucose transporter 1 and 4 (GLUT1/4) expression. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway and exhibits neuroprotective benefit, decreasing expression and activity of BACE1 and amyloid-beta (Abeta) in neurons in a PPARgamma-dependent manner.
Frontier Specialty Chemicals 5G 4-BROMO-N,N-DIMETHYLBENZENE
4-Bromo-N,N-dimethylbenzenesulfonamide; CAS No: 707-60-8
Medchemexpress LLC HY-16586 10mg Medchemexpress, PFI-1 CAS:1403764-72-6 Purity:>98%
Medchemexpress, HY-16586 10mg PFI-1 CAS:1403764-72-6 PFI-1 is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 701-34-8 | 4-Bromobenzenesulfonamide | Oakwood Chemical | MFCD00051977 | 236.080 | C6H6BrNO2S | 95.000 | NS(=O)(=O)c1ccc(Br)cc1 | 1g | 537717804
4-Bromobenzenesulfonamide | Oakwood Chemical | 701-34-8 | MFCD00051977 | 236.080 | C6H6BrNO2S | 95.000 | NS(=O)(=O)c1ccc(Br)cc1 | 1g | 537717804
eMolecules 99584-48-2 | 3,6-DICHLORO-1,2,4-TRIAZINE | AstaTech149.960 | C3HCl2N3 | 95.000 | Clc1cnc(Cl)nn1 | 0.25g | 718078673
3,6-DICHLORO-1,2,4-TRIAZINE | AstaTech | 99584-48-2149.960 | C3HCl2N3 | 95.000 | Clc1cnc(Cl)nn1 | 0.25g | 718078673
eMolecules 773-64-8 | 2-Mesitylenesulfonyl chloride | Ambeed | MFCD00007434 | 218.700 | C9H11ClO2S | 95.000 | Cc1cc(C)c(c(C)c1)S(Cl)(=O)=O | 25g | 552746994
2-Mesitylenesulfonyl chloride | Ambeed | 773-64-8 | MFCD00007434 | 218.700 | C9H11ClO2S | 95.000 | Cc1cc(C)c(c(C)c1)S(Cl)(=O)=O | 25g | 552746994
Medchemexpress LLC Sulfacetamide (Standard) | 144-80-9 | 250 MG
Sulfacetamide (Standard) | 144-80-9 | 250 MG
Medchemexpress LLC Desmorpholinyl navitoclax-NH-Me | 2365172-82-1 | MFCD32857149 | 98.6% | 918.55 | C44H51ClF3N5O5S3 | 5 MG
Desmorpholinyl Navitoclax-NH-Me is a navitoclax-derived BCL-XL inhibitor provided as a purified research chemical and synthetic building block for medicinal chemistry and PROTAC development. It is supplied in multiple small-scale pack sizes for laboratory use and includes characterization data for research applications.
- High purity suitable for biochemical and medicinal research (reported 98.64%).
- Available in multiple small pack sizes for screening and synthesis work.
- Molecular weight 918.55 and defined molecular formula for accurate reagent selection.
- SMILES and structural data provided to support cheminformatics workflows.
- Applicable as a building block in PROTAC synthesis and BCL-XL targeted studies.
eMolecules 287403-39-8 | Medchem Express | TMI-1 | 5mg | 719836655 | HY-101448 | MFCD09027399 | 398.49 | C17H22N2O5S2
Ambeed | 3-Chloro-6-(methylsulfonyl)pyridazine | 1g | 588342586 | A416883 | 7145-62-2 | MFCD03931474 | 192.620 | C5H5ClN2O2S
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