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Organic compounds that consist of a phenol ring with a ciclohexane substitution; includes compounds in which the ciclohexane group has additional substitutions.
EW-7195 is a potent, selective ALK5 (TGFβR1) inhibitor for research use that blocks TGF-β1-induced Smad signaling, epithelial-to-mesenchymal transition, and metastatic progression in preclinical studies. It provides low-nanomolar potency and is supplied with high purity for laboratory assays.
Potent ALK5 inhibition with low-nanomolar IC50.
High selectivity over related kinases, >300-fold versus p38α.
Blocks TGF-β1-induced Smad signaling and epithelial-to-mesenchymal transition.
Demonstrated anti-metastasis activity in preclinical models.
High purity suitable for research applications.
Soluble in DMSO for assay preparation.
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ML-9 (free base) is a small-molecule kinase inhibitor used in biochemical and cell-based research to probe myosin light-chain kinase (MLCK) and Akt-related signaling. It also modulates PKA, PKC, and STIM1 activity and can induce autophagy, making it useful for studies of cytoskeleton regulation and autophagic processes.
Inhibits myosin light-chain kinase and Akt kinase.
Modulates PKA, PKC, and STIM1 activity.
Induces autophagy by promoting autophagosome formation.
Suitable for biochemical and cell-based assays.
Well characterized with reported chemical identifiers and molecular weight.
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2-Methyl-1,3-cyclohexanedione is a small-molecule organic compound used as a synthetic intermediate in pharmaceutical and specialty-chemical synthesis. It is supplied as a solid with high analytical purity for research and development and is reported for use in cosmetic ingredient applications.
High purity (≈99.9%).
Molecular formula C7H10O2.
Molecular weight 126.15 g/mol.
Solid form suitable for handling and storage.
Useful synthetic intermediate for drug and specialty-chemical synthesis.
Available in multiple laboratory pack sizes for research use.
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Olaquindox is a quinoxaline-derivative antibiotic supplied as a research-grade solid. It is orally active and has been used historically as a growth promoter in swine; provided at high purity for laboratory and analytical applications.
High purity (99.9%) suitable for analytical use.
Orally active quinoxaline derivative with documented biological effects.
Solid, light yellow to green-yellow appearance for easy handling.
Suitable for research and analytical applications.
Store protected from light at 4°C; in solvent, store at -80°C for long-term stability.
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Prudomestin is a flavonoid isolated from the heartwood of Prunus domestica that exhibits potent xanthine oxidase (XO) inhibitory activity (IC50 ≈ 6 μM). It is supplied as a light yellow to yellow solid for research use and should be protected from light during storage.
Potent xanthine oxidase inhibitor (IC50 ≈ 6 μM).
Molecular formula C17H14O7.
Molecular weight 330.29 g/mol.
CAS number 3443-28-5.
Purity 98.4%.
Appearance light yellow to yellow solid.
Storage recommendations: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
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