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Organic compounds that consist of a phenol ring with a ciclohexane substitution; includes compounds in which the ciclohexane group has additional substitutions.
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Medchemexpress, HY-B0672 500mg Estradiol valerianate CAS:979-32-8 Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy drugs. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Promestriene is a synthetic diethyl ether derivative of estradiol supplied as a solid research reagent. It functions as a locally active estrogen and is used in in vitro and analytical studies of estrogen receptor activity and vaginal atrophy. The material is accompanied by quality documentation for research use only.
High purity (~99.9%) analytical standard.
Molecular weight 328.49 g/mol and formula C22H32O2 for accurate calculations.
Available in small solid quantities, including 10 mg, suitable for lab-scale experiments.
Supplied with a datasheet and batch information for quality control.
Intended for research and analytical use; not for clinical or human use.
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Effusol is a natural phenolic constituent isolated from Juncus effusus with potent radical-scavenging antioxidant activity and reported neuroprotective effects. Supplied as a research-grade solid, the manufacturer provides solubility guidance and storage recommendations for experimental use.
Natural phenolic constituent from Juncus effusus.
Potent antioxidant activity against DPPH and ABTS radicals.
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L319 is an ionizable cationic lipidoid, primarily used for synthetic liposomes. It is intended for research purposes only. This compound presents as a colorless to light yellow liquid.
Ionizable cationic lipidoid
Used for synthetic liposomes
Colorless to light yellow liquid
Density of 0.954 g/cm³
Stable for up to 3 years at -20°C in pure form
Soluble in DMSO at 100 mg/mL
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EW-7195 is a potent, selective ALK5 (TGFβR1) inhibitor for research use that blocks TGF-β1-induced Smad signaling, epithelial-to-mesenchymal transition, and metastatic progression in preclinical studies. It provides low-nanomolar potency and is supplied with high purity for laboratory assays.
Potent ALK5 inhibition with low-nanomolar IC50.
High selectivity over related kinases, >300-fold versus p38α.
Blocks TGF-β1-induced Smad signaling and epithelial-to-mesenchymal transition.
Demonstrated anti-metastasis activity in preclinical models.
High purity suitable for research applications.
Soluble in DMSO for assay preparation.
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EW-7195 is a potent and selective ALK5 (TGFβR1) inhibitor with an IC50 of 4.83 nM. It exhibits over 300-fold selectivity for ALK5 over p38α. This inhibitor effectively blocks TGF-β1-induced Smad signaling, epithelial-to-mesenchymal transition (EMT), and breast tumor metastasis to the lung. It is intended for research use only.
Potent and selective ALK5 (TGFβR1) inhibitor
Inhibits TGF-β1-induced Smad signaling
Blocks epithelial-to-mesenchymal transition (EMT)
Reduces breast tumor metastasis to the lung
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AZD8848 is a selective toll-like receptor 7 (TLR7) anteagent agonist developed for asthma and allergic rhinitis research. It shows good activity against TLR7, with cellular pEC50s of 7.0 for human TLR7 and 6.6 for rat TLR7. It has an EC50 of 4 nM in the induction of IFNα from human PBMCs and an IC50 of 0.2-1.0 nM for the inhibition of IL-5. AZD8848 has no activity against human TLR8 or any other human TLRs. In vivo, it has a good pharmacokinetics in Brown Norway rats and suppresses ovalbumin (OVA) challenge in a rat allergy model.
Appearance: solid
Color: white to off-white
Shipping: room temperature in continental US; may vary elsewhere
Storage:
Powder: -20°C for 3 years, 4°C for 2 years
In solvent: -80°C for 6 months, -20°C for 1 month
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More