Cyclohexylphenols
Sigma Aldrich Fine Chemicals Biosciences Estriol European Pharmacopoeia (EP) Reference Standard | 50-27-1 | MFCD00003691 |
Estriol European Pharmacopoeia (EP) Reference Standard | Mol Wt: 288.38 | 50-27-1 | MFCD00003691 |
Medchemexpress LLC EZM0414 | 2411748-50-8 | 99.1% | C22H29FN4O2 | 50 MG
EZM0414 is a potent, selective, and orally bioavailable inhibitor of SETD2. It is used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma.
- Potent, selective, orally bioavailable inhibitor of SETD2
- IC50 of 18 nM in SETD2 biochemical assay
- IC50 of 34 nM in cellular assay
- Inhibits proliferation of MM and DLBCL cell lines
- Well-tolerated and inhibits tumor growth in xenograft models
- Almost 100% oral bioavailability in rats and mice
Medchemexpress LLC Estradiol-d4 | 66789-03-5 | 99.12% | 5 MG
Estradiol-d4 is the deuterium-labeled form of Estradiol. Estradiol is a steroid sex hormone crucial for maintaining fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway. This compound can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporated stable heavy isotopes for quantitation during drug development
- Deuteration may influence pharmacokinetic and metabolic profiles
- White to off-white solid
- Molecular weight of 276.41
- Chemical formula of C18H20D4O2
Medchemexpress LLC Cyanosafracin B | 96996-50-8 | 96.01% | 549.62 | 50 MG
Cyanosafracin B is a starting material for the synthesis of Ecteinascidin ET-743 and Phthalascidin Pt-650.
- It is a solid.
- It appears light yellow to yellow in color.
- It is sourced from microorganisms.
- It is a marine natural product.
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol (17ẞ)-, 3-benzoate | 50-50-0 | 99.9% | 500 MG
Estradiol benzoate (β-Estradiol 3-benzoate) is an HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription and replication. It also exhibits antifertility effects, anti-*Toxoplasma gondii* activity, and can improve memory behavior in Ovariectomy (Ovx) female mice.
- HBx protein inhibitor
- Inhibits androgen and hepatitis B virus (HBV) transcription and replication
- Shows antifertility effects
- Possesses anti-*Toxoplasma gondii* activity
- Can improve memory behavior of Ovariectomy (Ovx) female mice
Medchemexpress LLC EW-7195 | 1352609-28-9 | 98.84% | 406.44 | 50 MG
EW-7195 is a potent and selective ALK5 (TGFβR1) inhibitor with an IC50 of 4.83 nM. It exhibits over 300-fold selectivity for ALK5 over p38α. This inhibitor effectively blocks TGF-β1-induced Smad signaling, epithelial-to-mesenchymal transition (EMT), and breast tumor metastasis to the lung. It is intended for research use only.
- Potent and selective ALK5 (TGFβR1) inhibitor
- Inhibits TGF-β1-induced Smad signaling
- Blocks epithelial-to-mesenchymal transition (EMT)
- Reduces breast tumor metastasis to the lung
eMolecules ChemScene / 1-(2-Methoxyphenyl)ethanamine hydrochloride / 100mg / 603128754 / CS-0158118 / 0.000 / 17087-50-2 / MFCD02675834 / 187.670 / C9H14ClNO
ChemScene / 1-(2-Methoxyphenyl)ethanamine hydrochloride / 100mg / 603128754 / CS-0158118 / 0.000 / 17087-50-2 / MFCD02675834 / 187.670 / C9H14ClNO
Medchemexpress LLC Au-15330 | 2380274-50-8 | 99.9% | C39H49N9O5S | 50 MG
AU-15330 is a proteolysis-targeting chimera (PROTAC) degrader of the SWI/SNF ATPase subunits, SMARCA2 and SMARCA4. It potently inhibits tumor growth in xenograft models of prostate cancer and works synergistically with the AR antagonist enzalutamide. It also induces disease remission in castration-resistant prostate cancer (CRPC) models without causing toxicity.
- Effectively inhibits tumor growth in xenograft models
- Works synergistically with enzalutamide
- Induces disease remission in CRPC models
- Does not cause toxicity
![eMolecules Ambeed / (3aS3aS8aR8aR)-22-(23-Dihydro-1H-indene-22-diyl)bis(3a8a-dihydro-8H-indeno[12-d]oxazole) / 100mg / 627733116 / A1177861 / / 188780-28-1 / [null] / 432.523 / C29H24N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502447310.PNG-250.jpg)
eMolecules Ambeed / (3aS3aS8aR8aR)-22-(23-Dihydro-1H-indene-22-diyl)bis(3a8a-dihydro-8H-indeno[12-d]oxazole) / 100mg / 627733116 / A1177861 / / 188780-28-1 / [null] / 432.523 / C29H24N2O2
Ambeed / (3aS3aS8aR8aR)-22-(23-Dihydro-1H-indene-22-diyl)bis(3a8a-dihydro-8H-indeno[12-d]oxazole) / 100mg / 627733116 / A1177861 / / 188780-28-1 / [null] / 432.523 / C29H24N2O2
Medchemexpress LLC Fraxinol | 486-28-2 | 5 MG
Fraxinol is a compound isolated from *Lobelia chinensis* that acts as a Cytochrome P450 Inhibitor. It exhibits cytotoxicity against human U937 cells with a CC50 > 2 mM and growth inhibition with an IC50 > 400 μM after 48 hours.
- Isolated from Lobelia chinensis
- Identified as a Cytochrome P450 inhibitor
- High purity of 98.82%
- Cytotoxicity against human U937 cells (CC50 > 2 mM)
- Growth inhibition of human U937 cells (IC50 > 400 μM)
- Molecular formula: C11H10O5
- Molecular weight: 222.19
- Appearance: Light yellow to yellow solid
- Recommended storage: 4°C, sealed, away from moisture and light
Medchemexpress LLC Estriol | 50-27-1 | 500 MG
Estriol (Oestriol) is an orally active estrogen and an ERα and ERβ agonist. It is also a potent GPR30 antagonist in estrogen receptor-negative breast cancer cells. Estriol can ameliorate disease severity through immunomodulatory mechanisms that decrease tissue inflammation and has powerful proconvulsant effects.
- Orally active estrogen
- ERα and ERβ agonist
- Potent GPR30 antagonist in estrogen receptor-negative breast cancer cells
- Ameliorates disease severity through immunomodulatory mechanisms that decrease tissue inflammation
- Has powerful proconvulsant effects
Medchemexpress LLC ML-9 (free base) | 110448-31-2 | 99.9% | 324.83 | C15H17ClN2O2S | 50 MG
ML-9 (free base) is a small-molecule kinase inhibitor used in biochemical and cell-based research to probe myosin light-chain kinase (MLCK) and Akt-related signaling. It also modulates PKA, PKC, and STIM1 activity and can induce autophagy, making it useful for studies of cytoskeleton regulation and autophagic processes.
- Inhibits myosin light-chain kinase and Akt kinase.
- Modulates PKA, PKC, and STIM1 activity.
- Induces autophagy by promoting autophagosome formation.
- Suitable for biochemical and cell-based assays.
- Well characterized with reported chemical identifiers and molecular weight.