Cyclohexylphenols
Apexbio Technology LLC Estriol 50-27-1 100mg
Estriol (50-27-1) is a small-molecule estrogen receptor modulator targeting the G-protein coupled estrogen receptor (GPER) It is designed to antagonize GPER-dependent estrogen signaling thereby regulating estrogen-mediated cellular pathways independent of classical nuclear receptors Estriol exerts its biological activity primarily through antagonistic interaction with GPER In cell-based studies estriol demonstrates receptor-selective antagonistic activity in estrogen receptor-negative breast cancer cell lines Based on these pharmacological properties estriol holds research potential in oncology investigations involving hormone receptor-negative breast cancer and in the study of estrogen receptor-independent signaling pathways
Medchemexpress LLC Estriol | 50-27-1 | 500 MG
Estriol (Oestriol) is an orally active estrogen and an ERα and ERβ agonist. It is also a potent GPR30 antagonist in estrogen receptor-negative breast cancer cells. Estriol can ameliorate disease severity through immunomodulatory mechanisms that decrease tissue inflammation and has powerful proconvulsant effects.
- Orally active estrogen
- ERα and ERβ agonist
- Potent GPR30 antagonist in estrogen receptor-negative breast cancer cells
- Ameliorates disease severity through immunomodulatory mechanisms that decrease tissue inflammation
- Has powerful proconvulsant effects
Sigma Aldrich Fine Chemicals Biosciences Estriol European Pharmacopoeia (EP) Reference Standard | 50-27-1 | MFCD00003691 |
Estriol European Pharmacopoeia (EP) Reference Standard | Mol Wt: 288.38 | 50-27-1 | MFCD00003691 |
eMolecules Medchem Express / Estriol / 100mg / 446272675 / HY-B0412 / / 50-27-1 / MFCD00003691 / 288.387 / C18H24O3
Medchem Express / Estriol / 100mg / 446272675 / HY-B0412 / / 50-27-1 / MFCD00003691 / 288.387 / C18H24O3
eMolecules ChemScene / 11-Dicyclopropylethan-1-ol / 100mg / 686103506 / CS-0245445 / 0.000 / 18895-50-6 / MFCD01877353 / 126.199 / C8H14O
ChemScene / 11-Dicyclopropylethan-1-ol / 100mg / 686103506 / CS-0245445 / 0.000 / 18895-50-6 / MFCD01877353 / 126.199 / C8H14O
eMolecules ChemScene / 1-(2-Methoxyphenyl)ethanamine hydrochloride / 100mg / 603128754 / CS-0158118 / 0.000 / 17087-50-2 / MFCD02675834 / 187.670 / C9H14ClNO
ChemScene / 1-(2-Methoxyphenyl)ethanamine hydrochloride / 100mg / 603128754 / CS-0158118 / 0.000 / 17087-50-2 / MFCD02675834 / 187.670 / C9H14ClNO
Medchemexpress LLC 2-methyl-1,3-cyclohexanedione | 1193-55-1 | MFCD00001587 | 99.9% | 126.15 g/mol | C7H10O2 | 50 G
2-Methyl-1,3-cyclohexanedione is a small-molecule organic compound used as a synthetic intermediate in pharmaceutical and specialty-chemical synthesis. It is supplied as a solid with high analytical purity for research and development and is reported for use in cosmetic ingredient applications.
- High purity (≈99.9%).
- Molecular formula C7H10O2.
- Molecular weight 126.15 g/mol.
- Solid form suitable for handling and storage.
- Useful synthetic intermediate for drug and specialty-chemical synthesis.
- Available in multiple laboratory pack sizes for research use.
Medchemexpress LLC Aapk-25 | 2247919-28-2 | 98.1% | 442.32 | C21H13Cl2N3O2S | 50MG
AAPK-25 is a small-molecule dual inhibitor of Aurora kinases and Polo-like kinases (PLK) that induces mitotic delay and prometaphase arrest, making it useful for cell-based and biochemical studies of mitosis and kinase signaling. Supplied as an off-white to light-yellow solid with high reported purity and available in a 50 mg quantity.
- Dual Aurora and PLK inhibition providing mechanistic relevance for mitotic studies.
- Demonstrated anti-tumor activity in preclinical assays.
- High reported purity (98.09%).
- Available as a 50 mg solid for laboratory experiments.
- Soluble in DMSO; ultrasonication may be required for complete dissolution.
- Stock solutions stable at -80°C for up to 6 months and at -20°C for up to 1 month when protected from light.
Medchemexpress LLC AAPK-25 | 2247919-28-2 | 98.1% | 442.32 | C21H13Cl2N3O2S | 10MG
AAPK-25 is a small-molecule research compound that acts as a dual inhibitor of Aurora kinases (Aurora-A, -B, -C) and Polo-like kinases (PLK-1, -2, -3). It exhibits antiproliferative activity in several cancer cell lines and is supplied as an off-white to light yellow solid for in vitro use. Solubility in DMSO is 50 mg/mL, and recommended storage is 4°C with protection from light.
- Dual inhibition of Aurora and PLK kinases demonstrated by low nanomolar Kd values.
- Exhibits antiproliferative activity across multiple cancer cell lines.
- High purity suitable for in vitro biochemical and cellular assays.
- Available in multiple solid package sizes to support different study scales.
- Readily soluble in DMSO for assay formulation.
- Defined storage and in-solvent stability for consistent results.